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(PsycInfo Database Record (c) 2020 APA, all rights reserved).To clarify the involvement of the cerebellum in impaired sensory integration in patients with schizophrenia, 52 first-episode patients with schizophrenia and 52 age- and sex-matched healthy controls underwent a verified sensory integration imaging task to examine the whole-brain dysfunction underlying impaired sensory integration. The familiality of cerebellar activation when integrating sensory stimuli was investigated in 25 siblings of the patients with schizophrenia, while the heritability of cerebellar activation was estimated in 56 monozygotic twins and 56 dizygotic twins. In addition, the functional connectivity between the cerebellum and the remaining regions of the whole brain was explored with psychophysiological interaction analysis. Relative to healthy controls, patients with schizophrenia showed reduced cerebellar activation when performing the sensory integration task in the whole-brain analysis. This reduced cerebellar activation was also found in the siblings of patients with schizophrenia, but to a lesser extent compared with schizophrenia patients. Cerebellar activation during sensory integration was also found to be significantly heritable. Furthermore, dysconnectivity within the cerebellum was found in patients with schizophrenia when integrating auditory and visual stimuli. These findings highlight the role of cerebellar dysfunction in the pathophysiology of schizophrenia symptoms and its potential role as an endophenotype of schizophrenia spectrum disorders. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Most people hold that it is wrong to sacrifice some humans to save a greater number of humans. Do people also think that it is wrong to sacrifice some animals to save a greater number of animals, or do they answer such questions about harm to animals by engaging in a utilitarian cost-benefit calculation? Across 10 studies (N = 4,662), using hypothetical and real-life sacrificial moral dilemmas, we found that participants considered it more permissible to harm a few animals to save a greater number of animals than to harm a few humans to save a greater number of humans. This was explained by a reduced general aversion to harm animals compared with humans, which was partly driven by participants perceiving animals to suffer less and to have lower cognitive capacity than humans. Autophagy inhibitor However, the effect persisted even in cases where animals were described as having greater suffering capacity and greater cognitive capacity than some humans, and even when participants felt more socially connected to animals than to humans. The reduced aversion to harming animals was thus also partly due to speciesism-the tendency to ascribe lower moral value to animals due to their species-membership alone. In sum, our studies show that deontological constraints against instrumental harm are not absolute but get weaker the less people morally value the respective entity. These constraints are strongest for humans, followed by dogs, chimpanzees, pigs, and finally inanimate objects. (PsycInfo Database Record (c) 2020 APA, all rights reserved).Social inequalities limit important opportunities and resources for members of marginalized and disadvantaged groups. Understanding the origins of how children construct their understanding of social inequalities in the context of their everyday peer interactions has the potential to yield novel insights into when-and how-individuals respond to different types of social inequalities. The present study examined whether children (N = 176; 3- to 8-years-old; 52% female, 48% male; 70% European American, 16% African American, 10% Latinx, and 4% Asian American; middle-income backgrounds) differentiate between structurally based inequalities (e.g., based on gender) and individually based inequalities (e.g., based on merit). Children were randomly assigned to a group that received more (advantaged) or fewer (disadvantaged) resources than another group due to either their groups' meritorious performance on a task or the gender biases of the peer in charge of allocating resources. Overall, children evaluated structurally based inequalities to be more unfair and worthy of rectification than individually based inequalities, and disadvantaged children were more likely to view inequalities to be wrong and act to rectify them compared to advantaged children. With age, advantaged children became more likely to rectify the inequalities and judge perpetuating allocations to be unfair. Yet, the majority of children allocated equally in response to both types of inequality. The findings generated novel evidence regarding how children evaluate and respond to individually and structurally based inequalities, and how children's own status within the inequality informs these responses. (PsycInfo Database Record (c) 2020 APA, all rights reserved).Congruence hypotheses play a major role in many areas of psychology. They refer to, for example, the consequences of person-environment fit, similarity, or self-other agreement. For example, are people psychologically better adjusted when their self-view is in line with their reputation? A valid statistical approach that can be applied to investigate congruence hypotheses of this kind is quadratic Response Surface Analysis (RSA) in which a second-order polynomial model is fit to the data and appropriately interpreted. However, quadratic RSA does not allow researchers to investigate more precise expectations about a congruence effect. Do the data support an asymmetric congruence effect, in the sense that congruence leads to the highest (or lowest) outcome, but incongruence in one direction (e.g., self-view exceeds reputation) affects the outcome differently than incongruence in the other direction (e.g., self-view falls behind reputation)? Is there a level-dependent congruence effect, such that the amount of congruence is more strongly related to the outcome variable for some levels of the predictors (e.g., high self-view and reputation) than for others (e.g., low self-view and reputation)? Such complex congruence hypotheses have frequently been suggested in the literature, but they could not be investigated because an appropriate statistical approach has yet to be developed. Here, we present analytical strategies, based on third-order polynomial models, that enable users to investigate asymmetric and level-dependent congruence effects, respectively. To facilitate the correct application of the suggested approaches, we provide respective step-by-step guidelines, corresponding R syntax, and illustrative analyses using simulated and real data. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

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