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Areas for social activities, such as picnics, and intergenerational activities, as well as private spaces, were recommended. Throughout the garden, sensory features were suggested, incorporating the use of vision, smell, touch, and sound, such as through water features. Moreover, it was recommended that residents should be able to contribute to the delivery of the activities themselves, including through a café and a vegetable garden. Conclusions Family carers and staff considered that the garden would benefit from an intensive update to meet the needs of residents. This study therefore has practical implications for care home design, which are of even greater importance since the pandemic, as outdoor spaces were considered safer for care home visiting.

The purpose of this study is to fill the research gap regarding the influence of satisfaction with distance learning on the correlates of mental health during the COVID-19 pandemic.

An online cross-sectional study was conducted in February and March 2021, involving 4661 postsecondary students. Five validated instruments-PHQ-9 (depression), GAD-7 (anxiety), PSS-4 (stress), CD-RISC-10 (resilience) and SAT-5 (satisfaction with online study)-were used in the present study.

The correlations between anxiety, depression, and stress were so high that they were almost inextricably linked. Both satisfaction with online learning and psychological resilience were negatively correlated with anxiety, depression, and stress. Satisfaction with online learning was also negatively correlated with psychological resilience. Females showed higher levels of vulnerability to anxiety, depression, and stress, and exhibited lower levels of psychological resilience than males.

Home-based distance-learning during the COVID-19-induced lockdown had a significant impact on students' mental health. Low satisfaction with distance learning can lead to the development of anxiety and depression symptoms, increase stress, and decrease the psychological resilience of postsecondary students; therefore, it is critical that educational institutions focus on implementing interventions that promote students' satisfaction with distance learning, and their psychological resilience, to protect their mental health.

Home-based distance-learning during the COVID-19-induced lockdown had a significant impact on students' mental health. Low satisfaction with distance learning can lead to the development of anxiety and depression symptoms, increase stress, and decrease the psychological resilience of postsecondary students; therefore, it is critical that educational institutions focus on implementing interventions that promote students' satisfaction with distance learning, and their psychological resilience, to protect their mental health.Ever greater technological advances and democratization of digital tools such as computers and smartphones offer researchers new possibilities to collect large amounts of health data in order to conduct clinical research. Such data, called real-world data, appears to be a perfect complement to traditional randomized clinical trials and has become more important in health decisions. Due to its longitudinal nature, real-world data is subject to specific and well-known methodological issues, namely issues with the analysis of cluster-correlated data, missing data and longitudinal data itself. These concepts have been widely discussed in the literature and many methods and solutions have been proposed to cope with these issues. As examples, mixed and trajectory models have been developed to explore longitudinal data sets, imputation methods can resolve missing data issues, and multilevel models facilitate the treatment of cluster-correlated data. Nevertheless, the analysis of real-world longitudinal occupational health data remains difficult, especially when the methodological challenges overlap. The purpose of this article is to present various solutions developed in the literature to deal with cluster-correlated data, missing data and longitudinal data, sometimes overlapped, in an occupational health context. The novelty and usefulness of our approach is supported by a step-by-step search strategy and an example from the Wittyfit database, which is an epidemiological database of occupational health data. Therefore, we hope that this article will facilitate the work of researchers in the field and improve the accuracy of future studies.

Studies on the potential of smartphone apps for people with autism are currently increasing in number, given the large digital supply available and the benefits they offer. We analyzed the opinion of educators from Florence (Italy) and Granada (Spain) regarding the benefits and applicability of apps, frequency of their use, and the type of apps used for people with autism.

The study involved 1261 professionals, of whom 286 worked with apps, using a non-experimental quantitative design, descriptive and frequency statistics, parametric inferential analyses (Student's

and one-factor ANOVA), and calculation of the effect size (Cohen's

and eta squared) and intrafactorial correlations.

Statistically significant differences were observed in respect of city, sex, age, years of experience, place of work, and type of teacher. The teachers from Granada found more benefits and applicability in apps, and revealed a slightly higher usage than those from Florence.

It is an arduous but worthy task for professionals from schools and associations that work with people with autism to acquire the necessary knowledge to apply methodologies based on information and communication technology (ICT), as this will help achieve the integrated development of people with different capabilities.

It is an arduous but worthy task for professionals from schools and associations that work with people with autism to acquire the necessary knowledge to apply methodologies based on information and communication technology (ICT), as this will help achieve the integrated development of people with different capabilities.The purpose of this study was to investigate whether there is a gender-specific difference in the indirect effect of perceived coaching behaviors of Taekwondo Poomsae athletes on performance mediated by basic psychological needs. To this end, a survey was conducted to collect data from 474 Taekwondo Poomsae athletes (male = 285). Based on the collected data, analysis of basic descriptive statistics and confirmatory factor analysis were performed, and PROCESS was used to test the proposed model of multi mediated moderation. For female athletes, there was an indirect effect of controlling coaching behaviors resulting in performance improvement mediated by autonomy, but this effect was not observed in male athletes. The findings of this study indicate that different mental conditioning strategies should be applied in consideration of athletes' gender to improve coaches' methods of instruction and ultimately improve performance in Taekwondo Poomsae.As the portion of older adults in the population in rural areas of South Korea exceeds 20%, the importance of health-related quality of life is increasing. The aim of the study was to examine the health-related quality of life through the ecological model and its basic determining factors for older adults. The study was conducted on 184 respondents aged 65 and over living in rural areas of South Korea. The measurements were health-related quality of life, health care service needs, sleep quality, social support, and personal characteristics. The collected data were tested using descriptive, t-test, ANOVA, and hierarchical multiple regression. The results showed that older adults in rural areas experienced a low quality of life. Religion, having a helper, and social support were significantly related to health-related quality of life in older adults. This directly shows that the government should make efforts to build a social support system to improve the gap between urban and rural areas. To improve the health-related quality of life of older adults in rural areas, it would be helpful to increase physical activity and to form a community, leading to a social network.The increasing use of pesticides in intensive agriculture has had a negative impact on human health. It was widely demonstrated how pesticides can induce different genetic and epigenetic alterations associated with the development of different diseases, including tumors and neurological disorders. Therefore, the identification of effective indicators for the prediction of harmful pesticide exposure is mandatory. In this context, the aim of the study was to evaluate the modification of hsa-miR-199a-5p expression levels in liquid biopsy samples obtained from healthy donors and farm workers with chronic exposure to pesticides. For this purpose, the high-sensitive droplet digital PCR assay (ddPCR) was used to detect variation in the expression levels of the selected microRNA (miRNA). Gefitinib-based PROTAC 3 molecular weight The ddPCR analyses revealed a significant down-regulation of hsa-miR-199a-5p observed in individuals exposed to pesticides compared to control samples highlighting the good predictive value of this miRNA as demonstrated by statistical analyses. Overall, the obtained results encourage the analysis of miRNAs as predictive biomarkers of chronic pesticide exposure thus improving the current strategies for the monitoring of harmful pesticide exposure.Given the scarcity of data on diabetes prevalence and associated risk factors among women in rural Nepal, we aimed to examine this, using glycated hemoglobin (HbA1c) as a diagnostic tool. A cross-sectional survey addressing reproductive health and non-communicable diseases was conducted in 2012-2013 among non-pregnant, married women in Bolde, a rural district of Nepal. HbA1c ≥ 6.5% (48 mmol/mol) was used as diagnostic criterion for diabetes, a cut-off of 7.0% (53 mmol/mol) was used to increase the specificity. HbA1c was measured in 757 women (17-86 years). The prevalence of diabetes and prediabetes was 13.5% and 38.5%, respectively. When using 7.0% as a cut-off, the prevalence of diabetes was 5.8%. Aging, intake of instant noodles and milk and vegetarian food (ns) were associated with increased risk for diabetes. Waist circumference was higher among women with diabetes, although not significant. The women were uneducated (87.6%), and only 12% had heard about diabetes. In conclusion, we observed a higher prevalence of diabetes and prediabetes than anticipated among rural, Nepalese women. The increased risk was mainly attributed to dietary factors. In contrast to most previous studies in Nepal, we used HbA1c as diagnostic criterion.Although it is assumed that loneliness in one relationship might put one at risk of experiencing loneliness in another relationship, this association has rarely been examined as such. In this longitudinal study, we examined the associations between peer- and parent-related loneliness in a sample of 3391 adolescents across three waves (Mage Wave 1 = 14.53; 59.3% female). Using random intercept cross-lagged panel models, parent- and peer-related loneliness were found to be stable over time and were concurrently related to each other. Moreover, the state of peer-related loneliness predicted the state of parent-related loneliness one year later. Thereby, the current study provides limited evidence of a carry-over effect between relation-specific types of loneliness.

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