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Two cases of acute postoperative Granulicatella adiacens endophthalmitis following uneventful phacoemulsification surgery are reported. The cases had intracameral cefuroxime as antibiotic prophylaxis, visual acuity (VA) was perception of light and hand movements, respectively, and there was severe anterior chamber inflammation and dense vitritis with no fundal view. Vitreous biopsy identified G. adiacens using genome sequencing. Intraoperative findings included extensive retinal hemorrhages, abscesses, occluded retinal vessels, and retinal necrosis. Due to the ischemic retinal appearance, pan-retinal photocoagulation endolaser was performed. Postoperatively both cases developed rhegmatogenous retinal detachment (RRD) anterior to the laser marks and were successfully treated. VA improved to 6/18 and 6/60, respectively. Hyperreflective dots and Henle fibre layer hemorrhage are reported for the first time, to the authors' knowledge, in association with endophthalmitis. The successful outcome suggested that intraoperative pan-retinal photocoagulation could be considered in such ischaemic cases to prevent rubeosis and to reduce the risk of postoperative RRD or limit its extent if it recurs.Photorefractive keratectomy (PRK) was performed to treat corneal epithelial basement membrane dystrophy (EBMD) found after femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) in a 29-year-old man with previous silent cornea. The patient was diagnosed with post FS-LASIK EBMD by siltlamp examination and in vivo confocal microscopy (IVCM). Initial treatment with topical lubricants and alcohol soaking were unsuccessful, and the patient continued to have blurred vision and discomfort. The patient had a PRK procedure and the symptoms resolved dramatically; residual refractive errors were also corrected. IVCM revealed a characteristic presentation of EBMD before PRK and normal corneal epithelium after treatment. Patients with asymptomatic EBMD might suffer from recurrent corneal erosions after FS-LASIK. Surface ablation including PRK might lead to successful treatment outcomes, and IVCM might provide helpful information before and after treatment.

To evaluate the accuracy of the measurements provided by a Scheimpflug camera combined with partial coherence interferometry for intraocular lens (IOL) power calculation.

I.R.C.C.S - G.B. Bietti Foundation, Rome, Italy.

Prospective case series.

Consecutive patients scheduled for cataract surgery were enrolled. Preoperative biometry was carried out with a Pentacam AXL (Oculus). Selleck Ruboxistaurin All patients received the same IOL (AcrySof SN60WF; Alcon). Measurements were entered into the following formulas Barrett Universal II, Emmetropia Verifying Optical (EVO) 2.0, Haigis, Hoffer Q, Holladay 1, Holladay 2 with axial length adjustment, Kane, Ladas Super Formula (LSF) 2.0, Næser 2, Pearl-DGS, SRK/T, T2, and VRF. When refraction was measured at 1 month postoperatively, the mean prediction error (PE), the median absolute error (MedAE), and the percentage of eyes with a PE within ±0.25, ±0.50, and ±1.00 diopter (D) were calculated after constant optimization.

Ninety-one eyes of 91 patients were analyzed. Comparison of the mean PE and MedAE did not reveal any statistically significant difference. However, the Pearl DGS formula achieved the lowest MedAE (0.19 D) followed by the LSF 2.0 (0.22). Twelve of the 13 formulas obtained a PE within ±0.50 D in at least 80% of eyes (range 80% - 87%) and 7 of them in at least 85%. Twelve formulas yielded a PE within ±0.25 D in at least 50% of eyes (range 51% - 64%).

All the investigated formulas performed well using the Pentacam AXL measurements. The newest Pearl DGS formula version and LSF 2.0 showed promising results.

All the investigated formulas performed well using the Pentacam AXL measurements. The newest Pearl DGS formula version and LSF 2.0 showed promising results.

To assess endothelial cell loss (ECL) rate and collect safety data in patients with AcrySof L-series Cachet phakic intraocular lens (pIOL) up to 10 years post-implantation.

Clinical settings in the United States, European Union, and Canada.

Nonrandomized, observational, open-label safety study.

Central and peripheral endothelial cell density (ECD) was evaluated and compared with 6-month post-implantation baseline. Nonlinear analysis was performed to identify factors affecting post-explantation ECL. Additional evaluations included uncorrected visual acuity (UCVA), corrected distance visual acuity (CDVA), adverse device effects (ADEs), and serious adverse events (SAEs).

The study included 1123 implanted eyes (mean age, 37.5 years). At 10 years, mean central and peripheral ECL was 16% (1.7% annualized). Explantations were performed in 10% of eyes (n=136/1323). For eyes with pIOL explantation because of ECL (7%), annualized ECL rate post-explantation was numerically lower compared with the overall rate eyes. Continued monitoring of patients regardless of explantation is recommended.Three patients developed recurrent corneal erosions (RCEs) over their cataract surgery corneal incisions. These cataract incision-related corneal erosions (CIRCEs) resulted in pain after cataract surgery. None had any physical findings for corneal erosion; thus, a new technique called the corneal sweep test was developed to identify the erosion. To the authors' knowledge, this is the first time this association between the clear corneal cataract incision and RCEs has been reported. Considering the high number of cataract surgeries performed around the world, it is important for ophthalmologists to recognize CIRCEs as a potential cause of ocular discomfort after clear corneal cataract surgery.

To evaluate the ease of replacement and capsular stability of a new fluid-filled, modular, accommodating intraocular lens (IOL) system composed of a monofocal base lens with a fluid lens clipped inside of it.

John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.

Experimental study.

Five New Zealand rabbits underwent bilateral phacoemulsification with implantation of the test lens (Juvene, LensGen) in both eyes (4 rabbits), or a control IOL in 1 eye (AcrySof, Alcon) and the test IOL in the other (1 rabbit). At 2 weeks, the 4 rabbits with bilateral Juvene IOLs had the clipped-in fluid lens exchanged for a new fluid lens in 1 eye, and the base and fluid lenses exchanged for a control lens in the contralateral eye. Slitlamp exams were performed weekly for 4 weeks. The globes were enucleated and evaluated with ultrasound biomicroscopy (UBM), grossly from the posterior Miyake-Apple view, and histopathologically.

Explantation/exchange of the fluid lens was considered straightforward by the surgeon.