Gordonbossen5943

4-102.3% in tap water samples and showed good application prospects for the analysis and detection of BPA.The design and construction of a photoelectrochemical (PEC) sensor with excellent photoelectric properties and good photoelectrocatalysis activity is significant for the effective detection of analytes. In this paper, based on a two-step anodic oxidation method and successive ionic layer adsorption (SILAR) method, a TiO2 nanotube array (TNT) photoelectrochemical sensor modified with BiOBr nanosheets was constructed and applied for the detection of H2O2 for the first time. The photocurrent of the photoelectrochemical sensor increases with the increase of the H2O2 concentration under the irradiation of an 8 W UV lamp. Excellent linearity was obtained in the concentration range from 10 nM to 100 μM with a low detection limit of 5 nM (S/N = 3). This excellent photoelectrochemical performance is due to the formation of a p-n heterojunction between BiOBr and TiO2 nanotube arrays, which provides efficient separation of charge carriers and accelerates electron transport. Moreover, it is applied to detect H2O2 in milk samples and it showed a good recovery result ranging from 95.73% to 105.65%, which provides a promising new strategy for the detection of H2O2.Drug discovery is a complex process in which many challenges need to be overcome, from the discovery of a drug candidate to ensuring the efficacy and safety of the candidate in humans. Modern analytical methods allow tens of thousands of drug candidates to be screened for their inhibition of specific enzymes or receptors. In recent years, fluorescent probes have been used for the detection and diagnosis of human pathogens as well as high-throughput screening. This review focuses on recent progress in organic small-molecule based enzyme-activated fluorescent probes for screening of inhibitors from natural products. The contents include the construction of fluorescent probes, working mechanism and the process of inhibitor screening. The progress suggests that fluorescent probes are a vital and rapidly growing technology for inhibitor screening of enzymes, in particular, inhibitor screening in situ.Herein, we illustrate the preparation of a covalent connected peptide-porphyrin hybrid (Fmoc-FF-(Zn)Por). The thorough investigation of its self-organization features demonstrated that Fmoc-FF-(Zn)Por self-assembles into either spheres or fibrils by altering the solvent mixture. Interestingly, photocatalytic hydrogen (H2) evolution experiments revealed that fibrils were more efficient towards H2 production compared to spheres.Carbon dots (CDs) that exhibit fluorescence properties are generally derived from carbonaceous materials, and possess ultrasmall sizes with various exciting physical, chemical and photo-properties, which have been used in many different fields in recent time. Here, we have focused on the preparation of nitrogen-doped CDs (N-CDs) that emit a bright blue fluorescence upon exposure to UV excitation. Furthermore, by employing Rhodamine B (RhB) as a donor molecule, the emission color of N-CDs is altered from blue to red. Interestingly, the optical tuning based upon emission from one particular color to various other colors has been achieved by varying the doping ratio of the donor molecule, RhB. The reason is mainly attributed to the non-radiative energy transfer of the exciton energy from an excited donor to an acceptor through fluorescence resonance energy transfer (FRET). Furthermore, this emission behavior is explored for the ratiometric sensing of mercury ion (Hg2+) in aqueous medium. Among different color emissions, we chose one particular emission color, namely violet, for the detection of the Hg2+ ion. The photoluminescence properties of N-CDs are effectively and systematically quenched with the addition of different mercury ion concentrations, leading to efficient energy transformation arising from the synergetic effect of the electrostatic interaction and metal - ligand coordination between the surface functional groups of N-CDs and Hg2+ ion. On the other hand, RhB has no interaction with Hg2+ ions. These findings provide a way for developing a cheap, selective and suitable sensing matrix for the detection of toxic metal ions, such as mercury (Hg2+) at a low concentration level.Herein, a graphene field effect transistor (GFET) was constructed on an optic fiber end face to develop an integrated optical/electrical double read-out biosensor, which was used to detect target single-stranded DNA (tDNA). Two isolated Au electrodes were, respectively, prepared as the drain and source at the ends of an optic fiber and coated with a graphene film to construct a field effect transistor (FET). Probe aptamers modified with fluorophore 6'-carboxy-fluorescein (6'-FAM) were immobilized on the graphene for specific capture of tDNA. Graphene oxide (GO) was introduced to quench 6'-FAM and construct a fluorescence biosensor. Thus, a dual GFET and fluorescence biosensor was integrated on the end-face of an optic fiber. Following synchronous detection by fluorescence and FET methods, results showed satisfactory sensitivity for DNA detection. Compared with conventional biosensors using a single sensing technology, these dual sensing integrated biosensors significantly improved the reliability and accuracy of DNA detection. Furthermore, this proposed technique provides both a new biosensor for single-stranded DNA detection and a strategy for designing multi-sensing integrated biosensors.A novel conversion reaction synthesis (CRS) method is used to synthesize ZnO-supported Co nanoporous metal hybrid structures from a co-precipitated nanocomposite precursor of ZnO and Co3O4. After removal of Li2O with water, the resulting material consists of ZnO-supported Co nanoparticles that are interconnected to form anisotropic micro-particles. Additionally, individual ZnO nanoparticles have an anisotropic morphology, as revealed by synchrotron XRD analysis. Microscopy and surface area studies show these materials have an average pore size of 10-30 nm and specific surface areas up to 28 m2 g-1. The hybrid structure also has increased heat resistance compared to that of pure nanoporous metals; the Co phase within the ZnO-Co hybrid exhibits much less coarsening than the analogous nanoporous metal without ZnO at temperatures of 400 °C and above. LDC7559 These ZnO-Co hybrid materials were tested as heterogeneous catalysts for the steam reformation of ethanol at 400 °C. The nanoporous ZnO-Co hybrid material exhibits complete conversion of ethanol and high hydrogen selectivity, producing H2 with a molar yield of approximately 70%.