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Over 70% of Americans regularly experience stress. Chronic stress results in cancer, cardiovascular disease, depression, and diabetes, and thus is deeply detrimental to physiological health and psychological wellbeing. Developing robust methods for the rapid and accurate detection of human stress is of paramount importance.

Prior research has shown that analyzing physiological signals is a reliable predictor of stress. Such signals are collected from sensors that are attached to the human body. Researchers have attempted to detect stress by using traditional machine learning methods to analyze physiological signals. Results, ranging between 50 and 90% accuracy, have been mixed. A limitation of traditional machine learning algorithms is the requirement for hand-crafted features. Accuracy decreases if features are misidentified. To address this deficiency, we developed two deep neural networks a 1-dimensional (1D) convolutional neural network and a multilayer perceptron neural network. Deep neural networks cy rates for binary and 3-class classification, respectively. The networks' performance exhibited a significant improvement over past methods that analyzed physiological signals for both binary stress detection and 3-class emotion classification.

We demonstrated the potential of deep neural networks for developing robust, continuous, and noninvasive methods for stress detection and emotion classification, with the end goal of improving the quality of life.

We demonstrated the potential of deep neural networks for developing robust, continuous, and noninvasive methods for stress detection and emotion classification, with the end goal of improving the quality of life.

Electrocardiogram (ECG) signal, an important indicator for heart problems, is commonly corrupted by a low-frequency baseline wander (BW) artifact, which may cause interpretation difficulty or inaccurate analysis. Unlike current state-of-the-art approach using band-pass filters, wavelet transforms can accurately capture both time and frequency information of a signal. However, extant literature is limited in applying wavelet transforms (WTs) for baseline wander removal. In this study, we aimed to evaluate 5 wavelet families with a total of 14 wavelets for removing ECG baseline wanders from a semi-synthetic dataset.

We created a semi-synthetic ECG dataset based on a public QT Database on Physionet repository with ECG data from 105 patients. The semi-synthetic ECG dataset comprised ECG excerpts from the QT database superimposed with artificial baseline wanders. We extracted one ECG excerpt from each of 105 patients, and the ECG excerpt comprised 14 s of randomly selected ECG data. Twelve baseline wanders weraccurately removed various baseline wanders. Daubechies-3 and Symlets-3 wavelets performed best. The study could facilitate future real-time processing of streaming ECG signals for clinical decision support systems.The 2020 International Conference on Intelligent Biology and Medicine (ICIBM 2020) provided a multidisciplinary forum for computational scientists and experimental biologists to share recent advances on all aspects of intelligent computing, informatics and data science in biology and medicine. ICIBM 2020 was held as a virtual conference on August 9-10, 2020, including four live sessions with forty-one oral presentations over video conferencing. In this special issue, ten high-quality manuscripts were selected after peer-review from seventy-five submissions to represent the medical informatics and decision making aspect of the conference. In this editorial, we briefly summarize these ten selected manuscripts.

Natural language processing (NLP) tools can facilitate the extraction of biomedical concepts from unstructured free texts, such as research articles or clinical notes. The NLP software tools CLAMP, cTAKES, and MetaMap are among the most widely used tools to extract biomedical concept entities. However, their performance in extracting disease-specific terminology from literature has not been compared extensively, especially for complex neuropsychiatric disorders with a diverse set of phenotypic and clinical manifestations.

We comparatively evaluated these NLP tools using autism spectrum disorder (ASD) as a case study. We collected 827 ASD-related terms based on previous literature as the benchmark list for performance evaluation. Then, we appliedCLAMP, cTAKES, and MetaMap on 544 full-text articles and 20,408 abstracts from PubMed to extractASD-related terms. We evaluated the predictive performance using precision, recall, and F1 score.

We found that CLAMP has the best performance in terms of F1 score followed by cTAKES and then MetaMap. GSK 2837808A Our results show that CLAMP has much higher precision than cTAKES and MetaMap, while cTAKES and MetaMap have higher recall than CLAMP.

The analysis protocols used in this study can be applied to other neuropsychiatric or neurodevelopmental disorders that lack well-defined terminology sets to describe their phenotypic presentations.

The analysis protocols used in this study can be applied to other neuropsychiatric or neurodevelopmental disorders that lack well-defined terminology sets to describe their phenotypic presentations.

When an Out-of-Hospital Cardiac Arrest (OHCA) incident is reported to emergency services, the 911 agent dispatches Emergency Medical Services to the location and activates responder network system (RNS), if the option is available. The RNS notifies all the registered users in the vicinity of the cardiac arrest patient by sending alerts to their mobile devices, which contains the location of the emergency. The main objective of this research is to find the best match between the user who could support the OHCA patient.

For performing matching among the user and the AEDs, we used Bipartite Matching and Integer Linear Programming. However, these approaches take a longer processing time; therefore, a new method Preprocessed Integer Linear Programming is proposed that solves the problem faster than the other two techniques.

The average processing time for the experimentation data was 1850 s using Bipartite matching, 32s using the Integer Linear Programming and 2s when using the Preprocessed Integer Linear Programming method.

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