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Hepatitis C and B were the most frequent infections, followed by syphilis in the sample.

To give painless and stable fingertips to patients by means of vertical figure-of-eight tension sutures.

The longitudinal study was carried out from May to October 2019 at the Dow University of Health Science, Civil Hospital, Karachi, and comprised individuals of either gender aged 10-60 years. All patients were surgically managed and were assessed clinically and with radiological films for finger stability and fracture healing during 3-month follow-up. Data was collected using a proforma and was analysed using SPSS 21.

Of the 74 patients, 58(78.4%) were males and 16(21.6%) were females. The overall mean age was 28.9±13.23 years. Of the total, 65(88%) were operated under local anaesthesia, while 9(12%) were given general anaesthesia. All 74(100%) patients on early visits had pain and discomfort, 5(6.8%) had infection and none had ischaemic insult.

Using vertical figure-of-eight tension sutures was found to be a simple technique which helped in proper healing of distal phalanx fractures and a non-deformed fingertip.

Using vertical figure-of-eight tension sutures was found to be a simple technique which helped in proper healing of distal phalanx fractures and a non-deformed fingertip.

To calculate the incidence of post-transplant erythrocytosis, and to assess the response to treatment.

The prospective study was conducted from April 2016 to April 2018 at the Department of Nephrology, Bahria International Hospital, Lahore, Pakistan, and comprised patients undergoing renal transplantation who were evaluated and followed up for 12 months. Patients having haemoglobin levels ≥17gm/dl were labelled as having polycythemia. Data was analysed using SPSS 21.

Of the 94 total patients, 69(73.4%) were enrolled. During follow-up, 2(2.9%) of them died, and, thus, the final sample stood at 67(71.3%); 57 (85%) males and 10(15%) females. The mean age of the sample was 32.6±8.8 years. Overall, 19(28.4%) patients developed polycythemia and they were either given angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers. Of these 19 patients, 11(57.8 %) responded to the treatment, while 8(42.1%) required phlebotomy. Further, 3(15.7%) patients required one phlebotomy, while 5(26.3%) who had glomerular filtration rate >30% had to have repeated phlebotomy.

The incidence of post-transplant erythrocytosis was significantly high at 28.4%.

The incidence of post-transplant erythrocytosis was significantly high at 28.4%.

To determine outcome of first relapse of Hodgkin lymphoma with standard dose chemotherapy, and to identify the prognostic factors predicting survival outcome in paediatric patients.

The retrospective study was conducted at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, and comprised data of Hodgkin lymphoma patients who relapsed at least 3 months after the completion of initial treatment from January 2001 to December 2010. Probabilities of overall survival, event-free survival and cumulative incidence were calculated. Data was analysed using SPSS 21.

Of the 43 patients, 31(72%) were males and 12(29%) were females. Mean age at relapse was 11±3.3 years (range 4-17 years). In 31(72%) patients, early post-operative intraperitoneal chemotherapy was employed. Median follow-up of the cohort was 62 months (interquartile range 4-187 months). Overall survival and event-free survival at 10 years was 23(54%) and 15(35%) respectively. On univariate analysis, initial disease stage (p=0.021), stage at relapse (p=0.003), treatment protocol (p=0.005), treatment responsiveness at initial two cycles of salvage chemotherapy (p=0.002) and at the end of treatment assessment (p=0.0009) were statistically significant factors. Multivariate cox regression analysis revealed disease stage at relapse (p=0.004), chemotherapy regimen (p=0.025) and end-of-treatment disease evaluation (p=0.005) as the significant variables.

Improved outcome with early post-operative intraperitoneal chemotherapy regimen was noted for Hodgkin lymphoma patients who had disease-free interval >2 years.

2 years.

To compare two different skeletal anchorage methods with finite element analysis in the treatment of Class III patients with maxillary retrognathia.

Two different treatment scenarios were performed on skull model obtained from computerized tomography images of skeletal Class III patients with maxillary retrognathia and finite element analysis was performed. In the first group; mini plates were simulated on infra zygomatic crest. A unilateral 500 g protraction force was applied to the face-mask. In the second group; mini plates were simulated in infrazygomatic crest and mandibular symphysis. Then, 500g protraction force was applied with Class III elastic between the miniplates. Von Misses stresses and displacement values were evaluated comparatively.

In Class III elastic group, maximum Von Misses stress occurred around infra zygomatic crest and symphysis anchored with 0.078 MPa. The maxillary posterior region and paranasal regions were the areas showing the highest Von Misses tension after infra zygomatic crest and symphysis. In the face-mask group, the most common site of Von Misses stress in nasomaxillary complex and alveolar structures were infra zygomatic area where plaques were applied, followed by pterygomaxillary suture. Tensile forces are reduced especially in these two areas by spreading to surrounding structures.

In both methods, it was determined that the amount of force transmitted to circumaxillary sutures was sufficient to induce the formation of osteogenesis in these regions.

In both methods, it was determined that the amount of force transmitted to circumaxillary sutures was sufficient to induce the formation of osteogenesis in these regions.

To explore the factors affecting the learning process of novice problem-based learning facilitators trained through Cognitive Peer Coaching.

The qualitative study with phenomenological design was conducted at the Islamic International Medical College, Riphah International University, Islamabad, Pakistan, from March to August 2018, and comprised problem-based learning facilitators, experts and novices who were given orientation about cognitive peer coaching through workshops. selleck compound Novice facilitators were trained by experts through cognitive peer coaching cycle comprising pre-observation, observation and post-observation phases following socio-cognitive apprenticeship theory based on modelling, coaching, scaffolding, articulation, reflection and exploration. Data was collected through an observation checklist and semi-structured interviews which were audio-recorded, transcribed and subjected to thematic analysis manually.

Of the 15 subjects, 10(66.6%) were novice facilitators and 5(33.3%) were experts. Six themes generated and they were mental growth spurred from within, conscientisation, experiential learning, intrinsic motivation, effective body language, and impediment to success.

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