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measured by the Catherine Bergego Scale and functional outcomes of right hemisphere stroke patients in inpatient rehabilitation settings.

Advanced.

The Association of Academic Physiatrists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.The Association of Academic Physiatrists designates this journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

The Association of Academic Physiatrists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.The Association of Academic Physiatrists designates this journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

To examine the effects of laser therapy on rheumatoid arthritis.

A search of controlled trials was conducted in different medical electronic databases. The primary outcome was immediate pain relief after treatment. Secondary outcomes were level of functional disability, morning stiffness duration, and 3-month follow-up for pain.

Ten trials met the inclusion criteria. Rheumatoid arthritis treatment with laser therapy significantly improved immediate pain relief [standardized mean difference (SMD), -0.839; 95% confidence interval (CI), -1.336, -0.343] and overall functional score (SMD, -0.309; 95% CI, -0.587, -0.031). There was no significant improvement in morning stiffness duration (SMD, -0.519; 95% CI, -1.176, 0.138) and 3-month follow-up for pain (SMD, -1.125; 95% CI, -2.311, 0.061). There was no publication bias (Egger's regression, p=0.277). However, heterogeneity was noted despite the removal of an outlier (Q=18.646; I2=57.096). Results of subgroup analyses suggested that high-intensity laser therapy and nerve irradiation is better suited for immediate pain relief. Meta-regression analyses showed no significant linear relationship between the treatment effect with laser wavelength or number of treatment sessions.

Laser therapies provide significant immediate pain relief and improve function for rheumatoid arthritis patients, but without significant improvement in morning stiffness duration and 3-month follow-up for pain.Systematic review registration number CRD42020192906.

Laser therapies provide significant immediate pain relief and improve function for rheumatoid arthritis patients, but without significant improvement in morning stiffness duration and 3-month follow-up for pain.Systematic review registration number CRD42020192906.

To examine peri-operative medication patterns, surrounding major amputation surgeries.

Retrospective chart review of 216 cases of major amputations (transfemoral, hip disarticulation, hemipelvectomy, forequarter) at an academic hospital, examining medications, dosing changes and drug-drug interaction warnings pre- and post-operatively.

Medications increased in 76.9% (166/216), remained the same in 10.6% (23/216), and decreased in 12.5% (27/216) of cases. Average number of medications was 7 pre-operatively and 10 post-operatively. In 189 cases with pre-operative medications present, post-operative dosing remained the same for 74.3%, increased for 9.2%, decreased for 7.6% and was unknown for 8.9% of medications. Increases in each of type C ("monitor therapy"), D ("consider therapy modification) and X ("avoid combination") drug-drug interaction warnings were seen respectively in 59.7%, 62.0% and 5.1% of cases.

Polypharmacy is involved pre-operatively and increased post-operatively in most cases of major limb amputation, with agent dosing remaining the same or increased in the majority of cases. Drug-drug interaction warnings also increase. These occur at a time of abrupt changes to the body's size, compartments, and physiologic responses. More research and clinical attention are warranted given anticipated changes in pharmacokinetics and pharmacodynamics.

Polypharmacy is involved pre-operatively and increased post-operatively in most cases of major limb amputation, with agent dosing remaining the same or increased in the majority of cases. Drug-drug interaction warnings also increase. These occur at a time of abrupt changes to the body's size, compartments, and physiologic responses. More research and clinical attention are warranted given anticipated changes in pharmacokinetics and pharmacodynamics.

The U.S. primary care workforce remains inadequate to meet the health needs of the U.S. population. selleck Effective programs are needed to provide workforce development for rural and other underserved areas.

At the University of North Carolina (UNC) School of Medicine (SOM), between November 2014 and July 2015, the authors developed and implemented the Fully Integrated Readiness for Service Training (FIRST) Program, an accelerated curriculum focused on rural and underserved care that links 3 years of medical school with a conditional acceptance into UNC's 3-year family medicine residency, followed by 3 years of practice support post-graduation. Students are recruited to the FIRST Program during the fall of their first year of medical school. The FIRST Program promotes close faculty mentorship and familiarity with the health care system, includes a longitudinal quality improvement project with an assigned patient panel, includes early integration into the clinic, and fosters a close cohort of fellow students.

As of March 2020, the FIRST Program had successfully recruited 5 classes of medical students and 3 of those classes had matched into residency. In total, as of March 2020, 18 students had participated in the FIRST Program.

The FIRST Program will be expanded to additional clinical sites across North Carolina and to specialties beyond family medicine, including pediatrics, general surgery, and psychiatry.

The FIRST Program will be expanded to additional clinical sites across North Carolina and to specialties beyond family medicine, including pediatrics, general surgery, and psychiatry.

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