Vittrupborre4931

ObjectiveEffects of drugs or immunotherapy on the quality of life of adult patients with allergic rhinitis（AR） were assessed using the rhinoconjunctivitis quality of life questionnaire（RQLQ）. MethodA total of 142 patients were included, including 37 patients receiving specific immunotherapy（SIT）（SIT group）. The remaining 105 patients received standardized drug treatment, and were divided into 87 cases in the receiving drug application instruction group（A1 group） and 18 cases in the non-receiving drug application instruction group（A2 group） according to whether or not receiving the drug application guidance group. According to whether or not receiving supervision of drug applications, they were divided into 33 cases of receiving drug application supervision group（B1 group） and 72 cases of non-receiving drug application supervision group（B2 group）. Using telephone follow-up, RQLQ was used to evaluate the patients 'daily activities, sleep, non-nasal-eye symptoms, nasal symptoms, eye symptoms, practical problems,mproved by improving medication guidance and publicity.ObjectiveTo investigate the effects of life events and emotional stress on short-term curative efficacy in adolescents with low-tone sudden deafness （LTSD）. MethodVarious psychological stress measures were conducted on adolescent patients with recently diagnosed LTSD before initiating treatment, and the follow-up hearing condition were also obtained after 3 months of treatment. find more Using logistic regression analysis, we identified the predictors of life stress and emotion symptoms of treatment response in these adolescent patients. ResultTreatment were effective in 103 cases and ineffective in 41 cases. The stress, depression and anxiety symptoms of the high-life events in the ineffective group were significantly higher than those in the effective group. The logistics regression analysis showed that life stress [OR（95%CI）=1.16（1.07-2.42） ] and depressive symptoms [OR（95%CI）=1.65（1.26-2.71） ] were significantly correlated with patients' prognosis after controlling for the duration of LTSD and the level of hearing loss before the treatment. ConclusionWe found life stress and depressive symptoms were the independent predictors of treatment response in adolescent patients with LTSD. Our results also highlighted that psychological intervention may be part of the primary treatment for LTSD in adolescents.ObjectiveTo explore the application value of anteromedial thigh flap（AMT） as alternative flap in repairing maxillofacial soft tissue defects. MethodSixty patients were scheduled to underwent anterolateral thigh flap（ALT） reconstruction. Preoperative CT angiography were conducted. Imaging workstations were used to locate perforator vessels in the anterolateral and anteromedial areas respectively. Four patients had no suitable perforator during the preparation of AMT flaps. In the same operation area, ALT flaps were prepared to reconstruct the defect according to the location of the perforator vessels in the anteromedial areas. ResultAll four AMT flaps survived uneventfully. Flap sizes ranged from 9 cm×6 cm to 7 cm×4 cm. The follow-up period ranged from 6 to 12 months, the functions of recipient and donor sites recovered well. ConclusionPreoperative CT angiography can improve the accuracy of the preparation of skin flap effectively. When no sizable perforator is available during harvest of the ALT flap, successful reconstruction can be achieved using the ipsilateral AMT flap.ObjectiveTo investigate the effects of nasal specific symptoms on chronic rhinosinusitis（CRS） with anxiety, depression and other psychological dysfunction and endoscopic surgery for the improvement of psychological dysfunction in patients with CRS. MethodThe Hamilton Anxiety Scale（HAMA）, Hamilton Depression Scale（HAMD） and the 22-Item Sino-Nasal Outcome Test（SNOT-22） were completed in 44 patients with CRS within one week before and 6 months after surgery. They were used to assess mental function and nasal specific symptoms. ResultAccording to the SNOT-22 score, patients with anxiety and depression mental dysfunction had more severe symptoms of dizziness, head and face pain and sleep disorders（P less then 0.01 or P less then 0.05）. After endoscopic sinus surgery, the scores of HAMD, HAMA and SNOT-22 in CRS patients were improved compared with preoperative（P less then 0.01）. ConclusionPatients with CRS have more common anxiety and depression. The specific symptoms of dizziness and head and face pain are significantly related to the psychological dysfunction of patients with CRS. Endoscopic sinus surgery can significantly alleviate the specific symptoms and mental dysfunction.ObjectiveTo observe the effect of hydrogen-rich saline on the concentration of nitric oxide in the nose, and to explore the mechanism of its treatment of allergic rhinitis. MethodTwenty patients with moderate to severe persistent allergic rhinitis were enrolled in a randomized, double-blind, self-controlled study. The nasal cavity was lavaged with hydrogen-rich normal saline and normal saline, and the nasal nitric oxide（nNO） value was tested weekly. ResultThe test value of nNO was correlated with the diagnosis and curative effect of allergic rhinitis. The difference of nNO test values before and after treatment of the two lavage fluids was statistically significant（P less then 0.01）. ConclusionHydrogen-rich saline lavage can cause nNO change in nasal cavity which may be used in the treatment of allergic rhinitis.ObjectiveThis thesis studies on epidemiological characteristics of patients with nasal bone fractures. MethodThis thesis retrospectively studies on 2 881 patients with nasal bone fractures. The characteristics, causes, and fracture types are collected and reviewed retrospectively. The type of nasal bone fracture is classified according to Fred's classification, and SPSS 25.0 software is used in statistical analysis. ResultThe sex ratio of nasal bone fracture between males and females is 2.44：1, male cases are obviously more than female cases. The group aged 19-29 years occupies the largest proportion, accounted for 35.54%. Traffic accident was the leading cause of the nasal bone fracture, accounting for 33.84%. The second cause was violent assault, 24.12% totally. The number of patients suffering nasal bone fractures combined with maxilla frontal process fractures is higher than that of simple nasal bone fractures. Type Ⅱ fracture is significantly more common in patients with other types nasal bone fractures.