Haneycostello0133

At present, the breakthrough of the key techniques of artificial intelligence (AI), including image recognition, deep learning, neural network, Robot technique, etc., greatly promote the development of discipline crossing and medicine. In the present paper, we make an in-depth discussion about the future application of inter-discipline techniques of acupuncture-moxibustion and AI. We think that some of the current instruments have been part of the new acupuncture-moxibustion devices and may have the potential to intersect with the AI discipline. Relying on these existing devices and those of meridian detection, we can obtain relatively objective data, and further conduct meridian-syndrome differentiation and big data collection to possibly realize remote medical treatment. In addition, we may also develop an AI system for studying the underlying mechanisms of acupuncture and moxibustion therapies. Nevertheless, there still exist a lot of problems and challenges in clinical, teaching and scientific researches. It is recommended that the discipline of acupuncture-moxibustion should be intersected with the AI subject and formulate appropriate development strategies, promoting a faster and better development of acupuncturology.The meridian-collateral theory introduced in the classic book Huangdi Neijing (The Yellow Emperor's Canon of Internal Medicine,) has been being guiding the clinical diagnosis and treatment of diseases and health preservation by using traditional Chinese medicine (TCM) for thousands of years. However, despite of being the core theory of TCM, the meridian-colla-terals and their structural basis have not been scientifically clarified, which has become the "bottleneck" of the inheritance and innovation of TCM. It was reported in 2020 that the micro-channels formed by collagen fiber bundles in the skin and their contained components and the newly found interstitial cell, Telocyte, may be considered to be the ultra-micromorphological basis including their connection with the internal organs. In the present paper, we employed the Telocyte network and its relationships with other structures and cells to interpret, at the cellular level, various meridian hypotheses including 1) neurotheory, 2) humoral circulation theory, 3) biological field hypothesis, 4) fascia theory, 5) immune theory, 6) mast cell theory, 7) meridian-qi, and 8) elusive phenomenon of meridian. The absence of meridian-collaterals in morphology may be related to the difficulty of laboratory sample preparations of Telocyte processes in the continuity and completeness. We also proposed that the future research strategies should be aimed at revealing the morphological structure (including in vitro studies of the isolated and cultured Telocytes), establishment of relevant disease model, and clarification of the interrelation between the Telocyte network and the systems of nerve, blood circulation, immune, endocrine, and connective tissue.The theory of traditional Chinese medicine believes that meridian-collateral (jingluo) is an important system to maintain life and participates in the formation and cure of disease. Exploring the biological connotation of meridian-collateral is the key content in the modern research of traditional Chinese meridian. NCB-0846 chemical structure For more than 60 years, scholars at home and abroad have carried out the researches of meridian-collateral from the fields of biomedicine (e.g. physiology, anatomy and histomorphology), imaging, physics, chemistry, computer technology, etc. Meridian-collateral research in modern times demonstrates a multi-disciplinary historical development and provides multi-perspective scientific information for understanding meridian-collateral. The meridian-collateral research in future needs more accurate multidisciplinary intersection, which will be the light of hope to reveal the biological connotation of meridian-collateral.At present, acupuncture and moxibustion widely spread around the world, and its development is closely rela-ted to multidisciplinary integration. Interdisciplinary approaches are of great concern to the innovation and promotion of acupuncture-moxibustion therapy. Acupuncture and moxibustion, combined with optics, electrics, magnetics, infrared ray, microwave and other technologies, create the advanced and practical instrument for diagnosis and treatment of acupuncture and moxibustion and have made important contribution to clinical and teaching work. In the paper, focusing on the unique advantages of the science of acupuncture and moxibustion, the application of interdisciplinary approaches was explored to the promotion of acupuncture-moxibustion technology in its innovation and development, while the existing problems and countermeasures are further considered in the translational process of acupuncture-moxibustion technology to clinical application.Multidisciplinary intersection has gradually become a major source of scientific and technological innovation at present. But, how to leap over the discipline of acupuncture and moxibustion to promote the development of it is still a bottleneck problem. In the paper, based on the application of physical technology in acupuncture-moxibustion research, regarding the integration of traditional acupuncture and moxibustion with electrics, optics, acoustics and magnetics, the significance of it in theoretic study has been reviewed, as well as the current situation of its clinical application. It is anticipated to provide the ideas for the reform and development of acupuncture and moxibustion and the combination and innovation of acupuncture-moxibustion with other disciplines.Combining the current development of material science and acupunctology, we propose a new concept of "acupuncture-material science" as the new branch of acupunctology. We also hold that this new branch may be in the future the important direction of acupuncture-moxibustion instrument innovation. The future carding and development of the connotations and epita-xial contents of this discipline, the classification, applied range, research and development of the materials, as well as the related standard formulation, etc. should be paid more attention and improved in order to make greater contribution to the inheritance and innovation of acupunctology in the new era.