Wagnerholmes7279

We explain the current results based on expectancy violations theory. When competence scandals take place in competence stereotype countries, there will be a greater degree of violation of expectations compared with that in warmth stereotype countries, which leads to a negative evaluation of the country of origin. When morality scandals take place in warmth stereotype countries, people had a stronger negative emotional arousal when morality scandals happened in the warmth stereotype country. Copyright © 2020 Fan, Li and Jin.The lateral parabrachial nucleus, medial parabrachial nucleus, vestibular nuclei complex, and medullary viscero-sensory-motor (VSM) nuclei complex (the latter including among others the solitary nucleus, vagus nerve nucleus, and hypoglossal nucleus) are anatomically and functionally connected brainstem gray matter structures that convey signals across multiple modalities between the brain and the spinal cord to regulate vital bodily functions. It is remarkably difficult to precisely extrapolate the location of these nuclei from ex vivo atlases to conventional 3 Tesla in vivo images; thus, a probabilistic brainstem template in stereotaxic neuroimaging space in living humans is needed. We delineated these nuclei using single-subject high contrast 1.1 mm isotropic resolution 7 Tesla MRI images. After precise coregistration of nuclei labels to stereotaxic space, we generated a probabilistic template of their anatomical locations. Finally, we validated the nuclei labels in the template by assessing their inter-rater agreement, consistency across subjects and volumes. We also performed a preliminary comparison of their location and microstructural properties to histologic sections of a postmortem human brainstem specimen. In future, the resulting probabilistic template of these brainstem nuclei in stereotaxic space may assist researchers and clinicians in evaluating autonomic, vestibular and VSM nuclei structure, function and connectivity in living humans using conventional 3 Tesla MRI scanners. Copyright © 2020 Singh, Indovina, Augustinack, Nestor, García-Gomar, Staab and Bianciardi.The auditory front-end is an integral part of a spiking neural network (SNN) when performing auditory cognitive tasks. LDK378 ALK inhibitor It encodes the temporal dynamic stimulus, such as speech and audio, into an efficient, effective and reconstructable spike pattern to facilitate the subsequent processing. However, most of the auditory front-ends in current studies have not made use of recent findings in psychoacoustics and physiology concerning human listening. In this paper, we propose a neural encoding and decoding scheme that is optimized for audio processing. The neural encoding scheme, that we call Biologically plausible Auditory Encoding (BAE), emulates the functions of the perceptual components of the human auditory system, that include the cochlear filter bank, the inner hair cells, auditory masking effects from psychoacoustic models, and the spike neural encoding by the auditory nerve. We evaluate the perceptual quality of the BAE scheme using PESQ; the performance of the BAE based on sound classification and speech recognition experiments. Finally, we also built and published two spike-version of speech datasets the Spike-TIDIGITS and the Spike-TIMIT, for researchers to use and benchmarking of future SNN research. Copyright © 2020 Pan, Chua, Wu, Zhang, Li and Ambikairajah.Repetitive traumatic brain injury (rTBI) is a major health care concern that causes substantial neurological impairment. To better understand rTBI, we introduced a new model of rTBI in mice induced by sudden rotation in the coronal plane combined with lateral translation delivered twice at an interval of 24 h. By routine histology, histological examination of Prussian blue-stained sections revealed the presence of microbleed in the corpus callosum and brain stem. Amyloid precursor protein (β-APP) and neurofilament heavy-chain (NF-200) immunohistochemistry demonstrated axonal injury following rTBI. Swelling, waving, and enlargement axons were observed in the corpus callosum and brain stem 24 h after injury by Bielschowsky staining. Ultrastructural studies by electron microscopy provided further insights into the existence and progression of axonal injury. rTBI led to widespread astrogliosis and microgliosis in white matter, as well as significantly increased levels of tumor necrosis factor (TNF)-α and interleukin (IL)-1β. rTBI mice showed a significantly increased loss of righting reflex (LRR) duration within each time point compared with that of sham animals, which was under 15 min. rTBI mice exhibited depression-like behavior at 1 month. rTBI mice also demonstrated deficits in MWM testing. These results suggested that this model might be suitable for investigating rTBI pathophysiology and evaluating preclinical candidate therapeutics. Copyright © 2020 Chen, Gu, Zhu and Feng.Diffusible ions (Na+, K+, Mg2+, Ca2+, Cl-) are vital for healthy function of all cells, especially brain cells. Unfortunately, the diffusible nature of these ions renders them difficult to study with traditional microscopy in situ within ex vivo brain tissue sections. This mini-review examines the recent progress in the field, using direct elemental mapping techniques to study ion homeostasis during normal brain physiology and pathophysiology, through measurement of ion distribution and concentration in ex vivo brain tissue sections. The mini-review examines the advantages and limitations of specific techniques proton induced X-ray emission (PIXE), X-ray fluorescence microscopy (XFM), secondary ion mass spectrometry (SIMS), laser-ablation inductively coupled plasma mass spectrometry (LA-ICP-MS), and the sample preparation requirements to study diffusible ions with these methods. Copyright © 2020 Hartnell, Andrews, Smith, Jiang, McAllum, Rajan, Colbourne, Fitzgerald, Lam, Takechi, Pushie, Kelly and Hackett.Video-oculography during free visual exploration (FVE) is a valuable tool to evaluate visual attention spatial allocation in neglect patients after right-hemispheric stroke. In conventional FVE analyses, the position of a visual fixation is conceived as a single point in space. Here, we describe a new complementary method to analyze FVE data based on foveal vision, leading to an accurate estimate of the portion of the picture that was effectively explored. In 15 neglect patients and 20 healthy controls, visual exploration areas (i.e., considering 1° visual angle around every single fixation) were computed. Furthermore, the proportion of single and overlapping fixations was analyzed. Overlapping fixations were further categorized into capture fixations (successive overlapping fixation, putatively reflecting problem of disengagement) and re-capture fixations (temporally distant overlapping fixations, putatively reflecting spatial working memory deficits). The results of this new analysis approach were compared to the ones of conventional approaches.