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c) 2021 APA, all rights reserved).Objective Abnormal white matter (AWM) on magnetic resonance imaging is associated with cognitive performance in older adults. selleck inhibitor We explored cognitive associations with AWM during late-midlife. Method Participants were community-dwelling men (n = 242; M = 61.90 years; range = 56-66). Linear-mixed effects regression models examined associations of total, periventricular, and deep AWM with cognitive performance, controlling for multiple comparisons. Models considering specific cognitive domains controlled for current general cognitive ability (GCA). We hypothesized that total AWM would be associated with worse processing speed, executive function, and current GCA; deep AWM would correlate with GCA and periventricular AWM would relate to specific cognitive abilities. We also assessed the potential influence of cognitive reserve by examining a moderation effect of early life (mean age of 20) cognition. Results Greater total and deep AWM were associated with poorer current GCA. Periventricular AWM was associated with worse executive function, working memory, and episodic memory. When periventricular and deep AWM were modeled simultaneously, both retained their respective significant associations with cognitive performance. Cognitive reserve did not moderate associations. Conclusions Our findings suggest that AWM contributes to poorer cognitive function in late-midlife. Examining only total AWM may obscure the potential differential impact of regional AWM. Separating total AWM into subtypes while controlling for current GCA revealed a dissociation in relationships with cognitive performance; deep AWM was associated with nonspecific cognitive ability whereas periventricular AWM was associated with specific frontal-related abilities and memory. Management of vascular or other risk factors that may increase the risk of AWM should begin during or before early late-midlife. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Over the last couple of years, the topic of White fragility has garnered a considerable degree of attention. White fragility is considered a state in which even a minimum amount of racial stress can become intolerable and trigger a range of emotional and behavioral reactions intended to restore a sense of racial comfort (DiAngelo, White fragility Why it's so hard for White people to talk about racism, 2018, Beacon Press). In effort to measure the expression of White fragility, we developed and evaluated the psychometric properties of the 21-item White Fragility Scale (WFS). Data consisted of two independent samples of White participants recruited from M-Turk (327) and a Midwest University's Psychpool (234). Results from exploratory and confirmatory factor analyses provided evidence for a bifactor model consisting of one general White fragility factor and three specific factors of Emotional Defensiveness, Accommodation of Safety, and Exceptionism. Ancillary bifactor indices supported treating the WFS as a unidimensional measure of White fragility yet also revealed meaningful utility of the Accommodation of Safety subscale. Concurrent validity evidence for the WFS was established through significant associations with modern racism, general and specific dimensions of colorblind racial attitudes, and social dominance orientation. In addition, nonsignificant, near-zero correlations with social desirability provided support for divergent validity. Recommendations for future research involving the WFS are provided as well as practical implications for professionals whose work requires a certain degree of racial stamina. (PsycInfo Database Record (c) 2021 APA, all rights reserved).This study aimed to investigate change in insight into maladaptive interpersonal patterns over the course of psychotherapy, as well as the specificity of insight as a change mechanism in dynamic treatments. A total of 100 patients received up to 16 sessions of either cognitive or dynamic therapy for major depressive disorder in a randomized clinical trial. Assessments of insight (Insight into Conflictual Relationship Patterns scale) and depression severity (Hamilton Depression Inventory) took place at the beginning of treatment, at month 2, and month 5. Patient insight significantly improved over the course of dynamic treatments. Gains in insight from the beginning to month 2 of treatment were a significant predictor of decreases of depressive symptoms from month 2 to month 5 of treatment in the dynamic, but not in the cognitive treatment group, despite a nonsignificant interaction. Results provide support for insight as a change factor in dynamic therapies. Better self-understanding of dysfunctional interaction patterns could help patients to find more adaptive ways of behaving, to form more satisfying relationships, and to improve their depression. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Recent theories of suicide behavior have proposed a risk factor that differentiates suicide ideators from suicide attempters Suicide capability. Fearlessness about death, one component of capability, has predicted the likelihood of a future attempt in adult samples. Although there is preliminary evidence about its value in youth, the fearlessness about death scale (FAD) has not yet been validated in clinical adolescents. We sought to examine the psychometric properties of this scale in adolescents at high risk for making a future suicide attempt. Youth who were evaluated for an intensive outpatient program (IOP) for suicidal adolescents (N = 496; M, SD for age = 14.78, 1.59) reported lifetime history of suicide attempts and NSSI, suicide ideation, depressive symptoms, and completed the FAD at entry and at discharge (n = 329). Confirmatory factor analysis showed structural validity of the FAD scale and its invariance across age, sex, and time. Independent t-tests indicated that FAD scores distinguished between those with and without NSSI, as well as those with single versus multiple attempts. When depression was covaried in logistic regression analyses, FAD's relationship with suicide attempt history persisted, showing the construct's divergence from depression. Our findings present psychometric validity in adolescents for a widely used scale developed for adults. This validation offers confidence that this promising risk factor can be adequately investigated in adolescents. If future studies can confirm its predictive validity, the brevity of this scale would make it a practical addition to a clinical assessment. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

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