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Jelgersma's theories are discussed against the background of more recent theories of cerebellar function that, similarly, are based on the double innervation of the Purkinje cells. The amoeboid hypothesis is traced to its roots in the late nineteenth century.Phytoestrogens are naturally plant-derived compounds that could bind to estrogen receptors and mimic estrogenic effects. Previous studies showed a positive association between phytoestrogens and hypothyroidism; however, little is known on phytoestrogens and thyroid hormones. This study was designed to investigate the associations between urinary phytoestrogens and thyroid hormone levels. Based on the US National Health and Nutrition Examination Survey (NHANES) 2007-2010, 4103 participants were recruited in this cross-sectional study. Linear regression models and multiple linear regressions models were applied to examine the relationships between urinary phytoestrogens and thyroid hormone levels. Urinary O-desmethylangolensin (O-DMA) was found to be correlated with serum FT4 levels in the female 20-60-year-of-age group (β=0.018, 95% CI 0.006, 0.031). Higher enterolactone (ENT) levels were significantly positively associated with TSH levels in the 12-19-year-of-age female group (β=0.196, 95% CI 0.081, 0.311). In the male group, enterodiol (END) was significantly positively correlated with TSH and TT3 in the 12-19-year-of-age group, respectively (TT3 β=3.444, 95% CI 0.150, 6.737; TSH β=0.104, 95% CI 0.005, 0.203). However, equol (EQU) levels were negatively associated with TT4 (12-19-year-of-age β=- 0.166, 95% CI - 0.279, - 0.034; 20-60-year-of-age β=- 0.132, 95% CI - 0.230, - 0.034). Our study provided epidemiological evidence that urinary phytoestrogens were powerfully associated with thyroid hormone levels. The results also supported that phytoestrogens acted as endocrine disruptors. It is imperative and important to pay attention to the intake of phytoestrogens.Biosorption is a simple and economical method utilized to remove hazardous elements from a waste solution. In this study, a low-cost agricultural waste, Salvadora Persica, was modified with iron oxyhydroxide and evaluated as an economic biosorbent to remove cesium and europium radionuclides from their aqueous solutions. BSJ-4-116 The modified biosorbent was characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), X-ray diffraction (XRD), elemental analysis as well as thermogravmetirc analysis (TGA). The sorption of 134Cs and 152+154Eu radioisotopes was investigated singly in a batch mode as a function of the solution pH, contact time, and the initial concentrations of the studied ions. link2 The kinetic of the removal process was examined and it was found that the reaction obeys a pseudo-first-order model and the intraparticle diffusion is not the sole mechanism dominating the reaction. Temkin and Sips isotherm models provide the best fit for the equilibrium data. In addition, the sorption of cesium and europium ions was a spontaneous and endothermic process as inferred from thermodynamic studies. The reusability for the sorption of cesium and europium ions reveals the feasibility and efficacy of the modified biosorbent.The total factor CO2 emission performance (TFCEP) of transportation industry has received increasing research interests, while existing literature pays little attention to its regional inequality and driving factors. In order to uncover the regional inequality of TFCEP in China's transportation industry, this paper used Theil index and combined with geographical detector model (GDM) to explore the driving factors and their interactions on TFCEP in Chinese transportation industry. The results revealed that the TFCEP of transportation industry showed a promising increase during 2003-2017 with an annual growth rate of 0.12%, and the improvement was contributed by the technical efficiency change. The TFCEP in the Eastern region performed better than that in the Northeast, Central, and Western region. Regional inequality of TFCEP did exist and exhibited an obvious downward trend. The within-region inequality had a greater impact on the inequalities than between region. Freight turnover was the main driving factor of TFCEP in the transportation industry, followed by the energy intensity and per-capita GDP. In the Eastern and Western regions, freight turnover had the greatest impact on TFCEP, while in the Central and Northeastern regions, urbanization rate and energy intensity were the dominant factors, respectively. link3 The interactions between energy intensity and freight turnover were highly influential. This paper provides important insights for different regions to formulate targeted carbon emission reduction policies.Two novel absorbents were synthesized for the first time by banana and pomegranate peels using diethylenetriaminepentaacetic acid (DTPA) modification to eliminate Cd(II) and Ni(II) of sewage. The DTPA-modified peels performed significantly higher adsorption capacity than unmodified materials. The maximum adsorption capacities of DTPA-modified banana/pomegranate peel were 46.729/46.296 mg/g for Cd(II), and 29.240/16.611 mg/g for Ni(II). Adsorption isotherm and kinetics models were simulated to determine their removal efficiency and potential for recovery of these two heavy metals. As the results, the adsorption reached equilibrium within 5 min and was well described by the pseudo-second order model and Langmuir isotherm. The surface morphology analysis of the synthetic materials by Scanning Electron Microscopy-Energy Dispersive X-ray spectroscopy, Fourier Transform Infrared spectroscopy, and X-ray Photoelectron Spectroscopy, implied that ion exchange, complexation, and physical adsorption may together contribute to Cd(II) and Ni(II) loading on DTPA-modified peels. This study demonstrates the feasibility of waste peels as cost-efficient bio-absorbents to remove Cd(II) and Ni(II) in sewage systems, and discovers potential adsorption mechanism of efficiency improvements after DTPA modification.COVID-19 pandemic waves hitting worldwide result in drastic postinfection complications with interindividual variations, which raised the question for the cause of these observed variations. This urged to think "the impact of environment-affected genes"? In an attempt to unravel the impact of environment-affected genes, a systematic rapid review was conducted to study "the impact of host or viral epigenetic modulation on COVID-19 infection susceptibility and/or outcome." Electronic databases including Web of Science, SCOPUS, Cochrane Central Register of Controlled Trials, PubMed, and Google Scholar, and other databases were searched. The search strings included "COVID-19" OR "SARS-CoV-2" AND (Epigenetics'). Articles with randomized clinical trials (RCTs) and observational study designs, conducted on humans and available in the English language, were selected, with respect to "The interplay between the SARS-CoV-2 virus and Epigenetics" published from 2020 to February 2021 (but not limited to 2020, being expanded to 2015). Database search yielded 1330 articles; after screening, exclusion, and further filtrations, 51 articles were included. Susceptibility to COVID-19 infection is related to the viral-microRNAs (miRNAs) which alter virulence of the transmitted SARS-CoV-2 strains and impact host-miRNA-related innate immunity. Host-DNA methylation and/or chromatin remodeling may be implicated in severe cytokine storm that can ultimately results in fatal outcome.Rapid urbanization and 'concretization' have increased the use of concrete as the preferred building material. However, the production of cement and other concrete-related activities, contribute significantly to both the carbon dioxide emissions and climate change. Agro-industrial wastes such as Palm Oil Fuel Ash (POFA) and Eggshell Powder (ESP) have been utilized in concrete as supplementary cementitious materials, to reduce the cement content, in order to minimize the carbon footprint and the environmental pollution associated with the dumping of waste. Both POFA and ESP have been utilized in ternary binder foamed concrete; however, higher content of cement replacement tends to reduce the concrete's strength significantly. Therefore, this research was conducted to study the influence of ternary binder foamed concrete, incorporating 30% POFA and 5-15% ESP by weight of the total binder, when reinforced with polypropylene (PP) fibres. Based on the results, the ternary binder foamed concrete showed better strength than the control foamed concrete due to the pozzolanic reaction and the addition of PP fibres slightly improved the strength. Furthermore, ternary binder foamed concrete can reduce up to 33.79% of the total CO2 emissions. In terms of cost, all ternary binder foamed concrete mixes reduced the overall cost of the mix. The lowest cost per 1 MPa was achieved by ternary binder foamed concrete mix which incorporated 30% POFA, 5% ESP and 0.20% PP fibres. However, the optimum S5 ternary binder foamed concrete mix, which incorporated 30% POFA, 10% ESP and 0.20% PP fibres, exhibited a cost of $3.74 per 1 MPa strength, which was $1.1 lower than the control foamed concrete. PP reinforced ternary binder foamed concrete is an eco-efficient and cost-effective concrete that can be used in numerous civil engineering applications, mitigating the environmental and the emissions generated by agro-industrial waste.Present study deals with the efficacy of nanoencapsulated Homalomena aromatica essential oil (HAEO) as a potent green preservative against toxigenic Aspergillus flavus strain (AF-LHP-NS 7), storage fungi, AFB1, and free radical-mediated deterioration of stored spices. GC-MS analysis revealed linalool (68.51%) as the major component of HAEO. HAEO was encapsulated into chitosan nanomatrix (CS-HAEO-Ne) and characterized through SEM, FTIR, and XRD. CS-HAEO-Ne completely inhibited A. flavus growth and AFB1 biosynthesis at 1.25 μL/mL and 1.0 μL/mL, respectively in comparison to unencapsulated HAEO (1.75 μL/mL and 1.25 μL/mL, respectively). CS-HAEO-Ne caused significant reduction in ergosterol content in treated A. flavus and provoked leakage of cellular ions (Ca+2, Mg+2, and K+) as well as 260 nm and 280 nm absorbing materials. Depletion of methylglyoxal level in treated A. flavus cells illustrated the novel antiaflatoxigenic efficacy of CS-HAEO-Ne. CS-HAEO-Ne exhibited superior antioxidant efficacy (IC50 (DPPH) = 4.5 μL/mL) over unencapsulated HAEO (IC50 (DPPH) = 15.9 μL/mL) and phenolic content. CS-HAEO-Ne depicted excellent in situ efficacy by inhibiting fungal infestation, AFB1 contamination, lipid peroxidation, and mineral loss with acceptable sensorial profile. Moreover, broad safety paradigm (LD50 value = 7150.11 mg/kg) of CS-HAEO-Ne also suggests its application as novel green preservative to enhance shelf life of stored spices.This study uses the output volatility-augmented environmental Kuznets curve (EKC) model to determine the dynamic short- and long-term impacts of the volatility of economic growth (VOL) on carbon dioxide (CO2) emissions in Turkey from 1980 to 2015. The results of the autoregressive distributed lag (ARDL) approach indicate that there is a long-run relationship between CO2, per capita real GDP, per capita energy use, and VOL. The coefficients obtained from the ARDL estimation indicate that economic growth and energy use increase CO2 emissions, while VOL decreases CO2 emissions in the long run. Moreover, the coefficients obtained from the ARDL error correction model show that VOL decreases CO2 emissions in the short run, as well. We also find that the EKC is valid in Turkey. This implies for the Turkish case that achieving macro-stability under a "just transition" is key for achieving both economic and environmental benefits from ratifying international agreements such as Paris Agreement and EU Green Deal.

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