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23.] PLAIN LANGUAGE SUMMARY This study describes health literacy research funded by the National Institutes of Health that focused on disease prevention. These grants sought to prevent a variety of health conditions, but health literacy research over the past 14 years continued to concentrate on the capacity of patients despite increased attention on the health literacy practices of health care providers and systems.

To describe the visual outcomes of correcting moderate to high hyperopia after two different surgical procedures of lenticular implantation.

This prospective small case series study used epikeratophakia combined with transepithelial phototherapeutic keratectomy (PTK-EP) and femtosecond laser-assisted lenticule intrastromal keratoplasty (LIKE) using myopic small incision lenticule extraction (SMILE)-derived refractive lenticule for correcting hyperopia ranging from +3.00 to +10.00 diopters (D). The implanted refractive lenticule was matched with the recipient's manifest refraction. The visual, refractive, corneal tomographic, and epithelial thickness outcomes were analyzed after surgery.

Four eyes underwent PTK-EP and 6 eyes underwent LIKE. At the last postoperative visit, 6 of 10 eyes had uncorrected distance visual acuity equal to or better than the preoperative corrected distance visual acuity (CDVA). No eyes lost one line or more of CDVA postoperatively. Postoperative spherical equivalent was within ±0.50 D of the target for 9 of 10 eyes. Posterior corneal curvature slightly steepened for PTK-EP and LIKE. Postoperative epithelial thickness demonstrated the expected doughnut pattern in both groups characterized by epithelium in the central zone (5 mm) thinner than that in the peripheral zone (5 to 7 mm).

Visual outcomes, refraction, posterior corneal surface changes, and epithelial remodeling after PTKEP or LIKE show a potentially useful modality for correcting moderate to high hyperopia. [J Refract Surg. 2020;36(11)772-779.].

Visual outcomes, refraction, posterior corneal surface changes, and epithelial remodeling after PTKEP or LIKE show a potentially useful modality for correcting moderate to high hyperopia. [J Refract Surg. 2020;36(11)772-779.].

To describe the use of topography-guided custom ablation treatment with photorefractive keratectomy (T-CAT PRK) to correct irregular astigmatism and visual aberrations resulting from decentered small incision lenticule extraction (SMILE).

Case report and literature review.

A 41-year-old woman experienced blurred uncorrected distance acuity (UDVA), reduced corrected distance acuity (CDVA), and monocular diplopia in one eye following SMILE due to treatment decentration. this website Retrospective review of the surgical video provided visual cues to the impending decentration at multiple points during the docking process and lenticule creation. Re-treatment was performed using T-CAT PRK with mitomycin C application with off-label use of the EX500 excimer laser (Alcon Laboratories, Inc). Treatment resulted in improvement in UDVA and CDVA to 20/12; reduced higher order aberrations, particularly vertical coma (-0.65 µm to 0.197 µm); topographic pattern centration; and subjective symptom resolution.

Recognition of subtle visual cues at the time of SMILE docking can provide critical feedback to avoid treatment decentration. T-CAT PRK can be a useful treatment option when decentration occurs. [J Refract Surg. 2020;36(11)766-771.].

Recognition of subtle visual cues at the time of SMILE docking can provide critical feedback to avoid treatment decentration. T-CAT PRK can be a useful treatment option when decentration occurs. [J Refract Surg. 2020;36(11)766-771.].

To develop a coincident thinning (CTN) index to differentiate between keratoconic and healthy corneas using optical coherence tomography (OCT) measurements of pachymetry and epithelial thickness.

Pattern deviation maps of pachymetry and epithelial thickness were generated using Fourier-domain OCT images of the cornea. The co-localized thinning of the two maps was quantified using a novel CTN index, which was calculated from Gaussian fits of the regions of maximum relative thinning. The CTN index was validated using k-fold cross-validation, and its classification performance was compared to minimum pachymetry and maximum keratometry.

A total of 82 normal eyes and 133 eyes within three groups of keratoconus severity were evaluated. The pattern deviation maps for the keratoconic eyes showed relative thinning that was larger in magnitude and more strongly correlated with the Gaussian function compared to normal eyes (all P < .01). The distance between the pachymetric and epithelial maximum relative thinning locations was significantly smaller for the keratoconic eyes than for the normal eyes (all P < .02). The CTN index was significantly larger for all three keratoconus groups compared to normal eyes (all P < .0001). The CTN index demonstrated a sensitivity of 100% in detecting manifest keratoconus, 100% for subclinical keratoconus, and 56% for forme fruste keratoconus. The overall classification accuracy was better for the CTN index (93%) than for minimum pachymetry (86%) and maximum keratometry (86%).

The CTN index is a highly sensitive measure of coincident pachymetric and epithelial thinning. It provides valuable information for detecting and monitoring early to moderate keratoconus. [J Refract Surg. 2020;36(11)757-765.].

The CTN index is a highly sensitive measure of coincident pachymetric and epithelial thinning. It provides valuable information for detecting and monitoring early to moderate keratoconus. [J Refract Surg. 2020;36(11)757-765.].

To evaluate the distribution of pupil size in patients implanted with multifocal intraocular lenses (IOLs) and to assess the variations according to age.

A total of 168 eyes that had implantation of several multifocal IOLs and were measured at the 3-month follow-up visit were included in the analysis. The Keratograph 5M (Oculus Optikgeräte) was used to measure the photopic and mesopic pupil size, as well as the average between both (average pupil size). Eyes were stratified in four groups by age 50 years or younger, 51 to 60 years, 61 to 70 years, and older than 70 years.

Considering the total sample, 84.5% and 95.8% of eyes had a photopic pupil size of 3 and 3.5 mm or less, respectively. The mesopic pupil size was greater than 4.5 mm in 39.3% and greater than 5 mm in 16.7% of eyes. The average pupil size was 3.5 and 4 mm or less in 54.2% and 85.1% of eyes, respectively. Mesopic pupil size resulted in a steeper decrease with age than photopic pupil size 0.028 versus 0.015 mm/year, respectively. Statistically significant differences were found among the four age groups (P < .

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