Valentinetherkelsen7213

Sclerosing angiomatoid nodular transformation of spleen is a rare, benign vascular lesion with an uncertain pathogenesis. It has been described as a separate entity through specific histopathological characters. It is usually asymptomatic, occurring commonly in adult females. Only a few cases of paediatric cases have been reported which have been commonly symptomatic. This disease has excellent prognosis after splenectomy, which is the only treatment. We report the case of an eight-year-old girl who presented with distended abdomen and history of bleeding from the nose following a road traffic accident. Examination revealed stunted height, decreased weight, tachypnoea, tachycardia, anaemia and a firm, massive spleen. Lab investigations further revealed microcytic anaemia, thrombocytopenia, deranged platelet profile and low vitamin B12 and folate levels. Computed tomography confirmed enlarged spleen. KWA 0711 in vivo Therefore, a diagnostic biopsy was planned which confirmed sclerosing angiomatoid nodular transformation of spleen. Splenectomy was successfully performed soon after and the child is now healthy with no remissions of previous symptoms.Adenoid cystic carcinoma of the Bartholin gland is a rare vulval cancer. Available literature suggests an aggressive nature with protracted clinical symptoms and local recurrence despite adequate surgical excision with or without adjuvant radiotherapy. This case demonstrates the role of neoadjuvant chemotherapy and interstitial brachytherapy with less radical surgery, in the treatment of adenoid cystic carcinoma of the Bartholin gland. A 63-year-old woman presented in the clinic four months after the removal of vulvar mass with histopathology report showing adenoid cystic carcinoma of the Bartholin gland with positive margins. Clinical examination and imaging showed local disease extension up to the levator ani and abutting anal margin. She was given four cycles of neoadjuvant chemotherapy followed by ipsilateral hemivulvectomy with inguino-femoral lymphadenectomy followed by 25 cycles of external beam radiation and three cycles of interstitial brachytherapy. The patient has been disease free for more than 30 months. The use of neoadjuvant chemotherapy in treatment of Bartholin carcinoma along with conser vative surgery and radiotherapy can be a good treatment strategy as it reduces the morbidity associated with radical surgery without recurrence to date.Cerebral Palsy (CP), a non-progressive motor disorder, which arises due to lesions of the brain during pregnancy, labour or shortly after birth effects 1-1.5/1000 live births. Altogether 658 CP cases were acquitted from 14 health organizations that permitted access to the data. Data was assembled with respect to topography, muscle tone, severity level and Gross Motor Function Classification System (GMFCS) is accompanied by the comorbidities and co-mitigating factors from 2010-2016. Data represented topographically showed a greater percentage of quadriplegic cases i.e.186 (39.9%). Spastic tone was the most commonly presented muscle tone i.e. 352 (53.4%) and 235 (57.7%) cases were in the mild severity zone. Level II was the most prevalent GMFCS i.e. 189 (34.4%). The most prevalent comorbidity was epilepsy i.e. 96 (14.58%) and co-mitigating factor was Attention Deficit/Hyperactivity Disorder i.e. 18 (2.73%). A dominant male to female ratio was seen as 1.41. The prevalence of males was exhibiting an increase of 80.3% in contrast to females.The objective of this study was to determine the prevalence of preventable risk factors of acute kidney injury in a tertiary care hospital in Pakistan. All patients admitted at Aga Khan University Hospital, Karachi with diagnosis of acute kidney injury were included out of which 134 were selected via random sampling. Patients with existing CKD were excluded. Data was then collected retrospectively from medical records of these patients. Mean age was 60±11.7 years while mean serum creatinine on admission was 2.4±1.3 (mg/dl). Sepsis played a role in almost half of the patients [60 (45%)]. Other factors included diarrhoea [23 (17%)], nephrotoxic drug use [25 (19%)] and cardiac pathology [24 (18%)]. It was found that most cases of AKI were due to preventable factors (infections, diarrhoea, and drug toxicity) and concerted efforts to eliminate them would be vital in reducing mortality caused by AKI in developing countries.Team objectively structured bed side assessment (TOSBA) is one of the tools used by medical students to assess teamwork. The aim of this study was to measure the team scores and to correlate team performance scores with individual performance in final year medical students using TOSBA. It was a quasi-experimental study including 100 students, divided into 22 teams comprising of 4-6 members. TOSBA sessions were setup for module assessment of teams. Their individual and team performance scores were measured. Correlation between individual and team scores was calculated using Pearson correlatio n test. Results of the study showed seven (7) high scoring, eight (8) medium scoring and seven (7) low scoring teams. Team scores had a statistically significant correlation with individual scores (p less then 0.05). Reliability of the tool was 0.58 with a high convergent validity. TOSBA is a tool that can be used for individual and team assessment during clerkships.A study was conducted to determine the frequency of allergic rhinitis among healthcare professionals and its impact on their work at the Aga Khan University Hospital Karachi Pakistan. Healthcare workers including doctors, nurses, technicians and pharmacists were included. Participants were asked to fill a questionnaire consisting of score for allergic rhinitis (SFAR), and work productivity and activity impairment questionnaires. Out of 167 workers, 101 were males. Mean age of the participants was 29.0 ± 5.9 years. Overall prevalence of allergic rhinitis among healthcare workers was found to be frequency (19.2%). We noted that 13 individuals reported to have missed their work in the past week accounting to 4.3% of their work. When calculated with the actual work hours 35.9% of their work was reported to have been impaired due to this condition.