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The effects of the inhibitors on this characteristic were mixed, but each of the inhibitor pairs yielded potential differences in excess of 100 mV. A conceptual conversion coating process based on a mixture of vanadate and phosphate compounds were demonstrated. A fluoride-bearing formulation produced coatings whose total impedance was increased by a factor of two compared to an uncoated control. A fluoride-free formulation produced coatings whose corrosion resistance was increased by more than a factor of three.Driver behavior has been considered as the most critical and uncertain criteria in the study of traffic safety issues. Driver behavior identification and categorization by using the Fuzzy Analytic Hierarchy Process (FAHP) can overcome the uncertainty of driver behavior by capturing the ambiguity of driver thinking style. The main goal of this paper is to examine the significant driver behavior criteria that influence traffic safety for different traffic cultures such as Hungary, Turkey, Pakistan and China. The study utilized the FAHP framework to compare and quantify the driver behavior criteria designed on a three-level hierarchical structure. The FAHP procedure computed the weight factors and ranked the significant driver behavior criteria based on pairwise comparisons (PCs) of driver's responses on the Driver Behavior Questionnaire (DBQ). The study results observed "violations" as the most significant driver behavior criteria for level 1 by all nominated regions except Hungary. While for level 2, "aggressive violations" is observed as the most significant driver behavior criteria by all regions except Turkey. Moreover, for level 3, Hungary and Turkey drivers evaluated the "drive with alcohol use" as the most significant driver behavior criteria. While Pakistan and China drivers evaluated the "fail to yield pedestrian" as the most significant driver behavior criteria. Finally, Kendall's agreement test was performed to measure the agreement degree between observed groups for each level in a hierarchical structure. The methodology applied can be easily transferable to other study areas and our results in this study can be helpful for the drivers of each region to focus on highlighted significant driver behavior criteria to reduce fatal and seriously injured traffic accidents.Perioperative factors promoting cancer recurrence and metastasis are under scrutiny. While oxygen toxicity is documented in several acute circumstances, its implication in tumor evolution is poorly understood. We investigated hyperoxia long-term effects on cancer progression and some underlying mechanisms using both in vitro and in vivo models of triple negative breast cancer (TNBC). We hypothesized that high oxygen exposure, even of short duration, may have long-term effects on cancer growth. Considering that hyperoxic exposure results in reactive oxygen species (ROS) formation, increased oxidative stress and increased Brain-Derived Neurotrophic Factor (BDNF) expression, BDNF may mediate hyperoxia effects offering cancer cells a survival advantage by increased angiogenesis and epithelial mesenchymal transition (EMT). Human breast epithelial MCF10A, human MDA-MB-231 and murine 4T1 TNBC were investigated in 2D in vitro system. Cells were exposed to normoxia or hyperoxia (40%, 60%, 80% O2) for 6 h. We evaluated ROS levels, cell viability and the expression of BDNF, HIF-1α, VEGF-R2, Vimentin and E-Cadherin by immunofluorescence. The in vivo model consisted of 4T1 inoculation in Balb/c mice and tumor resection 2 weeks after and 6 h exposure to normoxia or hyperoxia (40%, 80% O2). We measured lung metastases and the same molecular markers, immediately and 4 weeks after surgery. The in vitro study showed that short-term hyperoxia exposure (80% O2) of TNBC cells increases ROS, increases BDNF expression and that promotes EMT and angiogenesis. https://www.selleckchem.com/products/kb-0742-dihydrochloride.html The in vivo data indicates that perioperative hyperoxia enhances metastatic disease and this effect could be BDNF mediated.Fruit consumption is recommended as part of a healthy diet. However, consumption of fruit in the form of juice is positively associated with type 2 diabetes risk, possibly due to resulting hyperglycemia. In a recent study, fruit juice prepared by nutrient extraction, a process that retains the fiber component, was shown to elicit a favorable glycemic index (GI), compared to eating the fruit whole, in healthy weight adults. The current study expanded on this to include individuals with obesity, and assessed whether the nutrient extraction of seeded fruits reduced GI in a higher disease risk group. Nutrient extraction was shown to significantly lower GI, compared to eating fruit whole, in subjects with obesity (raspberry/mango 25.43 ± 18.20 vs. 44.85 ± 20.18, p = 0.034 and passion fruit/mango (26.30 ± 25.72 vs. 42.56 ± 20.64, p = 0.044). Similar results were found in those of a healthy weight. In summary, the current study indicates that the nutrient-extraction of raspberries and passionfruit mixed with mango lowers the GI, not only in healthy weight individuals, but also in those with obesity, and supports further investigation into the potential for nutrient extraction to enable increased fruit intake without causing a high glycemic response.The oxidation process of samariumoxysulfide was studied in the temperature range of 500-1000 °C. Our DTA investigation allowed for establishing the main thermodynamic (∆Hºexp = -654.6 kJ/mol) and kinetic characteristics of the process (Ea = 244 kJ/mol, A = 2 × 1010). The enthalpy value of samarium oxysulfate (ΔHºf (Sm2O2SO4(monocl)) = -2294.0 kJ/mol) formation was calculated. The calculated process enthalpy value coincides with the value determined in the experiment. It was established that samarium oxysulfate crystallizes in the monoclinic symmetry class and its crystal structure belongs to space group C2/c with unit cell parameters a = 13.7442 (2), b = 4.20178 (4) and c = 8.16711 (8)Å, β = 107.224 (1)°, V = 450.498 (9)Å3, Z = 4. The main elements of the crystalline structure are obtained and the cation coordination environment is analyzed in detail. Vibrational spectroscopy methods confirmed the structural model adequacy. The Sm2O2SO4luminescence spectra exhibit three main bands easily assignable to the transitions from 4G5/2 state to 6H5/2, 6H7/2, and 6H9/2 multiplets.