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These simulations show the stabilisation of predator and prey populations and/or the oscillation of these two species over time.This paper presents an investigation on the dynamics of a delayed diffusive competition model with saturation effect. We first perform the stability analysis of the positive equilibrium and the existence of Hopf bifurcations. It is shown that the positive equilibrium is asymptotically stable under some conditions, and that there exists a critical value of delay, when the delay increases across it, the positive equilibrium loses its stability and a spatially homogeneous or inhomogeneous periodic solution emerges from the positive equilibrium. Then, we derive the formulas for the determination of the direction of Hopf bifurcation and the properties of the bifurcating periodic solutions. Finally, some numerical simulations are performed to illustrate the obtained results.For the type reduction of general type-2 fuzzy PID controller is time consuming and the mathematical expression of general type-2 fuzzy PID controller is difficult to derived. So, a simplified general type-2 fuzzy PID (SGT2-FPID) controller is studied in this article. The SGT2-FPID controller adopts triangular function as the primary and secondary membership function. Then the primary membership degree of apex for the secondary membership degree will be applied to get the output of SGT2-FPID controller, which can reduce the computation complexity of general type-2 fuzzy controller type reduction. Furthermore, the mathematical expressions of SGT2-FPID controller, type-1 fuzzy PID controller and interval type-2 fuzzy PID controller are discussed. Finally, 4 plants are applied to demonstrate the effectiveness and robustness of SGT2-FPID controller. The simulation results show that when the plants have uncertainty in model structure, measurement and external disturbance, the SGT2-FPID controller can achieve better control performances in contrast to compared controllers.The objective was to explore variations of temperature distribution and coagulation zone size computed by a two-compartment radiofrequency ablation (RFA) model when including simultaneously reversible changes in the tissue electrical conductivity (σ) due to temperature and irreversible changes due to thermal coagulation. Two-compartment (tumor and healthy tissue) models were built and simulated. Reversible change of σ was modeled by a piecewise function characterized by increments of +1.5%/℃ up to 100 ℃, and a 100 times smaller value from 100 ℃ onwards. Irreversible changes of σ were modeled using an Arrhenius model. We assumed that both tumor and healthy tissue had a different initial σ value (as suggested by the experimental data in the literature) and tended towards a common value as thermal damage progressed (necrotized tissue). We modeled a constant impedance protocol based on 90 V pulses voltage and three tumor diameters (2, 3 and 4 cm). Computer simulations showed that the differences between both models were only 0.1 and 0.2 cm for axial and transverse diameters, respectively, and this small difference was reflected in the similar temperature distributions computed by both models. In view of the available experimental data on changes of electrical conductivity in tumors and healthy tissue during heating, our results suggest that irreversible changes in electrical conductivity do not have a significant impact on coagulation zone size in two-compartment RFA models.Background and Objective Voice disorders are pathological conditions that directly affect voice production. Computer based diagnosis may play a major role in the early detection and in tracking and even development of efficient pathological speech diagnosis, based on a computerized acoustic evaluation. The health of the Voice is assessed by several acoustic parameters. The exactness of these parameters is often linked to algorithms used to estimate them for speech noise identification. That is why main effort of the scientists is to study acoustic parameters and to apply classification methods that achieve a high precision in discrimination. The primary aim of this paper is for a meta-analysis on voice disorder databases i.e. SVD, MEEI and AVPD and machine learning techniques applied on it. Materials and Methods This field of study was systematically reviewed in compliance with PRISMA guidelines. A search was performed with a set of formulated keywords on three databases i.e. Science Direct, PubMed, and IEEE ervised techniques. It was also concluded that more work needs to be on voice pathology detection using AVPD database.We study a model for a network of synaptically coupled, excitable neurons to identify the role of coupling delays in generating different network behaviors. The network consists of two distinct populations, each of which contains one excitatory-inhibitory neuron pair. The two pairs are coupled via delayed synaptic coupling between the excitatory neurons, while each inhibitory neuron is connected only to the corresponding excitatory neuron in the same population. We show that multiple equilibria can exist depending on the strength of the excitatory coupling between the populations. We conduct linear stability analysis of the equilibria and derive necessary conditions for delay-induced Hopf bifurcation. We show that these can induce two qualitatively different phase-locked behaviors, with the type of behavior determined by the sizes of the coupling delays. Numerical bifurcation analysis and simulations supplement and confirm our analytical results. Our work shows that the resting equilibrium point is unaffected by the coupling, thus the network exhibits bistability between a rest state and an oscillatory state. This may help understand how rhythms spontaneously arise in neuronal networks.Statistical physics provides a useful perspective for the analysis of many complex systems; it allows us to relate microscopic fluctuations to macroscopic observations. Developmental biology, but also cell biology more generally, are examples where apparently robust behaviour emerges from highly complex and stochastic sub-cellular processes. Here we attempt to make connections between different theoretical perspectives to gain qualitative insights into the types of cell-fate decision making processes that are at the heart of stem cell and developmental biology. TBK1/IKKεIN5 We discuss both dynamical systems as well as statistical mechanics perspectives on the classical Waddington or epigenetic landscape. We find that non-equilibrium approaches are required to overcome some of the shortcomings of classical equilibrium statistical thermodynamics or statistical mechanics in order to shed light on biological processes, which, almost by definition, are typically far from equilibrium.

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