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Clinical importance lies in distinguishing hibernoma from other benign and malignant breast neoplasms, as well as inflammatory conditions that come into the histologic or radiologic differential. Hibernoma is not currently classified as a non-endocrine tumor related to MEN1, but this association could be not fortuitous for the linkage between modification of Menin protein function and pathogenesis of hibernomas.

Our case deserves extraordinary attention because, not only it's a case of MEN1 syndrome associated with hibernoma, but in the context of this lesion there are multiple micro-foci of infiltrating lobular carcinoma.

Our case deserves extraordinary attention because, not only it's a case of MEN1 syndrome associated with hibernoma, but in the context of this lesion there are multiple micro-foci of infiltrating lobular carcinoma.

Laparoscopic surgeries are becoming more popular in many surgical procedures particularly in pediatric age group. The physical responses and hemodynamic changes that occur during laparoscopic surgery differ between adults and pediatrics.

We report a sudden hemodynamic instability and abrupt ECG changes associated with pneumomediastinum (PM) during laparoscopic Nissen fundoplication surgery in a 19 months old boy who had gastro-esophageal reflux disease. Procedure was converted to open surgery and all parameters were spontaneously returned back to normal values. The patient was successfully extubated then transferred to intensive care unit (ICU) for close monitoring. He had uneventful post-operative course where PM has been completely resolved in the repeated chest x-ray.

Pneumomediastinum (PM) occurs when air escape into the mediastinum. This air might reach the pericardium causing hemodynamic and electrophysiological changes. It is one of the reported complications that might occur during laparoscopic surgery, however isolated PM usually resolve spontaneously without any intervention. Etiology and possible contributing factors were discussed.

Pneumoperitonium leads to different hemodynamic changes during laparoscopic surgery in pediatric population compared to adults. Decreasing the insufflation pressure and patient's re-positioning might make continuing laparoscopy safe. However, surgeon must be willing to convert to open surgery to prevent any further complications.

Pneumoperitonium leads to different hemodynamic changes during laparoscopic surgery in pediatric population compared to adults. Decreasing the insufflation pressure and patient's re-positioning might make continuing laparoscopy safe. However, surgeon must be willing to convert to open surgery to prevent any further complications.

Schwannomas are benign lesions arising from the nerve sheath, commonly located in the head and neck. Intraoral schwannomas mostly occur in tongue and lips and are rarely located in the soft palate.

We describe the diagnostic assessment and treatment of 18-year old male presenting with an intraoral mass on the soft palate.

The treatment of choice in peripheral nerve sheath tumors is conservative resection and due to location and impairment, reconstruction. Secondary healing of soft palate defects is rarely described in the literature.

With this case report, we demonstrate the feasibility of secondary healing after resection of a 3,0 × 1,9 × 2,1 cm schwannoma in the soft palate, resulting in no postoperative impairments, especially due to velopharyngeal function in a follow-up period of 2 months.

With this case report, we demonstrate the feasibility of secondary healing after resection of a 3,0 × 1,9 × 2,1 cm schwannoma in the soft palate, resulting in no postoperative impairments, especially due to velopharyngeal function in a follow-up period of 2 months.

Bronchiectasis is chronic infectious and inflammatory disease that results in irreversible thickening and dilatation of bronchi, and significant lung function decline in children. Prompt early diagnosis and multidisciplinary intervention is crucial to control recurrent exacerbation and preserve lung function.

We present a case of pediatric bronchiectasis in a 10-year-old female who presented with a complaint of intermittent wet cough of 5 weeks' duration associated with low grade intermittent fever, shortness of breath, easy fatigability and loss of appetite. JNJ-64264681 manufacturer Left pneumonectomy was done through left posterolateral thoracotomy and she was discharged home in good condition.

Recurrent lower tract air way infections are the most common causes of pediatric bronchiectasis followed by primary immune deficiency, primary ciliary dyskinesia, foreign body aspiration and airway structural abnormalities. It is crucial to equip health care professionals with adequate knowledge about the disease as most pediatric pati for those with recurrent infection despite adequate medical therapy.

We present a case series of three patients with advanced cervical cancer who either refused the standard of care systemic or chemoradiation treatment or did not benefit from it.

We treated patients with isolated hypoxic pelvic perfusion (HPP).

Two patients achieved complete clinicopathologic response and one patient required surgical excision of the necrotic residual mass containing no viable cancer cells. There were no long-term systemic or local side effects. All patients are cancer free for up to 15 years after conclusion of treatment.

HPP is an effective option for treatment of advanced cervical cancer that generates rapid and onlasting remissions at low side effects. Gynecologic oncologists shall be aware of HPP to facilitate wider adaption of our technique.

HPP is an effective option for treatment of advanced cervical cancer that generates rapid and onlasting remissions at low side effects. Gynecologic oncologists shall be aware of HPP to facilitate wider adaption of our technique.

Polyorchidism is a rare congenital malformation with about 200 cases reported in literatures. Triorchidism and left side occurrence are the most common presentation. This case report was aimed to report the rare presentation of polyorchidism which was on the right side and along with incarcerated inguinal that make it by far the least encountered presentation. The intraoperative management for the polyorchidism was an issue of dilemma but adult type can be excised safely.

A 43 year old farmer presented with right side inguino-scrotal mass and recent failure to reduce to abdomen. He used to have pain lower abdominal pain with slight pressure since childhood but didn't get any medical evaluation. He has completed his family number and didn't complain any sexual problem. Physical examination showed that there was non-tender irreducible soft right side inguino-scrotal mass. The right side testis was not appreciated.

Triorchidism is one of the commonly occurring variant of supernumerary testes that diagnosed incidentally during investigations or interventions for other pathologies.

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