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The data volume is exploding due to various newly-developing applications that call for stringent communication requirements towards 5th generation wireless systems. Fortunately, mobile edge computing makes it possible to relieve the heavy computation pressure of ground users and decrease the latency and energy consumption. What is more, the unmanned aerial vehicle has the advantages of agility and easy deployment, which gives the unmanned aerial vehicle enabled mobile edge computing system opportunities to fly towards areas with communication demand, such as hotspot areas. However, the limited endurance time of unmanned aerial vehicle affects the performance of mobile edge computing services, which results in the incomplete mobile edge computing services under the time limit. Consequently, this paper concerns the energy-efficient scheme design of the unmanned aerial vehicle while providing high-quality offloading services for ground users, particularly in the regions where the ground communication infrastructures are overloaded or damaged after natural disasters. Firstly, the model of energy-efficient design of the unmanned aerial vehicle is set up taking the constraints of the energy limitation of the unmanned aerial vehicle, the data causality, and the speed of the unmanned aerial vehicle into account. Subsequently, aiming at maximizing the energy efficiency of the unmanned aerial vehicle in the unmanned aerial vehicle enabled mobile edge computing system, the bits allocation in each time slot and the trajectory of the unmanned aerial vehicle are jointly optimized. T-DM1 datasheet Secondly, a successive convex approximation based alternating algorithm is brought forward to deal with the non-convex energy efficiency maximization problem. Finally, it is proved that the proposed energy efficient scheme design of the unmanned aerial vehicle is superior to other benchmark schemes by the simulation results. Besides, how the performance of proposed scheme design change under different parameters is discussed.We demonstrate a facile fabrication scheme for Co3O4@CoO@Co (gradient core@shell) nanoparticles on graphene and explore their electrocatalytic potentials for an oxygen evolution reaction (OER) and an oxygen reduction reaction (ORR) in alkaline electrolytes. The synthetic approach begins with the preparation of Co3O4 nanoparticles via a hydrothermal process, which is followed by a controlled hydrogen reduction treatment to render nanoparticles with radial constituents of Co3O4/CoO/Co (inside/outside). X-ray diffraction patterns confirm the formation of crystalline Co3O4 nanoparticles, and their gradual transformation to cubic CoO and fcc Co on the surface. Images from transmission electron microscope reveal a core@shell microstructure. These Co3O4@CoO@Co nanoparticles show impressive activities and durability for OER. For ORR electrocatalysis, the Co3O4@CoO@Co nanoparticles are subjected to a galvanic displacement reaction in which the surface Co atoms undergo oxidative dissolution for the reduction of Pt ions from the electrolyte to form Co3O4@Pt nanoparticles. With commercial Pt/C as a benchmark, we determine the ORR activities in sequence of Pt/C > Co3O4@Pt > Co3O4. Measurements from a rotation disk electrode at various rotation speeds indicate a 4-electron transfer path for Co3O4@Pt. In addition, the specific activity of Co3O4@Pt is more than two times greater than that of Pt/C.In the presented study, an overall Jaffa sweetie evaluation was made to find a correlation between Citrus grandis Osbeck × Citrus paradisi Macf. and its parent fruits' (Citrus grandis Osbeck, Citrus paradisi Macf.) properties. Based on the sensory analysis, it was found that the taste and aroma of the new hybrid fruit are close to pummelo. By the use of chromatographic analysis, the selected monoterpenes present in the fruits were quantified. α-terpineol was typed as the main monoterpene compound in the headspace of sweetie and grapefruit, with the concentrations 20.96 and 87.9 μg/g, respectively. In turn, γ-terpinene was chosen as the most important monoterpene determining the flavor of sweetie fruit. Based on two-dimensional gas chromatography (GC × GC-TOF-MS) and principal component analysis (PCA) of the data, several volatile compounds were associated with analyzed fruits' aroma. Jaffa Sweetie is the hybrid fruit with sensory properties similar to pummelo with a higher content of monoterpenes, which improves its health benefits compared to the parent fruit. The research presents an instrumental method for assessing the aroma properties of the fruit as a reference method for sensory analysis, commonly used in the industry.Melatonin (MLT) is a powerful chronobiotic hormone that controls a multitude of circadian rhythms at several levels and, in recent times, has garnered considerable attention both from academia and industry. In several studies, MLT has been discussed as a potent neuroprotectant, anti-apoptotic, anti-inflammatory, and antioxidative agent with no serious undesired side effects. These characteristics raise hopes that it could be used in humans for central nervous system (CNS)-related disorders. MLT is mainly secreted in the mammalian pineal gland during the dark phase, and it is associated with circadian rhythms. However, the production of MLT is not only restricted to the pineal gland; it also occurs in the retina, Harderian glands, gut, ovary, testes, bone marrow, and lens. Although most studies are limited to investigating the role of MLT in the CNS and related disorders, we explored a considerable amount of the existing literature. The objectives of this comprehensive review were to evaluate the impact of MLT on the CNS from the published literature, specifically to address the biological functions and potential mechanism of action of MLT in the CNS. We document the effectiveness of MLT in various animal models of brain injury and its curative effects in humans. Furthermore, this review discusses the synthesis, biology, function, and role of MLT in brain damage, and as a neuroprotective, antioxidative, anti-inflammatory, and anticancer agent through a collection of experimental evidence. Finally, it focuses on the effect of MLT on several neurological diseases, particularly CNS-related injuries.

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