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Sacituzumab govitecan in vitro , a rogue band of Republican Party operatives has attracted considerable media attention, and the Twitter wrath of President Trump, with a series of negative advertisements attacking the incumbent. The Lincoln Project strategy demonstrates how social and cultural conservatives are attracted to a particular aesthetic, prompted by their psychological attraction to rhetorical forms that are threat-oriented, clear, efficient, hyperbolic, emotional, and authoritative.With so much media attention on the presidential campaign, how do voters learn about candidates and elections for other offices? On local TV news, political ads create the reality of local races-a reality that is not meant to inform voters but to persuade them. Voters are left to their own devices to fill in the space between what the ads say-the bought reality-and what political stories used to cover.In this year of pandemic, it seems assured that a record number of citizens will choose to vote by mail. But approval of this method of voting appears increasingly divided along partisan lines, thanks in part to President Trump's declamations. Evidence from the presidential primaries held earlier this year indicates that allegiance to the president, as well as relative lack of concern about the COVID-19 virus, made voters less likely to choose to vote by mail.For decades, Republicans and American conservatives have cultivated and employed public distrust in government to garner strategic benefits. But officeholders have typically behaved with restraint in running for reelection, limiting their pursuit of electoral self-interest at the expense of the political system they are sworn to "preserve, protect, and defend." President Trump has shown little interest in such restraint, and his attacks on the electoral process could produce grave social and political consequences in the aftermath of the 2020 election.In a year marked by a global pandemic, economic collapse, and social unrest, the most striking feature of presidential polling thus far is its consistency. The hyperpartisanship of this polarized era of American politics has made most voters impervious to changing conditions. This raises serious questions about the utility of elections as means of democratic accountability.The article focuses on scientific disagreement about the use of statin-related drugs in the prevention of cardiovascular events. The study forms part of an exploration of the broader principle of research polarization, foremost in medicine. The hypothesis is that statin-positive and statin-critical researchers publish in different committed central journals, and that they are financially supported by different dedicated corporate sources. Methodologically we use Web of Science (WoS) analytic tools to perform publication analysis of a time series covering 1998-2018 in three seven-year windows. For each window data is captured based on sets of known statin-positive and statin-critical articles and researchers, and their primary and secondary co-authors. Standard deviation is used as a focused normalization and visual instrument together with Spearman's correlation coefficient in order to compare frequency distributions of statin-positive and critical journal and sponsor articles. Z-test p-values are used to assa and Pfizer. In conclusion, the initial hypothesis about dedicated journals and sponsors was entirely substantiated at the general topical level and at the journal level of research disagreement, but not at sponsor level. Distinct dedicated journals were extracted separately from the 2 divergent statin positions. Since the WoS coverage of sponsor data 1998-2004 was sporadic sponsor data are analyzed from 2005. Only from 2012 the WoS sponsor coverage of the topic is consistently at 60%.The area of fluorinated amino acid synthesis has seen rapid growth over the past decade. As reports of singly fluorinated natural amino acid derivatives have grown, researchers have turned their attention to develop methodology to access complex proteinogenic examples. A variety of reaction conditions have been employed in this area, exploiting new advances in the wider synthetic community such as photocatalysis and palladium cross-coupling. In addition, novel fluorinated functional groups have also been incorporated into amino acids, with SFX and perfluoro moieties now appearing with more frequency in the literature. This review focuses on synthetic methodology for accessing complex non-proteinogenic amino acids, along with amino acids containing multiple fluorine atoms such as CF3, SF5 and perfluoroaromatic groups.The COVID-19 pandemic has caused a number of fundamental changes in different societies, and can therefore be understood as creating "disjuncture" in our lives. Disjuncture is a concept proposed by adult educator Peter Jarvis to describe the phenomenon of what happens when an individual is confronted with an experience that conflicts with her/his previous understanding of the world. #link# Faced with a situation that creates disjuncture, the person is compelled to find new knowledge and new ways of doing things; i.e., he/she must embark on a learning process. The recent introduction of social distancing as a measure aiming to reduce transmission of the COVID-19 virus has dramatically changed people's behaviour, but this measure does not only have preventive and desirable effects. There is an associated risk for increased isolation among the older generations of the population, as well as a change in intergenerational relationships. Although the current pandemic (as disjuncture) may potentially initiate major learning processes in the human collective, we should remember that disjuncture is often theorised within neutral, or even positive, contexts. In a context of fear, however, learning may result in a narrowing of mindsets and a rejection of collective efforts and solidarity between generations. In terms of the types of learning triggered by the current pandemic (as disjuncture), one problem is non-reflective learning, which primarily occurs on a behavioural level. We need to recognise this and engage in reflective learning if we are to make the choices that will lead to a society that is worth living in for all generations. Our goal must be to learn to be a person in a post-pandemic society.