Nortonhowell4915

The actin cytoskeleton-targeting/disrupting supramolecular assembly implies an excellent strategy for realizing efficient cancer therapy.Designing solid-state perovskite oxide solar cells with large short circuit current (JSC) and open circuit voltage (VOC) has been a challenging problem. Epitaxial BiFeO3 (BFO) films are known to exhibit large VOC (>50 V). However, they exhibit low JSC (≪μA/cm2) under 1 Sun illumination. In this work, taking polycrystalline BiFeO3 thin films, we demonstrate that oxygen vacancies (VO) present within the lattice and at grain boundary (GB) can explicitly be controlled to achieve high JSC and VOC simultaneously. While aliovalent substitution (Ca2+ at Bi3+ site) is used to control the lattice VO, Ca and Ti cosubstitution is used to bring out only GB-VO. Fluorine-doped tin oxide (FTO)/Bi1-xCaxFe1-yTiyO3-δ/Au devices are tested for photovoltaic characteristics. Introducing VO increases the photocurrent by four orders (JSC ∼ 3 mA/cm2). On the contrary, VOC is found to be less then 0.5 V, as against 0.5-3 V observed for the pristine BiFeO3. Ca and Ti cosubstitution facilitate the formation of smaller crystallites, which in turn increase the GB area and thereby the GB-VO. This creates defect bands occupying the bulk band gap, as inferred from the diffused reflection spectra and band structure calculations, leading to a three-order increase in JSC. The cosubstitution, following a charge compensation mechanism, decreases the lattice VO concentration significantly to retain the ferroelectric nature with enhanced polarization. BX-795 It helps to achieve VOC (3-8 V) much larger than that of BiFeO3 (0.5-3 V). It is noteworthy that as Ca substitution maintains moderate crystallite size, the lattice VO concentration dominates GB-VO concentration. Notwithstanding, both lattice and GB-VO contribute to the increase in JSC; the former weakens ferroelectricity, and as a consequence, undesirably, VOC is lowered well below 0.5 V. Using optimum JSC and VOC, we demonstrate that the efficiency ∼0.22% can be achieved in solid-state BFO solar cells under AM 1.5 one Sun illumination.Pesticides, extensively used in agriculture production, have received enormous attention because of their potential threats to the environment and human health. Hence, in this study, a kind of highly sensitive and stable hybrid surface-enhanced Raman scattering (SERS)-active substrates constructed with flower-like two-dimensional molybdenum sulfide and Ag (MoS2@Ag) has been developed, and then the above substrate was sequentially utilized in the recyclable detection of pesticide residues on several kinds of fruits and vegetables. In the first place, the excellent photocatalytic performance of the MoS2@Ag hybrid substrate was demonstrated, which was attributed to the inhibition of electron-hole combination after the formation of Schottky barrier between the Ag NPs and MoS2 matrix. Thereafter, two calibration curves with ultra-low limits of detection (LOD) as 6.4 × 10-7 and 9.8 × 10-7 mg/mL were established for the standard solutions of thiram (tetramethylthiuram disulfide, TMTD) and methyl parathion (MP), and then the recyclable assay of their single and mixed residues on eggplant, Chinese cabbage, grape, and strawberry was successfully realized. It is interesting to note that the detection recoveries from 95.5 to 63.1% for TMTD and 92.3 to 62.6% for MP are greatly dependent on the size and surface roughness of these foods. In a word, the MoS2@Ag composite matrix shows attractive SERS and photocatalysis performance, and it is expected to have the potential application on food safety monitoring.Thermochromic films with intriguing functionalities have great potential in soft actuators, heat storage devices, and interactive interface sensors. Inspired by the unique features of bird feathers (such as Nicobar pigeon, Anna hummingbird, mandarin duck, etc.), a superhydrophobic thermochromic film (STF) with robust healability is proposed for the first time through sandwiching an electric heater between a top thermochromic layer and a bottom poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) substrate. The STF exhibits fast and reversible color conversions of blue-pink-yellow under a low input power and has a superhydrophobic property with a contact angle of 155°. Furthermore, owing to the strong dynamic dipole-dipole interactions between the polar CF3 groups of flexible PVDF-HFP chains, the STF possesses a robust healing capability of structure and conductivity. By means of the temperature difference generated by the objects contacting (finger, iron, and water) as a stimulus, the STFs achieve tactile imaging and writing record with advantages of transient display, automatic erasure, and excellent reusability. Additionally, the STF-based anti-counterfeiting security labels with superhydrophobicity and three-state color switching simultaneously realize facile distinguishment and difficult forgery. The findings conceivably stand out as a new methodology to fabricate functional thermochromic materials for innovative applications.The factors governing bacterial adhesion to substrates with different topographies are still not fully identified. The present work seeks to elucidate for the first time and with quantitative data the roles of bacterial elasticity and shape and substrate topography in bacterial adhesion. With this aim, populations of three bacterial species, P. aeruginosa DSM 22644, B. subtilis DSM 10, and S. aureus DSM 20231 adhered on flat substrates covered with electrospun polycaprolactone fibers of different diameters ranging from 0.4 to 5.5 μm are counted. Populations of bacterial cells are classified according to the preferred binding sites of the bacteria to the substrate. The colloidal probe technique was used to assess the stiffness of the bacteria and bacteria-polymer surface adhesion energy. A theoretical model is developed to interpret the observed populations in terms of a balance between stiffness and adhesion energy of the bacteria. The model, which also incorporates the radius of the fiber and the size and shape of the bacteria, predicts increased adhesion for a low level of stiffness and for a larger number of available bacteria-fiber contact points. Te adhesive propensity of bacteria depends in a nontrivial way on the radius of the fibers due to the random arrangement of fibers.