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Conclusion A 475 mL test sample was used to examine the robustness of the RCP technique. The sample was 25% fat and had a fat mass of ( 116.67 ± 0.96 ) g. The measured fat mass from the RCP technique was 114.30 ± 0.98 g, or a 2% difference. The resonant cavity perturbation technique provides an accurate and repeatable measurement of fat mass in spherical phantoms and suggests the technology might be an effective obesity research tool for infants. Future studies will focus on extending the work to more complex anthropomorphic shapes.Purpose The literature is scarce on studies comparing secondary alveolar bone graft (SABG) performed early at approximately 5-6 years and at the conventional time at 9-11 years. This systematic literature review (SLR) aimed at comparing clinical outcomes after two different timings of SABG in children with unilateral and bilateral cleft lip and palate. Methods The inclusion criteria were autogeneous illiac grafts and the following study designs case control, cohort, clinical controlled trial (CCT), randomized CCT (RCCT), and previous SLRs. Ovid Medline, Ovid Embase, Web of Science, Scopus, Cochrane, ProQuest, and Google Scholar were the primary databases. Two calibrated examiners worked independently to select the articles. The MINORS evaluation method for surgical non-RCTs was used to assess for quality. Results 1,111 articles were retrieved and 19 qualified. Different clinical and radiographic outcomes such as bone level, periodontal status, canine eruption, and cleft-side tooth survival were evaluated by different assessment methods such as CBCT volume, computed tomography, periodontal evaluation, panoramic, intraoral radiographs, and Bergland scale. No RCCT or meta-analysis were found. None of the studies received the ideal score, which is 16 for non-comparison studies and 24 for comparison studies. Conclusion Methodological variation, lack of standardization for initial cleft dimension and low quality level rendered a fair comparison unfeasible. Selleckchem JQ1 Although further studies are necessary, it can be assumed that early SABG also can be an acceptable option, but this was based on a single study with a reasonable level of evidence.Background Despite the production of clinical practice guidelines (CPGs) in many medical areas, their use is not sufficiently adopted in clinical practice. Incorporation of CPGs in knowledge tools (KnowT) or decision support systems (DSS) for routine use can improve health care providers' compliance to CPGs. Materials and methods CPGs for gestational diabetes mellitus (GDM) were searched for collected and compared. The CPG that met pre-specified criteria [i) published by a European or American organization between 2010 and 2018, ii) being developed a systematic way and iii) having statements of "level of evidence" and "strength of recommendation"] was chosen for implementation (Endocrine Society, 2013). Its recommendations were deconstructed, re-organized and reconstructed as an algorithm (in the form of a flowchart), which was integrated into a KnowT. Content completeness and evaluation of CPG by the Guideline Implementability Appraisal tool (GLIA) tool were performed as well. The primary objective was the development of a clinical algorithm in the field of GDM and its integration into a KnowT. The secondary objective was to demonstrate the completeness of the CPG content and evaluate its implementability the KnowT. Results Endocrine Society 2013 CPG was restructured as a flowchart and a KnowT was constructed with the use of the "Openlabyrinth" software. The completeness of the content was confirmed, and GLIA appraisal demonstrated its implementability. Conclusion Endocrine Society 2013 CPG for GDM is a complete set of recommendations. Its structure makes possible the design of a clinical algorithm and its implementation into a KnowT.Fossil grass silica short cell phytoliths (GSSCP) have been used to reconstruct the biogeography of Poaceae, untangle crop domestication history, and detect past vegetation shifts. These inferences depend on accurately identifying the clade to which the fossils belong. Patterns of GSSCP shape and size variation across the family have not been established and current classification methods are subjective or based on a two-dimensional view that ignores important 3D shape variation. Focusing on Poaceae subfamilies Anomochlooideae, Pharoideae, Pueliodieae, Bambusoideae, and Oryzoideae we observed in-situ GSSCP to establish their orientation and imaged isolated GSSCP using confocal microscopy to produce three-dimensional models. 3D geometric morphometrics was used to analyze GSSCP shape and size. Classification models were applied to GSSCP from Eocene sediments from Nebraska, USA and Anatolia, Turkey. There were significant shape differences between nearly all recognized GSSCP morphotypes and between clades with shared morphotypes. Most of the Eocene GSSCP were classified as woody bamboos with some distinctive Nebraska GSSCP classified as herbaceous bamboos. 3D morphometrics hold great promise for GSSCP classification. It accounts for the complete GSSCP shape, automates size measurements, and accommodates the complete range of morphotypes within a single analytical framework.Objective In 2011, the government of Cameroon launched its performance-based financing (PBF) scheme. Our study examined the effects of the PBF intervention on the availability of essential medicines (EM). Methods Randomized control trial whereby PBF and three distinct comparison groups were randomized in a total of 205 health facilities across three regions. Baseline data were collected between March and May 2012 and endline data 36 months later. We defined availability of multiple EM groups by assessing stock-outs for at least one day over the 30 days prior to the survey date and estimated changes attributable to PBF using a series of difference-in-difference regression models, adjusted for relevant facility-level co-variates. Data were analysed stratified by region and area to assess effect heterogeneity. Results Our estimates suggest that PBF intervention had no effect on the stock-outs of antenatal care drugs (p=0.160), vaccines (p=0.396), integrated management of childhood illness drugs (p=0.681) and labour and delivery drugs (p=0.

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