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Several consumers lack a clear understanding of what makes a healthy diet. This uncertainty may be worsened by immigration due to socio-cultural differences. The purpose of this study was to explore Sub-Saharan African (SSA) pregnant women's perceptions of a healthy diet and the sources of dietary information available to them in the context of immigration. We used narrative interviews and photo-food diaries, followed by photo-elucidated interviews to obtain data. Participants defined and illustrated a healthy diet as having four characteristics (a) Familiar, (b) balanced, (c) made of fresh and organically grown ingredients, and (d) able to build the consumer's body. Participants indicated that the overwhelming nature of dietary information made it difficult to navigate. Participants trusted dietary recommendations offered by family and peers the most, while those offered by health care providers were reported to be difficult to understand or incorporate due to not being culturally specific. This paper highlights the importance of considering consumers' socio-cultural backgrounds and building partnerships between health care providers and the communities they serve to design culturally relevant dietary education.Introduction Liver diseases caused by hepatitis B virus (HBV) are pandemic infectious diseases that seriously endanger human health, conventional diagnosis methods can not meet the requirements in resource-limited areas. The point of acre detection methods can easily resolve those problems. Herein, we review the most recent advances in POC-based hepatitis B detection methods and present some recommendations for future development. It aims to provide ideas for future research. Areas covered Epidemiological data on Hepatitis B, conventional diagnostic methods for hepatitis B detection, some latest point of care detection methods for hepatitis B detection and list out the recommendations for future development. Expert opinion This manuscript summarized traditional biomarkers of different hepatitis B stages and recent-developed POCT platforms (including microfluidic platforms and lateral-flow strips) and discuss the challenges associated with their use. Some emerging biomarkers that can be used in hepatitis B diagnosis are also listed. This manuscript has certain guiding significance to the development of hepatitis B detection.This research is focussed to quantify IGF1 by electroanalytical analysis on InterDigitated electrode surface and characterized by the microscopic observations. For the detection, antibody and aptamer were used to analyze the level of IGF1. The sandwich pattern (aptamer-IGF1-antibody) was designed on the chemically modified IDE surface and reached the limit of detection to 10 fM with 100 folds enhancement in the sensitivity. Different control experiments (absence of IGF1, binding with IGF2 and with non-complementary aptamer) were failed to show the current changes, discriminated the specific detection. A good detection strategy is to complement the currently following imaging systems for AAA.Chronic disease prevention continues to be inadequate, overall and in achieving health equity, in spite of the many evidence-based practices and policies (EBPPs) available to address risk behaviors such as unhealthful eating, lack of physical activity, and tobacco use. Although clinical settings are needed for EBPPs that involve medical procedures such as immunization or early detection, dissemination of EBPPs can be effective in a variety of settings such as schools and childcare centers, worksites, social service organizations, and religious organizations. More implementation research is needed to meet challenges of effective application of EBPPs in such community settings, in which primary missions, capacity, cultures, and values do not focus on health services delivery. To address health equity, consideration of social and economic contexts of people reached in these settings is essential. This review presents lessons learned from past studies to guide future implementation research and practice across diverse settings and geographies.Advances in computing technology have spurred two extraordinary phenomena in science large-scale and high-throughput data collection coupled with the creation and implementation of complex statistical algorithms for data analysis. These two phenomena have brought about tremendous advances in scientific discovery but have raised two serious concerns. The complexity of modern data analyses raises questions about the reproducibility of the analyses, meaning the ability of independent analysts to recreate the results claimed by the original authors using the original data and analysis techniques. Reproducibility is typically thwarted by a lack of availability of the original data and computer code. A more general concern is the replicability of scientific findings, which concerns the frequency with which scientific claims are confirmed by completely independent investigations. Although reproducibility and replicability are related, they focus on different aspects of scientific progress. SNDX5613 In this review, we discuss the origins of reproducible research, characterize the current status of reproducibility in public health research, and connect reproducibility to current concerns about the replicability of scientific findings. Finally, we describe a path forward for improving both the reproducibility and replicability of public health research in the future.Introduction The increasing threat of antibiotic-resistant pathogens makes it imperative that new antibiotics to combat them are discovered. Burkholderia is a genus of Gram-negative, non-sporulating bacteria. While ubiquitous and capable of growing within plants and groundwater, they are primarily soil-dwelling organisms. These include the more virulent forms of Burkholderia such as Burkholderia mallei, Burkholderia pseudomallei, and the Burkholderia cepacia complex (Bcc).Areas covered This review provides a synopsis of current research on the natural products isolated from the genus Burkholderia. The authors also cover the research on the drug discovery efforts that have been performed on the natural products derived from Burkholderia.Expert opinion Though Burkholderia has a small number of pathogenic species, the majority of the genus is avirulent and almost all members of the genus are capable of producing useful antimicrobial products that could potentially lead to the development of novel therapeutics against infectious diseases.