Timmdobson8900

Purpose This descriptive study was conducted for the purpose of determining the effect of sociodemographic characteristics of university students on emotional eating behavior. Design and methods The study was completed with a total of 537 students. A descriptive questionnaire and the Emotional Eating Scale were used. Descriptive statistics, correlation, and regression analyses were used. Finding It was found that emotional eating was positively correlated with body mass index and weight. It was determined that variables such as will, anger, body mass index, and weight were predictors of emotional eating. Practical implications Emotional eating is a coping response with negative emotions. It is suggested that will is the most important factor affecting emotional eating. Thus, psychological dimension of wrong eating habit should definitely be addressed.Objective To investigate Schistosoma haematobium morbidity in infected pre-school age children and establish their disease burden. Methodology Pre-school age children (1-5years) who were lifelong residents of the study area and had no other infections were included in the study. Participants underwent a physical examination with clinicians blinded to their infection status. Diagnosis of S. haematobium was by urine filtration. Results The prevalence of S. haematobium was 35.1%(146/416). The clinical features observed in patients with Schistosoma. haematobium were wheezes (morbidity attributable factor (AF=93.9%), haematuria (AF=92.6%), ascites (AF=91.5%), atopy (AF=76.9%), inguinal lymphadenopathy(AF=68.4%), stunting (AF=38.2) , malnutrition (MUAC)(AF=20%) and weight for height scales (AF=5%). Schistosoma. haematobium infected children were at greater odds ratio of presenting with inguinal lymphadenopathy (AOR)=99.2(95% CI 24.2 to 854.5), wheezes in the chest (AOR=35.4 95% CI 15.3 to 94.2), Distended abdomen with ascites (AOR=23.9 95% CI 11.4 to 54), haematuria (AOR=12.6 95% CI 11.6 to 14.1), atopy history (AOR=5.6 95% CI 1.85 to 20.2), malnutrition (AOR=2.3 95% CI 1.4 to 3.2) and stunting (AOR= 1.9 95% CI 1.1 to2.7). Conclusion The study is novel as it demonstrates for the first time clinical morbidity markers associated with S. haematobium infection in pre-school age children. Furthermore the study adds scientific evidence to the call for inclusion of pre-school age children in schistosomiasis control programs. These morbidity markers highlight the need for early diagnosis and screening for S. haematobium in preschool age children.The present study aimed to investigate the molecular mechanism and the effect of Saponin from Tupistra chinensis Baker (STCB) on the proliferation and apoptosis of ovarian cancer cells. To investigate the inhibitory effect of STCB on the proliferation of ovarian cancer cells, SKOV3 cells were cultured and the methyl thiazolyl tetrazolium assay was used. Flow cytometry was also used to analyze the cell cycle distribution and apoptotic rate. Ki-67, cyclin D1, cleaved caspase-3, cleaved caspase-9, β-catenin, and c-Myc protein expressions were detected by western blot. Ovarian cancer cells were treated with STCB and Wnt pathway activator lithium chloride (LiCl). These methods were also used to determine the proliferation, cell cycle distribution, and apoptosis of ovarian cancer cells. In STCB-treated group, the proliferation inhibition and apoptosis rate, the proportion of G0-G1 phase, and the expression level of cleaved caspase-3 and 9 of ovarian cancer cells were significantly increased. Similarly, the expression of Ki-67, cyclin D1, β-catenin, and c-Myc were significantly decreased (p less then .05). The results also showed that in STCB-LiCl-treated group, while the proliferation inhibition rate of ovarian cancer cells, the proportion of G0-G1 cells, the expression level of cleaved caspase-3 and 9, and the apoptosis rate (p less then .05) were significantly decreased, the expression level of Ki-67, cyclin D1, β-catenin, and c-Myc was significantly increased. STCB induced G0-G1 phase arrest, inhibited cell proliferation, and promoted apoptosis of ovarian cancer cells by inhibiting Wnt/β-catenin pathway.Aim Emergence of Extended-spectrum beta-lactamase (ESBL) producing with quinolone resistant (QR) pathogenic Enterobacteriaceae augmented the need to establish therapeutic options against them. Present study aimed towards determination of synergistic combination of eugenol with cefotaxime and ciprofloxacin to combat against this resistance and potentiation of antibacterial drugs by eugenol against these bacteria. Methods and results Synergistic interaction between eugenol and cefotaxime/ciprofloxacin (FICI 0.08 to 0.5) were observed among ESBL-QR bacteria using checkerboard assay. Approximately, 2-1024 fold MIC value reduction and 17-165030-fold Dose Reduction Index (DRI) strongly suggested synergistic interaction between eugenol and antibiotics. Cell viability assay showed reduction in log10 CFU per ml from 16.6 to 3.1 at synergistic concentration. Scanning electron microscopy further proved disruptive effect of eugenol on cell architecture. Eugenol and/or its combination also altered genes' expressions that imparted antibiotic resistance by ~1.6 to ~1226 folds. Conclusions Reduced doses of antibiotics, bacterial morphological alterations, efflux pump down regulation, porin over expression and beta lactamase gene inhibition of ESBL-QR bacteria by eugenol alone or in combination with cefotaxime/ciprofloxacin might have reversed antibiotic resistance profile of ESBL-QR bacteria. Significance and impact of study This study provided a molecular insight into action of eugenol and/with cefotaxime and ciprofloxacin, which might have potentiated antibiotic's activity against ESBL-QR bacteria.Objective To determine the effect of oversewing the transverse staple line after functional end-to-end stapled intestinal anastomoses (FEESA) on canine jejunal leakage pressures. Study design Experimental, ex vivo, randomized study. Sample population Jejunal segments from three adult canine cadavers. Methods Jejunal segments were harvested within 2 hours of euthanasia and anastomosed (24 jejunal segments per group, consisting of two segments per construct with n = 12/ group). Constructs were then randomly assigned to receive FEESA alone, FEESA + Cushing oversew, or FEESA + simple-continuous oversew of the transverse staple line with 3-0 polydioxanone. Results for initial leakage pressure (ILP) and maximal leakage pressure (MLP) and initial leakage location (LL) were compared between groups. Samuraciclib clinical trial Results Mean ILP was 1.8-fold higher for FEESA + Cushing oversew (62.4 ± 7.8 mm Hg) compared with FEESA alone and FEESA + simple-continuous oversew (P less then .001). Mean MLP were higher for both oversewn techniques compared with FEESA alone (P less then .