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The mean age of the included patient population was 56.5 (range, 24-81) years. The majority of them were hypertensive (n=26, 74.3%), and a quarter of them were on anticoagulant treatment (n= 9, 25%). The mean thrombin injection dose was 1000 U (range, 500-1500 U). In 34/35 (97.1%) patients, a thrombin injection resulted in complete thrombosis of the pseudoaneurysm lumen within a few seconds. There were no complications or recurrence of pseudoaneurysm after UGTI during the follow-up period. CONCLUSIONS Throughout the study period of 14 years, we did not encounter any procedural complications or arterial pseudoaneurysm recurrence. This is attributed to a safe procedural technique and proper patient selection. UGTI for arterial pseudoaneurysms is a safe, successful, and convenient treatment for both patients and surgeons.What kind of dynamic decision process do humans use to make decisions? In this article, two different types of processes are reviewed and compared Markov and quantum. Markov processes are based on the idea that at any given point in time a decision maker has a definite and specific level of support for available choice alternatives, and the dynamic decision process is represented by a single trajectory that traces out a path across time. When a response is requested, a person's decision or judgment is generated from the current location along the trajectory. By contrast, quantum processes are founded on the idea that a person's state can be represented by a superposition over different degrees of support for available choice options, and that the dynamics of this state form a wave moving across levels of support over time. When a response is requested, a decision or judgment is constructed out of the superposition by "actualizing" a specific degree or range of degrees of support to create a definite state. The purpose of this article is to introduce these two contrasting theories, review empirical studies comparing the two theories, and identify conditions that determine when each theory is more accurate and useful than the other. This article is categorized under Economics > Individual Decision-Making Psychology > Reasoning and Decision Making Psychology > Theory and Methods. © 2020 Wiley Periodicals, Inc.BACKGROUND Skeletal muscle mass (SMM) loss is common in metastatic colorectal cancer (mCRC) patients and associated with poor clinical outcomes, including increased treatment-related toxicities and reduced survival. Muscle loss may contribute to reduced health-related quality of life (HRQoL), including fatigue. Our aim was to study associations between changes in SMM and concomitant changes in patient-reported HRQoL. METHODS This was a secondary analysis of mCRC patients in the CAIRO3 randomized clinical trial who were-after initial treatment-randomized between maintenance treatment with capecitabine plus bevacizumab (CAP-B) and observation until first disease progression (PD1). Included patients had computed tomography images for SMM quantification, together with HRQoL assessments available at randomization and PD1. Changes in SMM (categorized as >2% loss, stable, and >2% gain) and HRQoL were computed between randomization and PD1. Changes in HRQoL score >10 points were considered clinically relevant. Associiations with SMM between the two treatment arms, we only found significant results in the observation arm. Here, associations were found for stable or gain in SMM with clinically relevant improved physical (12.4 for SMM gain), cognitive (10.7 and 9.7, respectively), and social functioning (15.5 and 15.6, respectively) as well as reduced appetite loss (-28.5 and -30.7, respectively). CONCLUSIONS In mCRC, SMM preservation during CAP-B and observation treatment is associated with significant and clinically relevant improvements in global health status and multiple functional and symptom scales. Studies are warranted to investigate whether interventions targeting SMM lead to improved HRQoL, fewer symptoms, and better functioning. © 2020 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders.It was our pleasure to read the article by Lone et al. (2019), who developed and assessed a three-dimensional (3D) application for dental anatomy education. The authors concluded that the application was of equivalent educational value with extracted teeth, while they stated that computer-based 3D models enhance teaching outcomes. Relevant literature was cited at the introduction of the article, in order to support the authors' point of view (Mitov et al., 2010; Wright and Hendricson, 2010). This article is protected by copyright. All rights reserved.INTRODUCTION Viral remission after analytical treatment interruption (ATI), termed post-treatment control, has been described in a small proportion of HIV-positive patients. This phenomenon has been separately associated to both low levels of HIV-1 proviral DNA as well as cell-associated RNA. selleck chemical We investigated whether the combination of both parameters could help predict delayed viral rebound after treatment interruption (TI). METHODS We conducted an open single-arm ATI study in four Belgian HIV reference centres from January 2016 to July 2018. Eligible participants were adults who had fewer than 50 HIV-1 RNA copies/mL for more than two years, more than 500 CD4 cells/µL for more than three months, and were in general good health. Consenting participants who had fewer than 66 copies total HIV-1 DNA (t-DNA) and fewer than 10 copies cell-associated HIV-1 unspliced RNA (US-RNA) per million peripheral blood mononuclear cells (PBMCs), interrupted therapy and were monitored closely. Antiretroviral therapy (ART) was reons Ltd on behalf of the International AIDS Society.BACKGROUND Eosinophilic chronic rhinosinusitis (eCRS) is an inflammatory endotype of CRS. Contemporary treatment includes creation of a "neo-sinus" cavity and postoperative corticosteroid irrigations. Not all patients gain control with local therapy. This study aims to determine, in patients with polyp recurrence, the most common sinuses involved. METHODS A prospective case-series was conducted on consecutive adult (≥18 years) post-FESS eCRS patients followed for a minimum of 12 months. All patients had a neo-sinus cavity created surgically and used corticosteroid irrigations daily for 3-6 months, then tapered to disease control. Sinus cavities were assessed by endoscopy on last follow-up. Polyp recurrence was defined as a score of 5 or 6 in the MLMES in ≥3 sinus cavities. Patient-reported outcomes based on SNOT22 and NSS, frequency of corticosteroid irrigations, and courses of systemic antibiotics and corticosteroid were collected. The pattern of sinus involvement was analyzed. RESULT A total of 342 sinus cavities were assessed (mean ± standard deviation, 54.