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The tests can be useful as intermediate resolution typing for solid organ transplantation.

Lymphoma is a malignancy of hematopoietic and lymphoid tissues. selleck chemical Early diagnosis of lymphoma is very important and could save patients' lives. Nevertheless, the diagnosis of lymphoma could be difficult in the presence of complex manifestations and a lack of convincing laboratory findings. Here we report a case of large B cell lymphoma misdiagnosed as hemophagocytic syndrome during the hospitalization and treatment course.

Retrospective review of patient's clinical data, differential diagnosis, and treatment were performed. Patient's disease course was followed and the final diagnosis, along with relevant discussions and summaries were documented.

This report may be helpful in the diagnosis of lymphoma with complex manifestations differentiated from hemophagocytic syndrome, and may facilitate early diagnosis and treatment.

This report may be helpful in the diagnosis of lymphoma with complex manifestations differentiated from hemophagocytic syndrome, and may facilitate early diagnosis and treatment.

Knowing the prevalence of blood group antigens in a given population is important to prevent hemolytic reactions. The Duffy blood group system (FY) has two main antigens, Fya and Fyb. Antibodies binding these antigens can cause immediate/delayed hemolytic transfusion reactions as well as hemolytic disease of the fetus and newborn. In this study, frequencies of Fya and Fyb antigen expression and FY phenotypes were determined in a cohort of Saudi blood donors.

For this study, 143 samples were collected from randomly selected volunteer Saudi blood donors living in Jazan Province. Serological analysis, using gel card technology, was performed to detect Fya and Fyb antigens among the samples.

The frequencies of Fya and Fyb antigens were 12.58% and 11.18%, respectively. The numbers and frequencies of FY phenotypes were as follows Fy(a+b-), 15 (10.48%); Fy(a-b+), 13 (9.10%); Fy(a+b+), 3 (2.10%), and Fy(a-b-), 112 (78.32%). The frequencies of the FY phenotypes were highly and significantly different in Jazan Saudis compared to other ethnicities (< 0.01).

This study reports the frequencies of the Fya and Fyb antigens and phenotypes of the FY blood group system in the Kingdom of Saudi Arabia's Jazan Province. The null phenotype Fy(a-b-) was the most prevalent among this population. This study highlights the importance of investigating FY alleles in different provinces of the Kingdom of Saudi Arabia.

This study reports the frequencies of the Fya and Fyb antigens and phenotypes of the FY blood group system in the Kingdom of Saudi Arabia's Jazan Province. The null phenotype Fy(a-b-) was the most prevalent among this population. This study highlights the importance of investigating FY alleles in different provinces of the Kingdom of Saudi Arabia.

Vitamin D deficiency is common during pregnancy. 25(OH)-Vitamin D3 is the major vitamin D circulating form in human organism. However, the effects of 25(OH)-vitamin D3 deficiency in late pregnancy on the infant's amino acid metabolism has still not been studied. The aim of this study was to evaluate the relationship between maternal serum 25(OH)-vitamin D3 levels in late pregnancy and profiles of newborn amino acid concen-trations.

A total of 539 women in late pregnancy and their newborns enrolled in this study. The concentrations of 25(OH)-vitamin D3 in maternal serum were measured by ABI 4500 high performance liquid chromatography tandem mass spectrometry (HPLC/MS/MS). For newborns, their amino acids levels were measured by ABI 3200 LC/MS/MS. T-test and Spearman's correlation analyses were used in the study as statistical analysis methods.

The concentrations of arginine (Arg) and glycine (Gly) in newborn blood spots were significantly different in each maternal serum 25(OH)-vitamin D3 status group. There was a significant correlation between maternal serum 25(OH)-vitamin D3 status and Arg concentration in their offspring (p = 0.03).

Maternal serum 25(OH)-vitamin D3 concentration in late pregnancy may affect their newborn's amino acid metabolism, but the precise mechanisms underlying the relationship need further investigation.

Maternal serum 25(OH)-vitamin D3 concentration in late pregnancy may affect their newborn's amino acid metabolism, but the precise mechanisms underlying the relationship need further investigation.

To explore the effects of isovolumic hemodilution and platelet-rich plasma separation on platelet activation state and function, complications, and inflammation in patients undergoing cardiac surgery.

A total of 80 patients who needed cardiac surgery under extracorporeal circulation from February 2018 to December 2019 in our hospital were selected as research subjects and divided into observation group (n = 40) and control group (n = 40) according to the random number table method. The patients in the observation group underwent platelet-rich plasma separation, while those in control group received acute isovolumic hemodilution. Then the platelet activation state and functional indexes, hemorheological indexes, and the coagulation functional indexes were compared between the two groups of patients before operation. Next, the changes in the levels of hemoglobin and high-sensitivity C-reactive protein (hs-CRP), an inflammatory factor, during blood protection (before and at 6 hours and 12 hours after interve allogeneic blood infusion, with fewer adverse reactions in treatment, thus efficaciously facilitating the post-operative recovery of patients.

For patients undergoing cardiac surgery under extracorporeal circulation, platelet-rich plasma separation and reinfusion technology can effectively ensure platelet activation state and function, reduce blood viscosity, ensure stable coagulation function, elevate hemoglobin level and decrease inflammatory reaction, and perioperative allogeneic blood infusion, with fewer adverse reactions in treatment, thus efficaciously facilitating the post-operative recovery of patients.

The study was aimed to compare ELISA results of Mycoplasma pneumoniae IgG (MP-IgG) and Mycoplasma pneumoniae IgM (MP-IgM) with the passive particle agglutination (PA) test, as well as to evaluate their application value in the diagnosis of Mycoplasma pneumoniae pneumonia (MPP) in children.

Serum MP antibodies were detected by ELISA for MP-IgM, MP-IgG, and PA for 292 patients in the MPP group and 89 patients in NMP group. The PA results were used as reference standards. These patients were treated in the respiratory department of Children's Hospital Capital Institute of Pediatrics, China, from July to December, 2019.

In the MPP group, the positive rate for MP-IgM was 75% higher than that of the PA titer (73.97%), Pearson's coefficient was 0.711, and the Kappa coefficient was 0.662, p < 0.01, suggesting that both the correlation and the consistency of the two methods were high. In the PA-negative group (< 1160), 22.38% of patients were MP-IgM positive, indicating that the sensitivity to MP-IgM was higher compared to PA, when the disease duration was less than 7 days.