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52; 95% CI 0.15-0.90), with low heterogeneity (I2=0.0%; p=0.648), while no significant increase (ES=0.67; 95% CI -0.70-2.04; I2=91.2%; p less then 0.001) was observed in patients with arterial disease. The only study in patients with peripheral arterial disease showed a significant increase in EPC levels. This meta-analysis indicates that exercise training may be a therapeutic option to improve EPC levels and potentially to enhance endothelial function and repair in patients with heart failure. L.U.This study presents a fast precision measurement method that uses pattern recognition. Abiraterone research buy First, a specific micro-structured surface was designed and manufactured, providing a unique pattern for recognition and matching. Second, a measurement system was proposed based on the algorithms of circle Hough transform (CHT), neural classifier (NC), template matching (TM) and sub-pixel interpolation (SI). Then, a series of experiments were carried out from three aspects circle detection, length uncertainty, and measurement speed and range. The results showed the correct circle classification percentage was more than 96% and the CHT search accuracy was within a two-pixel level. The length uncertainty test demonstrated the method was able to achieve 90-nm length uncertainty, and a comparison of measurement speeds showed it helped to speed up measurements by a factor of 1000 compared to the original one. Temperature in the cutting zone during dry machining has a significant effect on the tool life and surface integrity of the workpiece. This paper describes a comprehensive research on the cutting temperature in dry machining of ball screw under whirling milling by using infrared imaging. The effects of tool parameter and geometric parameter of workpiece together with the cutting parameters on the maximum and average temperatures in the cutting zone were analyzed in full detail. The influencing degree of these parameters on the maximum and average temperatures was affected by the value ranges of the parameters. In addition, the regression model and back propagation (BP) neural network model were proposed for predicting the maximum and average temperatures in the cutting zone. The verification of the predictive models showed that compared to the regression model, BP neural network model could predict the cutting temperature with high precision. The R2 of BP neural network model for predicting the maximum and average cutting temperatures in the cutting zone was higher than 99.8%, and the mean relative error and root mean square error were less than 4% and 19%, respectively. Separating the periodic transient impulses (PTIs) induced by localized failures from their observations and identifying the fault frequency with a high resolution is a primary challenge in bearing fault diagnosis. To address this issue, a novel time-frequency technique based upon sparse Daubechies-wavelet impulse isolation (SDWII) and horizontal-vertical synchrosqueezing transform (HV-SST) is proposed. The proposed approach consists of two basic processes (1) fault impulses isolation and (2) time-frequency feature extraction. First, the collected data on horizontal channel and vertical channel are respectively processed by the SDWII algorithm, wherein the Daubechies-wavelet and smooth nonconvex penalty are designed as the regularizers to enhance the sparsity of the estimated PTIs under the framework of sparse approximation. Conventional reassignment methods (e.g., synchrosqueezing transform, SST) localize both signal of interest and noise together by calculating the maximum values of the wavelet modulus (i.e., wavelet ridge) to sharpen the time-frequency representation, which yields a blurred y resolution. Inspired by the SST algorithm and the joint instantaneous frequency (JIF), we propose a HV-SST time-frequency reassignment method that attempts to identify the common fault characteristic of the obtained PTIs from the horizontal-vertical channels, with a single time-frequency diagram. Finally, the analysis results from a simulation case, an experimental case and an engineering case demonstrate that the proposed approach achieves a higher diagnostic accuracy and a higher time-frequency resolution compared with several state-of-the-art benchmarks. BACKGROUND The aim of this study was to compare the impact of different flight path models on the calculated population coverage of aeromedical retrieval systems, using the state of Alabama as a case study. METHODS Geospatial analysis of U.S. Census Bureau population data using helicopter bases and trauma centers as foci of either circular or elliptical coverage areas. RESULTS Circular isochrone models around helicopter bases or trauma centers suggest that the entire population of Alabama could reach a level I or II trauma center within 60 min. Elliptical isochrones, incorporating outbound and inbound flights, suggest that only 78.8% of the population have ready access to level I or II trauma centers. CONCLUSION While all three flight path models described have some validity and utility, simplistic circular flight time isochrones around trauma centers and helicopter bases provide overly optimistic estimates of population coverage. The elliptical model provides a more realistic evaluation. BACKGROUND Gallbladder cancer (GBC) has a poor prognosis. The aim was to develop and validate a preoperative risk score for incidental gallbladder cancer (IGBC) in patients scheduled for cholecystectomy. METHODS Data registered in the nationwide Swedish Registry for Gallstone Surgery (GallRiks) was analyzed, including the derivation cohort (n = 28915, 2007-2014) and the validation cohort (n = 7851, 2014-2016). An additive risk score model based on odds ratio was created. RESULTS The scoring model to predict IGBC includes age, female gender, previous cholecystitis, and either jaundice or acute cholecystitis. The calibration by HL test and discrimination by AUROC was 8.27 (P = 0.291) and 0.76 in the derivation cohort (214 IGBC) and 14.28 (P = 0.027) and 0.79 in the validation cohort (35 IGBC). The scoring system was applied to three risk-groups, based on the risk of having IGBC, eg. the high-risk group (>8 points) included 7878 patients, with 154 observed and 148 expected IGBC cases. CONCLUSION We present the first risk score model to predict IGBC.

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