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In this study, a cellulose acetate (CA) membrane is formed as an interference rejection membrane on a glucose sensor to measure glucose in saliva. Glucose in saliva is successfully measured in vivo without any pretreatment of human saliva. A mouthguard (MG) glucose sensor is developed to monitor salivary glucose, which is reported to be correlated with the blood glucose level. Salivary components of ascorbic acid (AA) and uric acid (UA) hinder the accurate measurement of the glucose concentration of human saliva. CA-coated electrodes are prepared to investigate the interference rejection membrane. To measure hydrogen peroxide, which is a reaction product of glucose oxidase, effects of AA and UA are examined. Characteristics of the fabricated biosensor are examined on the basis of artificial saliva. The as-developed MG sensor can quantify the glucose concentration in the range of 1.75-10 000 μmol/L, which includes a salivary sugar concentration of 20-200 μmol/L. For the measurement of saliva samples collected from healthy subjects, the output corresponding to the concentration is confirmed; this suggests the possibility of glucose measurement. This MG glucose sensor can provide a useful method for the unrestricted and noninvasive monitoring of saliva glucose for the management of diabetes patients.The singlet fission (SF) channels in many systems are controlled by the thermodynamic driving force (Switch-1) and kinetic barrier (Switch-2), both of which could be modulated by chromophore structure dynamics and solvent properties. Using ab initio molecular dynamics (AIMD), we here simulate how the structural dynamics and solvent jointly govern singlet prefission energetics, taking a covalent BODIPY dimer (di-BODIPY) in solvents as an example. We report a general dual-switched dynamic channel for intramolecular SF in solvents and suggest an effective AIMD sampling method to characterize the joint effect of chromophore structure dynamics and the solvent impact on SFs. Results reveal that the joint effect not only provides di-BODIPY more chances for meeting the SF thermodynamic requirement (Switch-1 ON) but also tunes the charge-transfer state toward removing the kinetic barrier (Switch-2 ON). Two factors jointly govern each switch in the dual-switched SF channel, and any one does not open the channel alone. We suggest a general principle for dynamically dual-switching the SF channel in solvents by utilizing the joint effect to tune the pre-SF energetics for photoexcitation and the opening of the subsequent channel. AIMD sampling is used for the first time to discover explicit solvent-solute interaction and dynamics information and thus their effect on excitation energetics. This work also shows the statistical information for an ensemble of SF chromophores in solvents, which can undergo different photoexcitations and possible SFs. The high agreement of the findings here with the experiments justifies our AIMD sampling-based pre-SF energetic prediction as a reliable way for exploring novel SF systems and their controllability.Ionic liquid crystals have emerged as a new class of functional soft materials in the last two decades, and they exhibit synergistic characteristics of ionic liquids and liquid crystals such as macroscopic orientability, miscibility with various species, phase stability, nanostructural tunability, and polar nanochannel formation. Owing to these characteristics, the structures, properties, and functions of ionic liquid crystals have been a hot topic in materials chemistry, finding various applications including host frameworks for guest binding, separation membranes, ion-/proton-conducting membranes, reaction media, and optoelectronic materials. Although several excellent review articles of ionic liquid crystals have been published recently, they mainly focused on the fundamental aspects, structures, and specific properties of ionic liquid crystals, while these applications of ionic liquid crystals have not yet been discussed at one time. The aim of this feature article is to provide an overview of the applications of ionic liquid crystals in a comprehensive manner.The incorporation of manganese (Mn) ions into Cd(Zn)-chalcogenide QDs activates strong spin-exchange interactions between the magnetic ions and intrinsic QD excitons that have been exploited for color conversion, sunlight harvesting, electron photoemission, and advanced imaging and sensing. The ability to take full advantage of novel functionalities enabled by Mn dopants requires accurate control of doping levels over a wide range of Mn contents. This, however, still represents a considerable challenge. Specific problems include the difficulty in obtaining high Mn contents, considerable broadening of QD size dispersion during the doping procedure, and large batch-to-batch variations in the amount of incorporated Mn. Here, we show that these problems originate from the presence of unreacted cadmium (Cd) complexes whose abundance is linked to uncontrolled impurities participating in the QD synthesis. After identifying these impurities as secondary phosphines, we modify the synthesis by introducing controlled amounts of "functional" secondary phosphine species. This allows us to realize a regime of nearly ideal QD doping when incorporation of magnetic ions occurs solely via addition of Mn-Se units without uncontrolled deposition of Cd-Se species. Procyanidin C1 in vivo Using this method, we achieve very high per-dot Mn contents (>30% of all cations) and thereby realize exceptionally strong exciton-Mn exchange coupling with g-factors of ∼600.Since cell-based therapies require the constitutive and stable expression of therapeutic transgenes, lentiviral infection is commonly used to integrate gene material regulated by standard constitutive promoters. Unfortunately, none of the standard or synthetic constitutive promoters can be easily synthesized at low cost due to the presence of repeated subsequences. Thus, in this paper, we designed a synthetic constitutive promoter (named SFCp) that can drive the expression of fluorescent proteins that subsequently trafficked to intended subcellular localizations and the expression of synthetic proteins that rewired the cellular response of Ca2+ to cell morphology changes. Furthermore, SFCp can be used to avoid sequence homology that can theoretically result in loss of genetic material by homologous recombination in tandem constructs. As gene synthesis becomes an indispensable tool in the arsenal of synthetic biology, it is essential to develop a toolbox of gene synthesis friendly components for cell engineering such as constitutive promoters.