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004). LPI significantly widened the ACA (range, 26.7-29.4%; P<0.05). ACA 500 increased by 29.4% (P<0.001), ACA 750 by 29.2% (P=0.002), SSA 500 by 27.3% (P=0.003), SSA 750 by 28.1% (P=0.001), AOD 500 by 28.6% (P=0.009), AOD 750 by 28.6% (P=0.003), TISA 500 by 27.3% (P=0.004), and TISA 750 by 26.7% (P=0.200).

SS-OCT ANTERION imaging can be used to reliably measure ACA before and after LPI. ACA, AOD, SSA, and TISA are all valid ACA measurement methods.

SS-OCT ANTERION imaging can be used to reliably measure ACA before and after LPI. ACA, AOD, SSA, and TISA are all valid ACA measurement methods.PRéCIS Regardless of the blood-filling patterns in Schlemm canal (SC) before the trabecular meshwork (TM) ablation, the trabectome surgery, combined with phacoemulsification, is effective for mild to moderate primary open-angle glaucoma patients.

The purpose of this study was to evaluate the association between trabectome surgery outcomes and the blood filling patterns in SC before TM ablation.

This retrospective cohort study included 105 eyes of 84 Japanese primary open-angle glaucoma patients who had undergone trabectome surgery in combination with cataract surgery. Provocative gonioscopy was performed before TM ablation to classify the blood filling patterns in SC into 3 groups no filling (group 1); patchy/irregular filling (group 2); and complete filling (group 3). The subjects were divided into 3 groups according to the blood filling patterns and the trabectome surgery outcomes were compared, including intraocular pressure (IOP), the percentage reduction in IOP, surgical success rate, and the number of glaucoma medications. Success was defined by IOP ≤15 mm Hg and a >20% reduction in IOP with/without glaucoma medication, and without additional glaucoma surgery after trabectome surgery combined with cataract surgery.

Twenty-four eyes were assigned to group 1, 48 to group 2, and 33 to group 3. Between-group analyses showed no significant intergroup differences in age (P=0.213), preoperative mean deviation (P=0.505), preoperative and postoperative IOP (P=0.941 and 0.458, respectively), preoperative and postoperative number of glaucoma medications (P=0.805 and 0.077, respectively), percentage IOP reduction (P=0.256), and success rates (P=0.540).

Trabectome surgery is effective for mild to moderate primary open-angle glaucoma patients, independent of the blood-filling patterns in SC before the TM ablation.

Trabectome surgery is effective for mild to moderate primary open-angle glaucoma patients, independent of the blood-filling patterns in SC before the TM ablation.PRéCIS Small but significant decreases in optical coherence tomography angiography (OCTA)-measured circumpapillary capillary density (cpCD) were observed in healthy eyes dilated with 2.5% phenylephrine/0.5% tropicamide. Although likely clinically insignificant, ophthalmologists should consider these changes when interpreting OCTA results from dilated eyes.

The purpose of this study was to investigate the effect of pupil dilation using 2.5% phenylephrine and 0.5% tropicamide on quantitative assessment of retinal microvasculature using OCTA.

OptoVue AngioVue high density (HD) and non-HD OCTA macula and optic nerve head (ONH) images were obtained at 15-minute intervals predilation and postdilation in 26 healthy participants (mean age 40.0; 95% confidence interval=33.9, 46.1 y). Superficial macular vessel density (VD) was measured in the whole image VD and the parafoveal region VD. ONH capillary density was measured in the whole image capillary density and the cpCD region. Differences between predilation and pties, as well as older individuals.

Pupil dilation using topical 2.5% phenylephrine and 0.5% tropicamide results in a small but statistically significant reduction in non-HD ONH whole image and cpCD in healthy eyes. The observed reduction likely is not clinically significant because the observed reduction was within the previously reported range of measurement variability. Further studies should consider investigating these effects in nonhealthy eyes with glaucoma and media opacities, as well as older individuals.PRéCIS The XEN45 Gel Stent can be implanted after failed trabeculectomy without disadvantages compared with primary implantation.

We aimed to compare the outcomes of XEN45 Gel Stent (Allergan, CA, USA) implantation in pseudophakic eyes after failed trabeculectomy and in pseudophakic eyes without other previous surgeries.

In this retrospective study, we included 30 pseudophakic eyes of 30 patients who underwent XEN45 Gel Stent implantation after failed trabeculectomy (trabeculectomy group) and 60 eyes of 60 patients with primary XEN45 Gel Stent implantation (control group). The groups were matched for preoperative intraocular pressure (IOP), preoperative medication score, cup-to-disc ratio, follow-up time, visual acuity and age at a ratio of 12. Eyes with concomitant eye diseases, those who had undergone previous surgery, and those with a follow-up duration <6 months were excluded. We compared the success rates based on different criteria Criteria A (IOP <21▒mmHg, IOP reduction >20%, no repeat surgery); Criteria B (IOP <18▒mmHg, IOP reduction >20%, no repeat surgery); and Criteria C (IOP ≤15▒mmHg, IOP reduction ≥40%, no repeat surgery).

After an average follow-up period of 20 months, the mean IOP was reduced from 24.4±5.7 to 14.0±4.1▒mmHg in all the study subjects (90 patients). There were no significant differences between the two groups in postoperative IOP, postoperative medication score, revision rate, and repeat surgery rate or success rate.

XEN45 Gel Stent implantation is a viable option after failed trabeculectomy. According to our results, it has no disadvantage compared with primary XEN45 Gel Stent implantation.

XEN45 Gel Stent implantation is a viable option after failed trabeculectomy. According to our results, it has no disadvantage compared with primary XEN45 Gel Stent implantation.PRéCIS Swedish Interactive Threshold Algorithm (SITA) Faster (SFR) saves considerable test time but needs further amendments for considering it to be an accurate test that can replace SITA Fast (SF) or SITA Standard (SS).

To compare visual field results obtained using SFR, SF, and SS programs in patients with manifest and suspect glaucoma.

In this cross-sectional observational study involving manifest patients with glaucoma and glaucoma suspects, perimetric outcomes of SFR, SF, and SS were compared. Outcomes included test time, mean deviation, pattern standard deviation (PSD), Visual Field Index (VFI), foveal threshold, number of points depressed at P<5%, P<2%, P<1%, and P<0.5% on PSD probability plot, individual threshold test points, glaucoma hemifield test, and grade of field defect.

Seventy eyes of 70 patients were included in this study. SFR test times averaged 36.1% shorter than SF and 60.7% shorter than SS (P<0.001). Dabrafenib solubility dmso Mean deviation values were lower with SFR compared with both SF and SS (Δ=1.