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DNA repair can prevent mutations and cancer development, but it can also restore damaged tumor cells after chemo and radiation therapy. We performed RNA sequencing on 95 human pathological thyroid biosamples including 17 follicular adenomas, 23 follicular cancers, 3 medullar cancers, 51 papillary cancers and 1 poorly differentiated cancer. The gene expression profiles are annotated here with the clinical and histological diagnoses and, for papillary cancers, with BRAF gene V600E mutation status. DNA repair molecular pathway analysis showed strongly upregulated pathway activation levels for most of the differential pathways in the papillary cancer and moderately upregulated pattern in the follicular cancer, when compared to the follicular adenomas. This was observed for the BRCA1, ATM, p53, excision repair, and mismatch repair pathways. This finding was validated using independent thyroid tumor expression dataset PRJEB11591. We also analyzed gene expression patterns linked with the radioiodine resistant thyroid tumors (n = 13) and identified 871 differential genes that according to Gene Ontology analysis formed two functional groups (i) response to topologically incorrect protein and (ii) aldo-keto reductase (NADP) activity. We also found RNA sequencing reads for two hybrid transcripts one in-frame fusion for well-known NCOA4-RET translocation, and another frameshift fusion of ALK oncogene with a new partner ARHGAP12. The latter could probably support increased expression of truncated ALK downstream from 4th exon out of 28. Both fusions were found in papillary thyroid cancers of follicular histologic subtype with node metastases, one of them (NCOA4-RET) for the radioactive iodine resistant tumor. The differences in DNA repair activation patterns may help to improve therapy of different thyroid cancer types under investigation and the data communicated may serve for finding additional markers of radioiodine resistance.Micro Electro Mechanical System (MEMS) energy harvester's research interests have been increasing rapidly, indicating that the topic has given significant contributions to the sustainable development of energy alternatives. Although many research activities have been conducted and reported since several years ago, only limited efforts have been made to analyze the research's impact in this area. NVP-CGM097 ic50 In this paper, we report a bibliometric analysis on the research progress in MEMS for energy harvester. VOSviewer software is used to support the analyst that includes the distributions of the publication journals, authors, affiliations and the highly cited papers reporting the progress as well as the frequency of keywords and their relationships found in the search engine. The analysis is mainly aimed to identify the research map based on publication reports. 1772 papers were initially identified and summarized based on the analysis on three focused mainstream research topics in MEMS for alternative energy, such as MEMS energy harvester, power harvesting and energy scavenging, other term analogies to MEMS such as micromachines and microsystem were included in the analysis parameter. As a result, it is found that the study on the MEMS energy harvester is mostly categorized in the engineering field, while China has been conducting the most projects. The Journal MEMS and Journal of Micromechanics and Microengineering have been the most journals publishing reports on MEMS energy harvester's research progress. Based on these analyses, some potential issues in future MEMS energy harvester research have been identified, including the contributions of new materials, the MEMS new structure's involvement, and the optimization of the vibration concepts and principles of MEMS energy harvester. These analyses would give an overview on the progress of the development and improvement in MEMS energy harvester and give a proper guideline for future MEMS research in the energy field.This study was examined effects of automated teller machine (ATM) service quality on client satisfaction within the Commercial Bank of Ethiopia (CBE). During this study, the convenience sampling technique was employed. The study used primary and secondary data sources. Both quantitative and qualitative data types were collected. Data were analyzed by using five-point Likert scale and Econometric methods. Multinomial and ordered logit model was used to analyze the effect of service quality of ATM service on client satisfaction. The mean Likert scale result indicated that the respondents' attitude towards tangibles, reliability, responsiveness, assurance and empathy fall on 2.77, 2.98, 2.58, 3.02 & 3.23, respectively. The econometric result confirmed positive relationship between tangibles, reliability, responsiveness, empathy and assurance, and client satisfaction. Based on the finding of this study providing reliable network, educating customers on ATM usage, improving the security of ATM usage, increasing the number of ATMs, and increasing the amount of money withdrawn was recommended.The purpose of this study is to determine how the perceptions and understandings of hotel managers in East Java to improve the corporate image as a hotel marketing strategy. Research respondents are managers who work in the hospitality industry. A total of ninety-six stars hotel in East Java were assessed. Each star hotel has nine managers so that the study population is 621 managers. The research sample of 232 managers. The sampling technique is simple random sampling. Statistical techniques used Confirmatory Factor Analysis (CFA) and descriptive analysis of mean and mode. This research is related to the success of the hospitality marketing strategy; therefore, it is urgent to conduct an in-depth investigation of the corporate image of the hotel. The results showed that managers who work in the hotel industry better understand the corporate image of the hotel at an psychological level to maintain trust in customers. Trust becomes part of the psychological managers in implementing corporate image practices in the hospitality industry.Food insecurity caused by climate change has become one of the main issues on the global agenda. Worldwide, the importance of digital tools as a means to enhance adaptive capacity and resilience of smallholder farmers (SHFs) in the face of climate variability has long been recognised. Technology-based systems in agriculture frequently neglect to consider the actual context of use and adoption by SHFs in rural and developing contexts. These conditions, as pointed out in the literature, range from high "illiteracy" rates to poor technology infrastructure to a requirement for smartphone-based technology of which very few SHFs in the developing world can take advantage. However, very little is known about the information and communication technology (ICT) literacy levels of SHFs in general in terms of supporting them in their farming decisions. This paper, therefore, explores the ICT literacy levels of Msinga SHFs in order to understand what could enhance their use and adoption of ICT for weather forecasting. Msinga is a hotspot for climate change.