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t to maintain an appropriate index of suspicion when monitoring atypical visual field progression in a patient with glaucoma. In this case, imaging, subsequent biopsy, and a multi-specialty team were integral to this patient's diagnosis and management.

Mantle cell lymphoma is a rare aggressive subtype of non-Hodgkins B cell lymphoma. It typically presents with asymptomatic monoclonal lymphocytosis, lymphadenopathy or bulky extranodal disease. Mantle cell lymphoma rarely affects the central nervous system. We present two cases in which vision loss was the initial symptom of central nervous system involvement by the malignancy.

Both patients initially received high dose intravenous steroids with notable improvement in their vision.

Early detection and management of optic nerve infiltration by mantle cell lymphoma is essential as it improves visual outcomes and enables prompt management of the patient's systemic disease.

Early detection and management of optic nerve infiltration by mantle cell lymphoma is essential as it improves visual outcomes and enables prompt management of the patient's systemic disease.Lead (Pb), mercury (Hg) and fluoride (F) exposure during childhood is of concern owing to their toxicity. Also, evidence suggests that high and low exposure levels to manganese (Mn) and selenium (Se) during this vulnerable period are associated with an increased risk of adverse health effects. A reduced growth is associated with high Pb and F exposure; however, little is known about their impact on children's body size, and there is a lack of consensus on the effects of Hg, Mn, and Se exposure on children's anthropometric measures. This is particularly true for childhood metal co-exposures at levels relevant to the general population. We investigated the joint effects of exposure to a metal mixture (Pb, Mn, Hg, and Se in blood and F in plasma) on 6-11-year-old US children's anthropometry (n = 1,634). Median F, Pb, Mn, Hg, and Se concentrations were 0.3 μmol/L, 0.5 μg/dL, 10.2 μg/L, 0.3 μg/L, and 178.0 μg/L, respectively. The joint effects of the five metals were modeled using Bayesian kernel machine and linear regressions. Pb and Mn showed opposite directions of associations with all outcome measured, where Pb was inversely associated with anthropometry. For body mass index and waist circumference, the effect estimates for Pb and Mn appeared stronger at high and low concentrations of the other metals of the mixture, respectively. Our findings suggest that metal co-exposures may influence children's body mass and linear growth indicators, and that such relations may differ by the exposure levels of the components of the metal mixture.Intentional poisoning represents a serious risk to domestic and wild animals, and it can be an environmental and human health issue as well . This paper is a retrospective study, which covers a decade, based on animal poisoning cases and poisoned baits that were submitted for diagnostic examinations to the Veterinary Medical Research Institute for Piedmont, Liguria and the Aosta Valley (IZS-PLVA) in Liguria region. All data were collected through a passive surveillance system introduced in Italy by a decree of the Ministry of Health in January 2009. 43.2% of the animal poisoning cases were confirmed by toxicological analysis, whereas toxic agents were detected in 31.1% of the baits. The most affected animal species were dogs and cats, followed by synanthropic birds,. Only 4% of the total poisoning events analysed involved wild animals and cases of livestock poisoning were minimal. An increased number of cases in January, March, April and August was noticed, but no seasonal trend was detected. The most affected areas were the ones with the highest level of urbanization and population density. The major cause of the poisonings and the most common substances detected in the examined baits were anticoagulants whereas cholinesterase inhibitors, organochlorine pesticides and carbamates were detected in a minor number of cases. This study raises concerns about deliberate animal poisoning in ligurian region and highlights the necessity to fight this phenomenon as it endangers animals, humans and environment.The COVID-19 pandemic has influenced the lives of the global community, consequently, many parts of people's lives have been jeopardized. Therefore, there is a need to curb the spread of coronavirus. Accordingly, countries are enforcing partial or full-fledged lockdown to restrict all sorts of socialization. However, studies reported that people have despised the ordinances. Panobinostat chemical structure The study assessed the economic, societal, and psychological impacts of the pandemic and the practice of abiding by curfews by staying and working from home. One hundred thirty-three government, private, and self-employed workers have anonymously and voluntarily completed an online survey. The change in lifestyle associated with the pandemic influenced the working group economically, socially, emotionally, and spiritually. In addition to inflation in the prices of food and commodity, workers have spent unintended costs for the prevention of the COVID-19 such as hand sanitizer and facemask. Furthermore, staying home was unbearable for the majority of the respondents and led to stress, boredom, and confined feelings which forced them to leave their homes to liberate themselves. Nevertheless, flexibility in time management, reduced commuting, and being safe from COVID-19 made the lockdown advantageous for some of the respondents. Telecommuting is influenced by factors such as home suitability to work, availability of supplies, and the behavior of the workers. Home suitability to work and access to vital working facilities varied between government, private, and self-employed individuals. Government employees exceptionally lack appropriate homes and resources to work. Therefore, to minimize the impact of COVID-19 on people's life it is important to make timely adjustments to the enforced orders to make them more productive.Cowpea, Vigna unguiculata is a popular agricultural produce known as poor man's meat among Africans because it is very cheap and affordable. In spite of its importance, its infestation by cowpea seed bruchid, Callosobruchus maculatus has been a major constrain hindering its storage. Considering the high level of infestation of cowpea by C. maculatus and the high level of pollution caused by agricultural products, this research investigated the entomotoxicant effectiveness of rice husk, wheat husk and groundnut pod ash and powder in the control of cowpea beetle in storage. This study was carried out under laboratory condition of ambient temperature 28 ± 2 °C and 70 ± 5% relative humidity. The wastes (rice husk, groundnut pod and wheat husk) were pulverized separately and another portion was burnt to ashes at 525 °C. The powders and the ashes were analyzed for their proximate composition, phytochemical content (powders) and silica content (ashes). The powders and the ashes were tested at 0.1, 0.2, 0.3, 0.4 and 0.