Delacruzochoa9727

First, we propose to utilize the medical knowledge graph as an internal information of a patient by constructing sequential patient graphs. These graphs not only carry the historical information from the EHR but also infuse with domain knowledge. Then we design a robust diagnosis prediction model based on a spatial-temporal graph convolutional network. The proposed model extracts meaningful features from sequential graph EHR data effectively through multiple spatial-temporal graph convolution units to generate robust patients' representations for accurate diagnosis predictions. We evaluate the performance of GNDP against a set of state-of-the-art methods on two real-world medical data sets, the results demonstrate that our methods can achieve a better utilization of knowledge graph and improve the accuracy on diagnosis prediction tasks.

To investigate via computer simulation, an optimised tube voltage (kVp) range for caesium iodide (CsI)-based digital radiography (DR) of the abdomen, pelvis and lumbar spine.

Software capable of simulating abdomen, pelvis and spine radiographs was used. Five evaluators graded clinical image criteria in images of 20 patients at tube voltages ranging from 60 to 120 kVp in 10 kVp increments. These criteria were scored blindly against the same patient reconstructed at a specific reference kVp. Linear mixed effects analysis was used to evaluate image scores for each criterion and test for statistical significance.

Score was dependent on tube voltage and image criteria; both were statistically significant. All criteria for all anatomies scored very poorly at 60 kVp. Scores for abdomen, pelvis and spine imaging peaked at 70, 70 and 100 kVp, respectively, but other kVp values were not significantly poorer.

Results indicate optimum tube voltages of 70 kVp for abdomen and pelvis (with an optimum range 70-120 kVp), and 100 kVp (optimum range 80-120 kVp) for lumbar spine.

There are no recommendations for optimised tube voltage parameters for DR abdomen, pelvis or lumbar spine imaging. This study has investigated and recommended an optimal tube voltage range.

There are no recommendations for optimised tube voltage parameters for DR abdomen, pelvis or lumbar spine imaging. This study has investigated and recommended an optimal tube voltage range.

To determine the toxicity reduction required to justify the added costs of MRI-guided radiotherapy (MR-IGRT) over CT-based image guided radiotherapy (CT-IGRT) for the treatment of localized prostate cancer.

The costs of delivering prostate cancer radiotherapy with MR-IGRT and CT-IGRT in conventional 39 fractions and stereotactic body radiotherapy (SBRT) 5 fractions schedules were determined using literature values and cost accounting from two institutions. Gastrointestinal and genitourinary toxicity rates associated with CT-IGRT were summarized from 20 studies. Toxicity-related costs and utilities were obtained from literature values and cost databases. Markov modeling was used to determine the savings per patient for every 1% relative reduction in acute and chronic toxicities by MR-IGRT over 15 years. The costs and quality adjusted life years (QALYs) saved with toxicity reduction were juxtaposed with the cost increase of MR-IGRT to determine toxicity reduction thresholds for cost-effectiveness. One way sicity reduction alone.Timely, accurate diagnosis of upper extremity vascular pathology is critical for successful clinical and surgical management. Although the vast majority of upper extremity vascular injury is due to trauma, physicians in the emergency setting, including radiologists, must be familiar with vascular lesions from iatrogenic injury, thromboembolic disease, vascular malformations, and vasculitis. Non-invasive diagnostic imaging with multidetector CT (MDCT) angiography is often employed in the emergency department to evaluate patients with suspected vascular pathology of the upper extremity. Maximum intensity projection and volume rendering technique are two methods that are useful for evaluating vasculature. In addition, dual-energy MDCT is useful in that it allows for the generation of iodine-selective images and bone subtracted images. These techniques can be used to create images that simulate catheter angiograms. In this article, we will discuss the role of MDCT angiography in the diagnosis and management of emergent non-traumatic vascular lesions of the upper extremity.

To investigate the clinical and radiological features of immune checkpoint inhibitor-related pneumonitis (ICI-P), a rare but serious pulmonary complication of cancer immunotherapy and to evaluate key differences between lung cancer (LC) and non-LC patients.

247 patients (LC,

= 151) treated with ICI for malignancies were retrospectively screened in a single institute. read more The number of patients, history of other immune-related adverse events (irAE), the onset, serum KL-6 levels, and chest CT features (types of pneumonitis, symmetry, laterality, location) were recorded for the ICI-P population and compared for LC and non-LC groups.

ICI-P was identified in 26 patients in total (LC,

= 19; non-LC,

= 7). The incidence of other irAE was significantly higher in ICI-P group (63%) compared with patients without ICI-P (34%) (

= 0.0056). An earlier onset of ICI-P was recorded in LC (78 days) compared to non-LC patients (186 days) (

= 0.0034). Serum KL-6 was significantly elevated only in the non-LC group wstory of other irAE can be more frequently observed. Differences in disease onset and radiological patterns between LC and non-LC patients might be helpful to make a diagnosis of ICI-P; however, longitudinal observation of chest CT scans is advised to observe the pneumonitis activity irrespective of cancer types.The aim of this review is to provide an overview of different functional cardiac CT techniques which can be used to supplement assessment of the coronary arteries to establish the significance of coronary artery stenoses. We focus on cine-CT, CT-FFR, CT-myocardial perfusion and how developments in machine learning can supplement these techniques.E-cigarettes (eCig) are being considered as an alternative to quit cigarette smoking while their long-term effect on lung pathophysiology are unknown. Maternal eCig-vaping may be promoted and considered as a safer cigarette smoking-replacement during pregnancy thus needing further assessment. Using murine models of in utero vaping and allergic asthma with complementary in vitro experiments we tested whether maternal eCig vaping enhances features of allergic asthma in offspring. Female BALB/c mice were exposed to either eCig vapor (± nicotine) or room air. Female offspring from these mothers were subjected to an ovalbumin (OVA)-induced allergic asthma model. Lung function and airway inflammation was assessed. Tissues were histologically assessed with H&E, Periodic Acid-Schiff and Masson's trichrome. Mitochondrial homeostasis protein expression was measured using immunohistochemistry while human airway smooth muscle (ASM) and Beas-2B cells were used to further measure cellular function and mitochondrial respiration.