Munchhunt1046

An increasing trend was observed in the prevalence of Toxoplasma oocysts with increasing latitude (41-56°), decreasing longitude (0-40°) and increasing relative humidity (≥76%). Loop-mediated isothermal amplification and polymerase chain reaction methods revealed the highest and lowest prevalence rates, respectively, in the detection of Toxoplasma oocysts. Awareness of the health authorities and people about Toxoplasma prevalence in the soil of public places and its risk factors is of great importance to developing effective strategies to prevent infection.

Human papillomavirus (HPV) infection is associated with multiple types of cancer, but the evidence has not yet been fully elucidated in bladder cancer.

Frozen tissue samples collected from 146 patients aged 32 to 89 years-old with bladder cancer pathological diagnosis between 2015 and 2019 were analyzed. HPV genotyping and integration status determination were performed by capture-based next generation sequencing. Statistical analysis of HPV type distributions was performed according to stage, grade, gender and age group of patients.

Mean age of 146 patients was 66.64 ± 10.06 years and 83.56% were male. Overall HPV infection rate was 28.77% (37.5% in female and 27% in male), with 11.90% HPV integration events. Among them, 17.12% single and 11.65% co-infections were observed. HPV18 (24.66%) was the most prevalent genotype, followed by HPV33, 16, 39. All HPV were European lineage (A). HPV16 was more prevalent in female (p=0.04).

HPV infection may contribute a causative role both in men and women with bladder cancer. selleck HPV18, followed by HPV 33, 16 and 39 genotypes potentially represent the predominant oncogenic risk types of bladder carcinogenesis.

HPV infection may contribute a causative role both in men and women with bladder cancer. HPV18, followed by HPV 33, 16 and 39 genotypes potentially represent the predominant oncogenic risk types of bladder carcinogenesis.

There is a lack of knowledge about hormonal and anthropometric changes in women with polycystic ovary syndrome (PCOS) after the menopause.

This work aimed to study reproductive hormones and anthropometry in women with PCOS older than 80 years.

This prospective cohort study was conducted at a university hospital.

A well-defined cohort of women with PCOS, previously examined in 1987 and 2008 (21 years) was reexamined in 2019 (11 years). Of the original cohort (n = 37), 22 women were still alive and 21 (age range, 72-91 years) participated. Comparisons were made with age-matched controls (n = 55) from the original control cohort (body mass index [BMI] similar to PCOS women). The results were compared with results from 1987 and 2008.

Hormonal measurements and a physical examination were performed.

Follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, sex hormone-binding globulin (SHBG), free androgen index (FAI), hirsutism score, BMI, and waist to hip ratio (WHR) were measured.

At mean age 81 years, FSH levels were lower in women with PCOS (50 vs 70 IU/L) who were still more hirsute than controls (33% vs 4%). No differences were found in FAI, testosterone, SHBG or LH levels, BMI, or WHR. From perimenopausal age until the present age, levels of testosterone and FAI continued to decline in women with PCOS. SHBG levels continued to increase with age. FSH had not changed over time during the last 11 years.

Women with PCOS at age 72 to 91 had lower FSH levels, remained clinically hyperandrogenic, and had similar FAI and body composition as controls.

Women with PCOS at age 72 to 91 had lower FSH levels, remained clinically hyperandrogenic, and had similar FAI and body composition as controls.

Whether type-specific human papillomavirus (HPV) infection influences the risk of acquiring infections with other HPV types is unclear. We studied concurrent HPV infections in 17-year-old girls from two birth cohorts; the first vaccine-eligible cohort in Norway and a pre-vaccination cohort.

Urine samples were collected and tested for 37 HPV genotypes. This study was restricted to unvaccinated girls from the pre-vaccination cohort (n=5245) and vaccinated girls from the vaccine-eligible cohort (n=4904). Risk of HPV infection was modelled using mixed-effect logistic regression. Expected frequencies of concurrent infection with each pairwise combination of the vaccine types and high-risk types (6/11/16/18/31/33/35/39/45/51/52/56/58/59) were compared to observed frequencies.

Infection with multiple HPV types was more common among unvaccinated girls than vaccinated girls (9.2% vs. 3.7%). HPV33 and HPV51 was the only HPV-pair that was detected together more often than expected among both unvaccinated (p=0.002) and vaccinated girls (p<0.001). No HPV-pairs were observed significantly less often than expected.

HPV33 and HPV51 tended to be involved in co-infection among both unvaccinated and vaccinated girls. The introduction of HPV vaccination does not seem to have had an effect on the tendency of specific HPV types to cluster together.

HPV33 and HPV51 tended to be involved in co-infection among both unvaccinated and vaccinated girls. The introduction of HPV vaccination does not seem to have had an effect on the tendency of specific HPV types to cluster together.The use of feathers as noninvasive physiological measurements of biomarkers in poultry research is expanding. Feather molting patterns and growth rates, however, are not well described in domestic poultry. These parameters could influence the measurement of these biomarkers. Therefore, the objective of this study was to describe the juvenile primary feather molting patterns and feather growth rates for domestic turkeys. The 10 primary wing feathers of 48 female turkeys were measured weekly from week 1 (0 d of age) to week 20. Feathers were manually measured, and the presence or absence of each primary feather was recorded weekly. Generalized linear mixed models were used to investigate if feather growth differed between the primary feathers. The molting of the juvenile primary feathers followed a typical descending pattern starting with P1 (5 wk of age), while P9 and P10 had not molted by the end of the study (20 wk of age). The average feather growth rate was 2.4 cm/wk, although there was a significant difference between the 10 primary feathers (P less then 0.