Clemensenewing8350
To evaluate the association of dental pain with time living on the street in a sample of homeless people in the city of Porto Alegre, Brazil.
A cross-sectional study was carried out with homeless people who accessed social services in 2017. this website A questionnaire was administered covering socioeconomic variables and including questions about general health, use of tobacco/alcohol/drugs, use of dental services and history of dental pain. The decayed, missing, and filled teeth (DMFT) index was calculated in an oral examination. The association between socioeconomic characteristics, health status, time of homelessness and dental pain was evaluated using chi-square, t-, and Mann-Whitney tests.
A total sample of 214 homeless people was surveyed. Most were male (76.2%), had a low level of education (67.6%) and experienced many episodes of dental pain during life (91.0%). The last episode of pain was moderate or intense (79.7%) and do-it-yourself measures for pain relief were preferred (62.3%). Individuals who were homeless for longer than 1 year had more dental pain in the past (P < 0.001), more frequency of a recent episode of dental pain (P = 0.03), and sought a dentist or healthcare service to relieve pain less frequently (P = 0.03).
Dental pain is frequent in the context of homelessness and does not necessarily result in seeking dental services, even where there is universal oral health care.
Dental pain is frequent in the context of homelessness and does not necessarily result in seeking dental services, even where there is universal oral health care.
The efficacy of conventional systemic antibiotic therapy for eradication of Helicobacter pylori has been seriously challenged by antibiotic resistance. Identification of alternative therapeutic strategies might help to overcome this limitation. The aim of this study was to update previous meta-analyses that investigated the effect of periodontal treatment on gastric H. pylori eradication.
A systematic electronic search of the literature was conducted to identify all published clinical trials that compared the effect of adjunct periodontal treatment on conventional systemic H. link2 pylori eradication therapy.
The updated analysis (consisting of 541 participants representing six studies) demonstrated that, compared with conventional systemic eradication therapy alone, the addition of periodontal treatment resulted in improvements in gastric H. pylori eradication rates with OR 4.11 (P = 0.01). Moreover, not to lose any data, the previously presented Chinese results that could not be assessed by any available messional periodontal treatment with systemic eradication therapy may be a wise strategy, enhancing the efficacy of H. pylori eradication therapy. Systematic review registration in PROSPERO ID number CRD42019119347.
Although the inclusion of five additional clinical trials in this updated meta-analysis has not changed the result of the previous review, the current meta-analysis is superior for having removed one study involving the use of chlorhexidine, which did not meet appropriate criteria for inclusion. Our results strengthen the value of periodontal treatment as an adjunctive remedy. Consistency of these results suggests that the incorporation of professional periodontal treatment with systemic eradication therapy may be a wise strategy, enhancing the efficacy of H. pylori eradication therapy. Systematic review registration in PROSPERO ID number CRD42019119347.Gingival recession is a common finding in daily clinical practice. Several issues may be associated with the apical shift of the gingival margin such as dentine hypersensitivity, root caries, non-carious cervical lesions (NCCLs), and compromised aesthetics. The first step in an effective management and prevention program is to identify susceptibility factors and modifiable conditions associated with gingival recession. Non-surgical treatment options for gingival recession defects include establishment of optimal plaque control, removal of overhanging subgingival restorations, behaviour change interventions, and use of desensitising agents. In cases where a surgical approach is indicated, coronally advanced flap and tunnelling procedures combined with a connective tissue graft are considered the most predictable treatment options for single and multiple recession defects. If there is a contraindication for harvesting a connective tissue graft from the palate or the patient wants to avoid a donor site surgery, adjunctive use of acellular dermal matrices, collagen matrices, and/or enamel matrix derivatives can be a valuable treatment alternative. For gingival recession defects associated with NCCLs a combined restorative-surgical approach can provide favourable clinical outcomes. If a patient refuses a surgical intervention or there are other contraindications for an invasive approach, gingival conditions should be maintained with preventive measures. This paper gives a concise review on when and how to treat gingival recession defects.
Approximately half of all patients with tumors need radiotherapy. Long-term survivors may suffer from late sequelae of the treatment. The existing radiotherapeutic techniques are being refined so that radiation can be applied more precisely, with the goal of limiting the radiation exposure of normal tissue and reducing late sequelae.
This review is based on the findings of a selective search in PubMed for publications on late sequelae of conventional percutaneous radiotherapy, January 2000 to May 2020. Late sequelae affecting the central nervous system, lungs, and heart and the development of second tumors are presented, and radiobiological mechanisms and the relevant technical and conceptual considerations are discussed.
The current standard of treatment involves the use of linear accelerators, intensity-modulated radiotherapy (IMRT), image-guided and respiratory-gated radiotherapy, and the integration of positron emission tomography combined with computed tomography (PET-CT) in radiation treatment pla the areas of adaptive radiotherapy, proton and heavy-ion therapy, and personalized therapy.
Special challenges for research in this field arise from the long latency of radiation sequelae and the need for largescale, well-documented patient collectives in order to discern dose-effect relationships, and take account of cofactors, when the overall number of events is small. It is hoped that further technical and conceptual advances will be made in the areas of adaptive radiotherapy, proton and heavy-ion therapy, and personalized therapy.
Increasing digitalization enables the use of artificial intelligence (AI) and machine learning in pathology. However, these technologies have only just begun to be implemented, and no randomized prospective trials have yet shown a benefit of AI-based diagnosis. In this review, we present current concepts, illustrate them with examples from representative publications, and discuss the possibilities and limitations of their use.
This article is based on the results of a search in PubMed for articles published between January 1950 and January 2020 containing the searching terms "artificial intelligence," "deep learning," and "digital pathology," as well as the authors' own research findings.
Current research on AI in pathology focuses on supporting routine diagnosis and on prognostication, particularly for patients with cancer. Initial data indicate that pathologists can arrive at a diagnosis faster and more accurately with the aid of a computer. In a pilot study on the diagnosis of breast cancer, involving 70 patients, sensitivity for the detection of micrometastases rose from 83.3% (by a pathologist alone) to 91.2% (by a pathologist combined with a computer algorithm). The evidence likewise suggests that AI applied to histomorphological properties of cells during microscopy may enable the inference of certain genetic properties, such as mutations in key genes and deoxyribonucleic acid (DNA) methylation profiles.
Initial proof-of-concept studies for AI in pathology are now available. Randomized, prospective studies are now needed so that these early findings can be confirmed or falsified.
Initial proof-of-concept studies for AI in pathology are now available. Randomized, prospective studies are now needed so that these early findings can be confirmed or falsified.
The occurrence of venous thromboembolisms (VTE) in association with sporting activity has been described but not yet systematically explored. The aim of this study was to determine the sites at which VTE occur in athletes, the accompanying features, and the special features of the symptoms and diagnosis, so that physicians can take the findings into consideration.
A search of the literature in the databases PubMed, Web of Science, and Cochrane in accordance with the PRISMA criteria, together with a search of Google Scholar up to 29 February 2020.
No observational studies were identified. A total of 154 case descriptions were evaluated 89 on upper-extremity deep vein thrombosis (DVT), 53 on lower-extremity DVT, and 12 on pulmonary embolisms with no evidence of thrombosis. Ninety-five percent of the upper-extremity DVT involved the region of the subclavian/axillary vein. link3 Thoracic outlet syndrome (38%), hereditary thrombophilia/a family history of VTE (16%), intensive training (12%), and the use of oral coT must be borne in mind.
VTE are found in association with sports. The background factors, the sites of VTE, the types of sports involved, and the accompanying features are all important to know. The symptoms may be obscured, and it may be difficult to reach the correct diagnosis. The possible presence of DVT must be borne in mind.
Pre-eclampsia affects around 2-3% of all pregnancies, and is associated with potential serious complications for the woman and the baby. Once diagnosed, progression of the syndrome can be unpredictable, and decisions around timing of delivery need to take into account evolving maternal complications and perinatal morbidity. Novel prognostic models and blood biomarkers for determination of need for delivery in pregnancies with pre-eclampsia are now emerging.
The objective of the study was to establish a prognostic model to inform optimal timing of delivery in women with late preterm pre-eclampsia (34
to 36
weeks' gestation), comparing novel candidate biomarkers (e.g. placental growth factor) with clinical and routinely collected blood/urinary parameters [incorporated into the PREP-S (Prediction models for Risk of Early-onset Pre-eclampsia - Survival) model] to determine clinically indicated need for delivery for pre-eclampsia (or related complications) within 7 days of assessment.
Prospective recruitealth Research (NIHR) Health Technology Assessment programme and will be published in full in
; Vol. 25, No. 30. See the NIHR Journals Library website for further project information.
This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 25, No. 30. See the NIHR Journals Library website for further project information.Compassion fatigue (CF) has been described in various "caring professions," particularly the human medical field. Recently, CF has been identified as a concern in animal care professions, specifically veterinary medicine. Despite the perception that veterinary personnel in animal research are at increased risk of CF, few studies have assessed CF in this population. The current cross-sectional study aimed to describe the prevalence of both CF and compassion satisfaction (CS) among active-duty veterinary personnel in Department of Defense animal research environments, using the Professional Quality of Life Scale (ProQOL). The ProQOL measures burnout and secondary traumatic stress as representative of compassion fatigue, while also measuring the inverse of CF, or CS. The current study set out to identify factors associated with both CF and CS. Validated scales of measurement were used to assess the frequency of exposures and outcomes of interest, while associations were analyzed using linear regression models. The study found that most survey respondents reported high levels of CS and low levels of BO and STS.
