Mathiassenellington3567

In Study 3 (n = 235 community women), the PBSS-R explained variance in intuitive eating and happiness above theoretically related measures of self-objectification and body shame, supporting the scale's incremental validity. We recommend use of this abbreviated measure to assess the more embodied and less evaluative features of body shame in women.

The properties of the oxidized surface for common materials, such as silicon and titanium, are known to be markedly different from the reduced surface. We hypothesize that surface-oxidized aluminum gallium nitride ((oxidized-AlGaN)/GaN) surface charge behavior is different to unoxidized AlGaN (with ultrathin native oxide only), which can be validated via surfactant adsorption. Understanding these differences will explain why (oxidized-AlGaN)/GaN-based sensors are better performing than AlGaN ones, which has been previously demonstrated but not understood.

The surface of an AlGaN/GaN structure was oxidized with hot piranha solution and oxygen plasma. AFM force measurements and imaging were performed to probe the charge properties of the surface in aqueous solutions of varying pH containing only an acid or base, or with an added ionic surfactant cationic cetyltrimethylammonium bromide (CTAB) or anionic sodium dodecylsulfate (SDS).

The (oxidized-AlGaN)/GaN surface is positively charged at pH 4 and pH 5.5, ositively charged. Compared to unoxidized AlGaN, the (oxidized-AlGaN)/GaN surface shows a wider range of surface charge magnitude over pH values between 2 and 12. This suggests that the (oxidized-AlGaN)/GaN surface has a higher surface hydroxyl group density than unoxidized AlGaN, which explains the higher sensitivity for pH sensors based on (oxidized-AlGaN)/GaN structures.Photodegradation has attracted much attention in wastewater treatment owing to its nontoxicity, high efficiency, and mild reaction conditions. Recently, Zr/Ag co-doped titanium dioxide (TiO2) nanoparticles have been synthesized and showed high photocatalytic activity for dye, but these nanoparticles tend to aggregate together, leading to reduced catalytic sites, which is disadvantageous for their practical application. Therefore, Zr/Ag-co-doped TiO2 nanofibers were prepared using an electrospinning method. For comparison, TiO2 nanofibers and Zr-doped TiO2 nanofibers were also fabricated. The synthesized catalysts were characterized by X-ray diffraction, UV-visible absorption spectroscopy, diffuse reflectance spectroscopy, scanning electron microscopy, attenuated total reflectance Fourier transform infrared spectroscopy, zeta potentials, photoluminescence, and electrochemical impedance spectroscopy. Compared with TiO2 nanofibers and Zr-doped TiO2, Zr/Ag co-doped TiO2 nanofibers have significantly enhanced photocatalytic activity for Congo red owing to the synergetic effects of Zr, Ag, and Ti. The photodegradation of Congo red followed a pseudo-first-order kinetic model. The optimal Zr/Ag-co-doped TiO2 nanofibers with 2 wt% Ag and a mass ratio of ZrO2 to TiO2 of 19 exhibits the best photocatalytic activity and the corresponding kinetic constant of 0.0405 min-1 is 12 times higher than that of TiO2 nanofibers. This work will provide data and a technology base for the synthesis of future materials with high photocatalytic activity.

Banxia Xiexin decoction (BXD), a traditionally prescribed Chinese medicine, has been used to treat chronic gastritis for many years. However, the underlying mechanism and targets for its effects remain unknown. In the present study, we predicted the targets and active compounds of BXD in the treatment of chronic gastritis through network pharmacology and ultra-performance liquid chromatography coupled with linear trap quadrupole-Orbitrap mass spectrometry (UPLC-LTQ-Orbitrap MS).

A chronic gastritis model was established in rats by oral administration of 56 % ethanol. BXD was orally administered for 7 days. Stomach tissues were collected for histopathological analysis, and tumour necrosis factor (TNF)-α, interleukin (IL)-2, IL-8, and lactate dehydrogenase (LDH) levels were measured by enzyme-linked immunosorbent assay. UPLC-LTQ-Orbitrap MS was established to analyse compounds in rat plasma following oral BXD administration. The absorbed ingredients were selected as candidate active compounds. The chronic ggy of network pharmacology combined with SPR may provide a feasible approach to explore the targets of herbal medicine and uncover novel bioactive components.In light of recent advances in RNA splicing modulation as therapy for specific genetic diseases, there is great optimism that this approach can be applied to treatment of cancer as well. Dysregulation of alternative RNA splicing is a common aberration detected in many cancers and thus, provides an attractive target for therapeutics. Here, we present and compare two promising approaches that are currently being investigated to manipulate alternative splicing and their potential use in therapy. The first strategy makes use of splice-switching oligonucleotides, whereas the second strategy uses CRISPR (clustered regularly interspaced short palindromic repeat Cas (CRISPR-associated) technology. We will discuss both the challenges and limitations of these technologies and progress being made to implement splice-switching as a potential cancer therapy.

The aim of this study was to explore the association of vitamin D (VitD) levels during pregnancy and its metabolic pathway genes with the risk for preterm birth (PTB) among pregnant women in southeast China.

This study was conducted in Zhoushan Maternal and Child Health Hospital, Zhejiang, from August 2011 to May 2018. Plasma 25-hydroxyvitamin vitamin D [25(OH)D] levels in three trimesters and single-nucleotide morphisms in the VitD metabolic pathway were measured. Relevant information was collected using questionnaires and an electronic medical recorder system. Multiple statistical methods including linear regression, logistic regression, and crossover analysis were applied.

The prospective cohort study included 3465 pregnant women, of which 202 were PTB (week of gestation at delivery 33.38 ± 4.05), accounting for 5.8%. Lartesertib ic50 After adjusting for potential confounders, VitD sufficiency (≥30 ng/mL) in the second and third trimesters was associated with longer gestational age at delivery compared with VitD deficiency (<20 ng/mL).