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n related complications.

The analysis determined the relapses in clubfoot children treated with Ponseti technique and standard bracing protocol and their correlation with overall follow up duration using pooled data from various series. It also tested the prescribed timelines of 5 and 7 years for slow-down/cessation of relapses in clubfoot children.

A systematic literature search was performed for articles published in "Pubmed (includes Medline indexed journals)" electronic databases using key words "Clubfoot or CTEV or congenital talipes equinovarus", "Ponseti" for years 1

January 2001 to 15

November 2020. Included were studies that addressed treatment of idiopathic clubfoot using the standard Ponseti technique, followed a well defined brace protocol (maintenance of corrected deformity using a central bar based brace and prescribed duration mentioned), reported a minimum mean follow up of 4 years and having relapse as one of their outcome measure. Studies reporting Ponseti technique for non-idiopathic clubfoot, child's age oor longer periods.

Depression has been implicated as a poor predictor of outcomes after total joint arthroplasty (TJA) of the lower extremity in some studies. We aimed to determine whether depression as a comorbidity affects the TJA outcomes and whether pain reduction associated with successful TJA alters depressive symptoms.

A search of PUBMED was performed using keywords "depression", "arthroplasty", "depressive disorder", and "outcomes." All English studies published over the last ten years were considered for inclusion. Quantitative and qualitative analysis was then performed on the data.

Thirty articles met inclusion criteria (16 retrospective, 14 prospective). Three showed that depressed patients were at higher risk for readmission. Lixisenatide ic50 Two reported that depressed patients had higher likelihood of non-home discharge after TJA compared to non-depressed patients. Four noted that depressed patients incur higher hospitalization costs than non-depressed patients. Ten suggest depression is a predictor of poor patient-reportedndergoing TJA.

The results of this review show that depression increases the risk of persistent pain, dissatisfaction, and complications after TJA. Additionally, depressed patients may incur higher costs than non-depressed patients undergoing TJA and may have worse preoperative and postoperative patient reported outcome measures (PROMs). However, the gains in function that depressed patients experience after TJA are equivalent to gains experienced by non-depressed patients and depressed patients may experience improvement in their depressive symptoms after TJA. Patient selection for TJA is critical and counseling regarding increased risk for complications is crucial in depressed patients undergoing TJA.[This corrects the article DOI 10.1016/j.jcot.2020.10.038.].With over 200 species of sharks reported from South African waters, the potential of discovering new blood parasites is very high. Unfortunately, this remains a poorly explored area of research, particularly in this biogeographical region. To date, only a single trypanosome species, Trypanosoma haploblephari Yeld and Smit, 2006, has been described from elasmobranchs off the coast of South Africa infecting the catsharks Haploblepharus pictus (Müller & Henle) and Haploblepharus edwardsii (Schinz). With only a single trypanosome species described and absence of molecular information, a study was conducted to provide further morphological and molecular information on T. haploblephari, a species considered not to demonstrate any pleomorphism. Thin blood smears were prepared, and blood was collected in molecular-grade ethanol from the caudal vein of two shark species, H. pictus and Poroderma pantherinum (Müller & Henle). Trypanosomes were morphologically described and molecularly characterised based on analysis of fragments of the 18S ribosomal gene. The presence of T. haploblephari in H. pictus was confirmed using the original description based on morphology, type host and locality, which allowed for the molecular characterisation of the species. In addition, this species was found parasitising P. pantherinum, its morphology considerably different in this host species as compared to that in the species of Haploblepharus, demonstrating that T. haploblephari may show extreme pleomorphism. This paper provides both morphological and molecular data for both morphotypes of T. haploblephari, with molecular comparisons to the only two other elasmobranch species of trypanosome for which sequence data is available. To elucidate the relationship of trypanosomes from aquatic hosts in general, more efforts need to be placed on elasmobranchs, as current phylogenetic studies are predominantly focused on trypanosomes infecting freshwater fishes.Reptile vector-borne diseases (RVBDs) of zoonotic concern are caused by bacteria, protozoa and viruses transmitted by arthropod vectors, which belong to the subclass Acarina (mites and ticks) and the order Diptera (mosquitoes, sand flies and tsetse flies). The phyletic age of reptiles since their origin in the late Carboniferous, has favored vectors and pathogens to co-evolve through millions of years, bridging to the present host-vector-pathogen interactions. The origin of vector-borne diseases is dated to the early cretaceous with Trypanosomatidae species in extinct sand flies, ancestral of modern protozoan hemoparasites of zoonotic concern (e.g., Leishmania and Trypanosoma) associated to reptiles. Bacterial RVBDs are represented by microorganisms also affecting mammals of the genera Aeromonas, Anaplasma, Borrelia, Coxiella, Ehrlichia and Rickettsia, most of them having reptilian clades. Finally, reptiles may play an important role as reservoirs of arborivuses, given the low host specificity of anthropophilic mosquitoes and sand flies. In this review, vector-borne pathogens of zoonotic concern from reptiles are discussed, as well as the interactions between reptiles, arthropod vectors and the zoonotic pathogens they may transmit.A systematic review was performed to assess the clinical outcomes of the reconstructive methods using autogenous grafts for the management of temporomandibular joint (TMJ) ankylosis A comprehensive electronic and manual search of the literature without date or language restriction was performed in January 2021 to identify randomized controlled trials, prospective, and retrospective studies with the aim of comparing the various surgical modalities for TMJ ankylosis. Twenty-six publications were included prospective (n = 17), retrospective (n = 7), randomised control trial (n = 1) and ambispective study (n = 1). Costochondral graft was the most common graft used followed by Coronoid process graft. Meta-analysis was not possible as most of studies were non-controlled in nature. Based on the available data, there was a strong evidence that autogenous grafts especially Costochondral grafts and coronoid grafts have remained one of the most favoured methods of reconstruction. Prospective and randomized control studies are recommended for the best stratification for the use of autogenous grafts for the management of TMJ ankylosis.