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We propose a method of finding an optimal value of a main parameter, Eps-neighborhood (eps), which affects the accuracy of the resultant clusters. Simulation-based experiments show that the proposed method performs as if the number of new positions were known in advance. Furthermore, we clarify the timing of performing the new position candidate identification process, in which we propose criteria for qualifying a cluster as the one comprising a new position.Trend prediction based on sensor data in a multi-sensor system is an important topic. As the number of sensors increases, we can measure and store more and more data. However, the increase in data has not effectively improved prediction performance. This paper focuses on this problem and presents a distributed predictor that can overcome unrelated data and sensor noise First, we define the causality entropy to calculate the measurement's causality. Then, the series causality coefficient (SCC) is proposed to select the high causal measurement as the input data. To overcome the traditional deep learning network's over-fitting to the sensor noise, the Bayesian method is used to obtain the weight distribution characteristics of the sub-predictor network. A multi-layer perceptron (MLP) is constructed as the fusion layer to fuse the results from different sub-predictors. The experiments were implemented to verify the effectiveness of the proposed method by meteorological data from Beijing. The results show that the proposed predictor can effectively model the multi-sensor system's big measurement data to improve prediction performance.The efficiency of cooperative communication protocols to increase the reliability and range of transmission for Vehicular Ad hoc Network (VANET) is proven, but identity verification and communication security are required to be ensured. Though it is difficult to maintain strong network connections between vehicles because of there high mobility, with the help of cooperative communication, it is possible to increase the communication efficiency, minimise delay, packet loss, and Packet Dropping Rate (PDR). However, cooperating with unknown or unauthorized vehicles could result in information theft, privacy leakage, vulnerable to different security attacks, etc. In this paper, a blockchain based secure and privacy preserving authentication protocol is proposed for the Internet of Vehicles (IoV). Blockchain is utilized to store and manage the authentication information in a distributed and decentralized environment and developed on the Ethereum platform that uses a digital signature algorithm to ensure confidentiality, non-repudiation, integrity, and preserving the privacy of the IoVs. For optimized communication, transmitted services are categorized into emergency and optional services. Similarly, to optimize the performance of the authentication process, IoVs are categorized as emergency and general IoVs. The proposed cooperative protocol is validated by numerical analyses which show that the protocol successfully increases the system throughput and decreases PDR and delay. On the other hand, the authentication protocol requires minimum storage as well as generates low computational overhead that is suitable for the IoVs with limited computer resources.Acoustic event detection and analysis has been widely developed in the last few years for its valuable application in monitoring elderly or dependant people, for surveillance issues, for multimedia retrieval, or even for biodiversity metrics in natural environments. For this purpose, sound source identification is a key issue to give a smart technological answer to all the aforementioned applications. Diverse types of sounds and variate environments, together with a number of challenges in terms of application, widen the choice of artificial intelligence algorithm proposal. This paper presents a comparative study on combining several feature extraction algorithms (Mel Frequency Cepstrum Coefficients (MFCC), Gammatone Cepstrum Coefficients (GTCC), and Narrow Band (NB)) with a group of machine learning algorithms (k-Nearest Neighbor (kNN), Neural Networks (NN), and Gaussian Mixture Model (GMM)), tested over five different acoustic environments. This work has the goal of detailing a best practice method and evaluate the reliability of this general-purpose algorithm for all the classes. Preliminary results show that most of the combinations of feature extraction and machine learning present acceptable results in most of the described corpora. Nevertheless, there is a combination that outperforms the others the use of GTCC together with kNN, and its results are further analyzed for all the corpora.This paper presents the benefits of using the random-walk normalized Laplacian matrix as a graph-shift operator and defines the frequencies of a graph by the eigenvalues of this matrix. A criterion to order these frequencies is proposed based on the Euclidean distance between a graph signal and its shifted version with the transition matrix as shift operator. Further, the frequencies of a periodic graph built through the repeated concatenation of a basic graph are studied. We show that when a graph is replicated, the graph frequency domain is interpolated by an upsampling factor equal to the number of replicas of the basic graph, similarly to the effect of zero-padding in digital signal processing.Unapproved ingredients included in herbal medicines and dietary supplements have been detected as adulterated synthetic drugs used for erectile dysfunction. Extraction from a dietary supplement was performed to isolate the compounds by HPLC analysis. Selleck XL765 The structural characterization was confirmed using mass spectrometry (ESI-TOF/MS and LC-MS/MS), 1H NMR, and 13C NMR spectroscopy techniques. Results identified the thus-obtained compound to be sulfoaildenafil, a thioketone analogue of sildenafil. The biological activities of this active compound have been focused for the first time by the experimental point of view performance in vitro. The results revealed that sulfoaildenafil can affect the therapeutic level of nitric oxide through the upregulation of nitric oxide synthase and phosphodiesterase type 5 (PDE5) gene expressions. This bulk material, which displays structural similarity to sildenafil, was analyzed for the presence of a PDE5 inhibitor using a theoretical calculation. These unique features of the potential activity of PDE5 protein and its inhibitors, sildenafil and sulfoaildenafil, may play a key consideration for understanding the mode of actions and predicting the biological activities of PDE5 inhibitors.

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