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Margin infiltration on the surgical specimen negatively affected the outcome, whereas no correlation was identified with

mutation status.

An adequate margin positively affects survival.

mutation status does not affect patient outcome.

An adequate margin positively affects survival. IDH mutation status does not affect patient outcome.The coronavirus disease 2019 (COVID-19) pandemic has drastically altered health care delivery and utilization. The field of otolaryngology in particular has faced distinct challenges and an increased risk of transmission as day-to-day procedures involve intimate contact with a highly infectious upper respiratory mucosa. While the difficulties for physicians have been thoroughly discussed, the unique challenges of patients have yet to be considered. In this article, we present challenges for patients of otolaryngology that warrant thoughtful consideration and propose solutions to address these challenges to maintain patient-centered care both during and in the aftermath of the COVID-19 pandemic.

The purpose of this study was to reveal the relationship between rapid weight loss and injury patterns during the training of elite wrestlers, expected to represent South Korea.

Since 2019, data for elite wrestlers have been collected prospectively by the Korean Training Center. TH-257 The data were stratified by sex, wrestling style, weight class, injury location, injuries during the weight-loss period, and weight loss method. The χ2 test was used to compare groups. The risk of injury was indicated by the Poisson rate with a 95% confidence interval (95% CI).

There were 120 male Greco-Roman, 120 male freestyle, and 100 female freestyle wrestling. The mean weight loss among wrestlers was 5.52 (±1.44) kg, and the mean duration of weight loss was 7.96 (±3.31) days. In general, all wrestlers used similar weight loss methods. We recorded 914 injuries in 340 athletes. Wrestlers had significantly higher injury rates during weight loss periods than during other periods of training (23.18 VS 11.93; p <0.001). Most injuries occurred in the lower extremities (38.0%), followed by the upper extremities (25.9%), trunk (24.8%), and the head and neck area (11.3%). The injury severity was significantly influenced by sex, wrestling style, and weight class.

Rapid weight loss is related to the incidence of sports injuries in wrestlers. Most injuries occur during rapid weight loss periods in South Korean elite wrestlers. Moreover, the injury site and injury severity depend on sex, wrestling style, and weight class.

Rapid weight loss is related to the incidence of sports injuries in wrestlers. Most injuries occur during rapid weight loss periods in South Korean elite wrestlers. Moreover, the injury site and injury severity depend on sex, wrestling style, and weight class.

Most studies focused on the application of intracavitary electrocardiogram (IC-ECG) location in superior vena cava access catheterization, this study aimed to explore the effect of IC-ECG for tip location of femoral vein catheters in chemotherapy patients with superior vena cava obstruction (SVCO).

A total of 158 patients placed catheters through superficial femoral vein from July 2016 to May 2019 were enrolled in the randomized controlled study. The patients were divided into two groups by envelope lottery method X-ray location was used in the control group (

 = 79); IC-ECG location was used in the observation group (

 = 79). The catheters should be located at or near the inferior vena cava (IVC)-right atrium (RA) junction (above the level of diaphragm within the IVC). The general information of patients, clinical catheterization effects and catheter-related complications were compared between the groups.

No significant differences in general information, catheter obstruction, catheter-related thrombosis, catheter exit-site bleeding and infection were found between the groups. The rate of successful insertion at the first attempt and patient satisfaction in the observation group were significantly higher than that in the control group (

 < 0.05). The time and cost of location and the incidence of catheter-related complications in the control group were 32.57 min and 140.51 Yuan and 21.5%, which were significantly higher than 6.94 min and 13.59 Yuan and 7.6% in the observation group (

 < 0.05).

IC-ECG accurately located the tip of femoral vein catheters, reduced the incidence of catheter-related complications and the time and cost of location, improved patient satisfaction.

IC-ECG accurately located the tip of femoral vein catheters, reduced the incidence of catheter-related complications and the time and cost of location, improved patient satisfaction.

To analyze auditory brainstem response (ABR) findings of preterm and term infants in the neonatal intensive care unit (NICU) with perinatal problems.

Case series with chart review.

Secondary care hospital.

Analysis consisted of a consecutive series of 101 infants (69 preterm and 32 term) admitted in the NICU of Hospital Fernando Fonseca between 2016 and 2018 with perinatal problems who underwent an ABR evaluation.

The major perinatal problems identified were hyperbilirubinemia, intravenous gentamicin >5 days, mechanical ventilation >5 days, congenital cytomegalovirus infection, meningitis, and periventricular hemorrhage. Gentamicin use significantly increased the absolute latency of wave I in preterm infants (95% CI, 0.01-0.37;

= .037). Mechanical ventilation significantly decreased the latency of wave V and intervals I-V and III-V in preterm infants (95% CI, -0.35 to -0.22;

= .026; 95% CI, -0.33 to -0.00;

= .001; 95% CI, -0.46 to 0.12;

= .049). Congenital cytomegalovirus significantly decreased interval III-V in preterm infants (95% CI, -0.36 to -0.01;

= .042).Multivariate analysis revealed that gentamicin use, lower gestational age, and lower birth weight predicted an increased ABR threshold in preterm infants (95% CI, 1.64-15.31;

= .016; 95% CI -1.72 to -0.09;

= .030; 95% CI, -14.55 to -0.63;

= .033). ABR measurements in term infants were not significantly altered, with the exception of an increased latency of wave III with a lower gestational age (95% CI, -0.49 to -0.01;

= .038).

These findings suggest that perinatal problems in the NICU significantly impair the ABR threshold and the auditory pathway maturational process in preterm but not term infants.

These findings suggest that perinatal problems in the NICU significantly impair the ABR threshold and the auditory pathway maturational process in preterm but not term infants.