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To our knowledge, this is the first description of an OPDM treated with a combination systemic mineralocorticoid receptor antagonist and topical carbonic anhydrase inhibitor as adjuvant therapy to vitrectomy with favorable outcomes. We also review the literature and propose mechanisms through which these treatment entities may act.

The mechanisms underlying optic disc pit maculopathy remain controversial, and treatment guidelines are unclear. To our knowledge, this is the first description of an OPDM treated with a combination systemic mineralocorticoid receptor antagonist and topical carbonic anhydrase inhibitor as adjuvant therapy to vitrectomy with favorable outcomes. buy Combretastatin A4 We also review the literature and propose mechanisms through which these treatment entities may act.Reports of neuro-ophthalmological manifestations and complications in patients with coronavirus disease 19 (COVID-19) are still scarce. The aim of this article is to present optic neuritis, as possible post-infectious manifestation of COVID-19. Four weeks after hospitalization for seropositive coronavirus disease 19 (COVID-19), presented as bilateral bronchopneumonia, with radiology and laboratory findings also pointed to high clinical suspicion to COVID-19, a 63-year-old man developed a headache and subacute and profound visual loss on his right eye. The disease presentation was the right eye papillitis. Inflammatory parameters were normal at the time of hospitalization, and IgM and IgG for SARS-CoV-2 were still positive. After corticosteroid pulse therapy, his vision improved significantly and on follow-up visits returned to normal. All laboratory and radiology findings were unremarkable, except for antibodies against SARS-CoV-2 and myelin oligodendrocyte glycoprotein (MOG). We discuss about capacity of SARS-CoV-2 to cause optic neuritis and possible significance of MOG antibodies in similar cases.Auto-immune N-methyl-D-aspartate receptor encephalitis (NMDARE) is a relatively recently described cause of acute encephalopathy with very few reports from sub-Saharan Africa (SSA). We report a case of NMDARE in a young Kenyan female who was transferred to our facility with headaches, insomnia, behaviour changes and latterly pathognomonic orofacial dyskinesias. We comprehensively ruled out infectious and other inflammatory/auto-immune causes. She was diagnosed with NMDARE by positive antibody testing in serum and cerebrospinal fluid and changes on brain magnetic resonance imaging. She was immunosuppressed with high-dose steroids, intravenous immunoglobulins, plasma exchange and rituximab, and showed signs of neurological improvement clinically and radiologically. Unfortunately, she succumbed to septic shock from prolonged intensive care. This is the first report of NMDARE in an indigenous patient from the eastern SSA. The majority (>80%) of patients are either left with mild disability or make a full recovery after NMDARE, but some factors - which comprise the NMDARE One-Year Functional Status (NEOS) prognostication score - can adversely affect outcome, as was the case in our patient.

Every woman is entitled to respectful care during pregnancy and childbirth as a basic human right. However, not all women are being treated equally well.

This case study highlights some of the common disrespectful practices that women face. This is a testimony of a 28-year-old mother of two, narrated in her own words. The data were collected during an in-depth interview in November 2019. The interview was conducted in her house and her name has been changed to protect her identity. The interview was audio-taped using a digital voice recorder, later transcribed, and translated verbatim from the local language - Amharic, to English.

This woman's story highlights the unfortunate reality for some women. Five themes emerged from her narrative denial of care the provider left her unattended at a critical moment and denied her the care that she came for; non-consented care she did not consent to the episiotomy; non-dignified care she was carried by her arms and legs to the delivery couch, and left naked and bl to a facility where a relative works, as she no longer trusted these providers.

Abortion rates following unintended pregnancies are increasing in developing countries, and unsafe abortion is a commonly neglected reproductive health-care problem. In Ethiopia, the number of women receiving treatment for complications from unsafe abortion is increasing. Improving the level of knowledge of reproductive-age women on medication abortion contributes to the prevention of unsafe abortion. Therefore, the purpose of this study was to assess knowledge, and practice of medication abortion and associated factors among women in SRH clinics of Addis Ababa, Ethiopia, 2018.

A cross-sectional quantitative study design was conducted to collect data from 30th February to March 30, 2018. Study participants were selected by using a convenient sampling technique. The data were coded and entered into EpiData version 4.2, and SPSS version 23 was used for analysis. Bivariate and multivariate analysis with 95% CI were employed. The strength of association was declared at a P value <0.05.

The overall knowlereness creation and strengthened action to provide quality maternal care for childbearing mothers towards medication abortion and unsafe abortion in particular.

Among the many worldwide health problems, HIV/AIDS has caused severe health problems in several countries. The problem is also widely seen in Ethiopia. The general objective of the study is to cluster HIV patients and to find out the factors that mostly affect the prevalence of HIV within a group (cluster) and between groups (clusters) of HIV patients.

The study is made based on the 2016 Ethiopian Demographic Health Survey (EDHS) which was collected by the Central Statistical Agency (CSA) of Ethiopia, and the survey collected a total of 26,753 samples, of which 14,785 were women and 11,968 were men and the age group was between 15 and 49 years for both. Binary logistic regression, principal component analysis, cluster analysis, and ANOVA were applied to analyze the data.

The result from binary logistic regression reveals that 15 factors such as ever heard of AIDS, region, water not available for at least a day in the last 2 weeks, has a radio, family members wash their hands, location of the source of water, everything completed to water to make it harmless to drink, food cooked in the house/separate house/outside, has a mobile telephone, has a table, type of place of residence, highest education level attained, current marital status, sex of household members, and age of household members are all significant factors that affect HIV status.