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Fifty-gray single dose was used in all cases. Two had pasteurization and reimplantation. Thirty seven had non-reimplantation reconstructions (including intercalary or osteoarticular endoprosthesis, pedicled bone grafts, rotation-plasty, and amputations). Five-year local recurrence-free survival was 85% for reimplantation and 97% for non-reimplantation groups (p=0.17). Five-year metastasis-free survival was 63% and 54%, respectively (p=0.44). Five-year overall survival was 70% and 58%, respectively (p=0.39). The data from this study did not demonstrate significantly better local recurrence-free, distant relapse-free, or overall survival benefit in the tumor bone reimplantation group. Copyright © 2020 Prakash Nayak et al.Dam operations are known to have significant impacts on reservoir hydrodynamics and solute transport processes. The Gardiner Dam, one of the structures that forms the Lake Diefenbaker reservoir located in the Canadian Prairies, is managed for hydropower generation and agricultural irrigation and is known to have widely altering temperature regimes and nutrient circulations. This study applies the hydrodynamic and nutrient CE-QUAL-W2 model to explore how various withdrawal depths (5, 15, 25, 35, 45, and 55 m) influence the concentrations and distribution of nutrients, temperature, and dissolved oxygen (DO) within the Lake Diefenbaker reservoir. As expected, the highest dissolved nutrient (phosphate, P O 4 3 - - P and nitrate, N O 3 - - N ) concentrations were associated with hypoxic depth horizons in both studied years. During summer high flow period spillway operations impact the distribution of nutrients, water temperatures, and DO as increased epilimnion flow velocities route the incoming water through the surface of the reservoir and reduce mixing and surface warming. This reduces reservoir concentrations but can lead to increased outflow nitrogen (N) and phosphorus (P) concentrations. Lower withdrawal elevations pull warmer surface water deeper within the reservoir and decrease reservoir DO during summer stratification. During fall turnover low outflow elevations increase water column mixing and draws warmer water deeper, leading to slightly higher temperatures and nutrient concentrations than shallow withdrawal elevations. The 15 m depth (540 m above sea level) outflow generally provided the best compromise for overall reservoir and outflow nutrient reduction. © Meghan K. Carr et al. 2020; Published by Mary Ann Liebert, Inc.Despite the importance of identifying individuals with reading disabilities, existing operational definitions of reading disability do not result in reliable identification. A large part of the problem arises from measurement error when a cut-point is imposed on a continuous distribution, especially for low base-rate conditions. One way to reduce measurement error is to include additional predictors in reading disability models. selleck chemicals llc The present study examined co-occurring math disability as a possible additional criterion for predicting reading disability. Meta-analysis was used to examine the probability of individuals with reading disability also having a comorbid math disability. Possible moderators including age, severity of disability, and language were examined. The main result was an average weighted odds ratio of 2.12, 95% confidence interval [1.76, 2.55], indicating that students with a math disability are just over two times more likely to also have a reading disability than those without a math disability. Implications of the results are discussed.In embedded biomedical applications, spectrum analysis algorithms such as Fast Fourier Transform (FFT) are crucial for pattern detection and has been the focus of continued research. In deeply embedded systems such as cardiac pacemakers, FFT based signal processing is typically computed by Application Specific Integrated Circuits (ASIC) to achieve low power operation. This research proposes a data driven design approach for an FFT ASIC solution which exploits the limited range of data encountered by these embedded systems. The optimizations proposed in this paper uses the simple concept of Hashing and Look-Up Tables (LUT) to effectively reduce the number of arithmetic operations required to perform the FFT of an electrocardiogram (ECG) signal. By reducing the dynamic power consumption and overall energy footprint of FFT computation, the proposed design aims to achieve longer battery life for a Cardiac Pacemaker. The design is synthesized using a 90nm standard cell library, and gate level switching activity is simulated to obtain accurate power consumption results. The proposed optimizations achieved a low energy consumption of 27.72nJ per FFT, which is 14.22% lower than a standard 128-point radix-2 FFT when tested with actual ECG data collected from PhysioNet.Introduction The purpose of this study is to investigate the relationship between preoperative hyponatremia and postoperative complications in aseptic revision hip and knee arthroplasty. Methods Aseptic revision arthroplasties from 2007 to 2016 were collected using a large, United States database. Patients were stratified into eunatremic and hyponatremic cohorts. Rates of complications were collected and analyzed. Results 25,517 surgeries were evaluated. Preoperative hyponatremia was independently associated with organ/space infections (OR= 2.316; p less then 0.001), postoperative blood transfusions (OR= 1.467; p less then 0.001), pneumonia (OR= 2.05; p =0.002), sepsis (OR= 2.533; p less then 0.001), extended length-of-stay (OR= 2.221; p less then 0.001), minor complications (OR= 1.549; p less then 0.001), wound complications (OR= 1.505; p=0.001), pulmonary complications (OR= 1.72; p=0.007), and sepsis complications (OR= 2.305; p less then 0.001). Conclusion Hyponatremia is an independent risk factor for several postoperative complications in aseptic revision hip and knee arthroplasty. © 2020 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.Objective Assessing financial effects of removal of TKA from CMS inpatient-only list on physician-owned bundles. Methods We determined whether Medicare TKAs remained inpatient, versus changed to observational. We used CMS data to determine savings. Direct costs associated with BPCI were calculated. Results 7/28 TKAs (25.0%) had inpatient status changed to observational, excluding them from BPCI. Estimated savings losses were $24,332. Direct costs for administrating BPCI were $51,250. Had the rate of patients changed to observational been 50%, bundle savings from remaining patients would be less than direct costs. Conclusion Removing TKA from CMS inpatient-only list may have negative financial implications. © 2020 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.

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