Leslieschmidt9611

To explore regional brain glucose metabolic abnormalities of pretreatment stage I/II extranodal natural killer/T-cell lymphoma (ENKTL) patients using positron emission tomography with 2-deoxy-2-[fluorine-18]fluoro-D-glucose integrated with computed tomography (

F-FDG PET/CT) and assess its prognostic value.

Sixty pretreatment stage I/II ENKTL patients were enrolled in this retrospective study and divided into survival (n = 45) and death (n = 15) groups according to their status at the end of follow-up. A control group consisted of 60 healthy subjects. Regional cerebral glucose metabolism was evaluated on a voxel-by-voxel basis using statistical parametric mapping (SPM8) under a certain significance level (P < 0. 001) and voxel threshold (K = 100 voxels).

Decreased metabolism was noted in patients, involving the bilateral prefrontal and orbitofrontal cortex, partial parietal and occipital cortex, cingulate gyrus and cerebellum; the sensorimotor cortex was largely spared. Increased metabolism was obseatively poor prognosis but did not surpass the predictive values of ECOG and PINKE in stage I/II ENKTL patients.

Pretreatment stage I/II ENKTL patients exhibited abnormal regional cerebral glucose metabolism. Higher pretreatment glucose metabolism in BGT could predict a relatively poor prognosis but did not surpass the predictive values of ECOG and PINKE in stage I/II ENKTL patients.Obesity constitutes a major global health threat and is associated with a variety of diseases ranging from metabolic and cardiovascular disease, cancer to neurodegeneration. The hallmarks of neurodegeneration include oxidative stress, proteasome impairment, mitochondrial dysfunction and accumulation of abnormal protein aggregates as well as metabolic alterations. As an example, in post-mortem brain of patients with Alzheimer's disease (AD), several studies have reported reduction of insulin, insulin-like growth factor 1 and insulin receptor and an increase in tau protein and glycogen-synthase kinase-3β compared to healthy controls suggesting an impairment of metabolism in the AD patient's brain. Given these lines of evidence, in the present study we investigated brains of mice treated with 2 obesogenic diets, high-fat diet (HFD) and high-glycaemic diet (HGD), compared to mice fed with a standard diet (SD) employing a quantitative mass spectrometry-based approach. Moreover, post-translational modified proteinsith previous findings and aim to open new perspectives on the connection between diet-induced obesity and brain impairment.

Using social media (SM) for educational purposes might improve academic performance.

This paper aims to describe health science students' use of SM for educational purposes and its association with their academic performance.

Two hundred ninety-seven undergraduate health science students completed a self-administered questionnaire comprising 4 sections related to social media.

Almost all students (99.7%) reported using SM for learning, most (90.9%) of them daily. The most preferred type of SM learning was Facebook. Most students thought that using SM for learning is convenient and useful. They suggested there should be 1 Facebook account for each subject, that every classmate could access to obtain knowledge from lecturers and to interact between students and lecturers. The logistic regression model showed that the more time students practiced following the advice on posted information, the more likely they were to achieve a GPA at distinction level or above (OR = 4.2; OR = 5.4, and OR = 9.4, respectively with times of practicing). Taselisib Conversely, the students who used SM for learning less than once a month were less likely to obtain a GPA at distinction level (OR = 0.5).

Almost all health science students used SM to support learning and use of SM for learning was associated with higher academic performance.

Almost all health science students used SM to support learning and use of SM for learning was associated with higher academic performance.Chronic pain is a major clinical challenge in Scotland and across Europe as a whole. 18% of the UK population are currently affected by severe chronic pain. This has resulted in a significant impact on people's quality of life and affects their family, relationships and carers. This article discusses how a third sector organisation - Pain Association Scotland (PAS) - has completely changed their approach to service delivery after 33 years as a result of the COVID-19 pandemic as well as how they have worked with Health Boards in order to ensure a continued service which is equitable, trusted and provides continuity of service. The discussions are from the perspective of the Director, Sonia Cottom, BA (Hons) who has been with the Association for 10 years and who is ultimately responsible for the operations, strategic planning and service improvement and implementation. She is also advisor to the Scottish Government on chronic pain policy, providing the evidence to underpin future strategic decision making.Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) is a major public health, social, and economic problem in Ethiopia. Even though the government is working to scale up Anti-Retroviral Therapy (ART) services, patient loss to follow-up and ensuring adherence to ART regimens remain major challenges of the ART program in the country; little has also been done on the assessment of patient satisfaction on different HIV/AIDS service dimensions. This study aimed at assessing patient satisfaction with HIV/AIDS services in health centers of East Shoa Zone, Oromia region, Ethiopia. The study employed a cross-sectional survey between February and May 2017. Data was collected through exit interviews using five-point Likert scale-based questions and analyzed using Statistical Package for Social Sciences (SPSS) version 20. The overall mean patient satisfaction score was 3.16 (SD = 0.87) on a 1 to 5 scale. Availability of anti-Tuberculosis (anti TB) drugs in pharmacy was an item with the highest mean satisfaction score (4.18 ± 0.61) while waiting time to get pharmacy service was ranked least by the patients (mean score of 1.92, SD = 0.81). Merchants and students were more likely to be satisfied compared to other occupational groups. Overall, there was a wider gap in the study facilities concerning patient satisfaction and, therefore, health facility managers, Zonal and Woreda health offices, and Oromia Region Health Bureau should work in collaboration with other stakeholders to improve patient satisfaction with items for which the satisfaction score was low.