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People living alone had a significantly higher risk of depression, increased loneliness and lack of social support.

Assessments were based on self-reporting and recorded dimensionally. The cross-sectional design limits conclusions about directions and causality of associations. Sampling bias cannot be completely excluded.

The study provides empirical evidence and a better understanding of the association between grief and depression among the very old and the mediating role of loneliness.

The study provides empirical evidence and a better understanding of the association between grief and depression among the very old and the mediating role of loneliness.

This study examined whether expressive suppression (ES), a maladaptive regulation strategy, was more strongly associated with PTSD diagnosis and symptom clusters in veterans than cognitive reappraisal (CR), an adaptive regulation strategy.

In a cohort study, 746 participants recruited from VHA facilities completed Clinician Administered PTSD Scale-IV, Emotion Regulation Questionnaire, and Patient Health Questionnaire. Evobrutinib datasheet Participants were categorized into groups Current, Remitted/Lifetime, and Never PTSD.

One-way ANOVA revealed significant differences between Current PTSD and both Remitted and Never PTSD for ES, but not CR. The Remitted and Never PTSD groups did not vary significantly from each other and were collapsed into one group for regressions. Adjusting for sex, race, employment, and comorbid depression, binary logistic regression showed ES, but not CR, was associated with increased likelihood of Current PTSD (p < .001, OR 1.43). ES was also significantly associated with increased odds of meeting criteria for all symptom clusters (ps < 0.001). CR was not significantly associated with meeting criteria for Current PTSD or any symptom cluster.

Cross-sectional design and use of self-report limit causality inferences that can be drawn.

ES is associated with increased odds of Current PTSD diagnosis and symptom clusters. Veterans in the Remitted and Never PTSD groups did not differ significantly. Greater suppression of emotional expression is more strongly linked with PTSD criteria in veterans than decreased cognitive reappraisal.

ES is associated with increased odds of Current PTSD diagnosis and symptom clusters. Veterans in the Remitted and Never PTSD groups did not differ significantly. Greater suppression of emotional expression is more strongly linked with PTSD criteria in veterans than decreased cognitive reappraisal.

To prospectively investigate relationships of cortical somatosensory evoked potential (SEP) amplitudes with consciousness recovery and disability in the year following brain injury in patients with vegetative state/unresponsive wakefulness syndrome (VS/UWS).

SEPs of 42 patients with VS/UWS were recorded 51.7±23.3days post-injury. N20-P25 amplitudes were compared between patients with and without consciousness recovery at 6months and 1year post-injury.

SEPs were present in 21 patients and bilaterally absent in 21 patients. N20-P25 amplitudes were significantly higher in patients who recovered consciousness than in those who died or did not recover consciousness at 6months (median, 4.6 vs. 1.9μV; P=0.004) and 1year (median, 4.6 vs. 2.1μV; P=0.02) after injury. The lowest N20-P25 amplitude in a patient who recovered consciousness was 2.15μV. N20-P25 amplitudes correlated significantly with Coma Recovery Scale-Revised and Disability Rating Scale scores at 6months and 1year post-injury (both P<0.05).

In patients with VS/UWS, SEP amplitudes are related to consciousness recovery and disability at 6months and 1year post-injury.

The evaluation of SEP amplitudes can help to refine prognoses for patients with VS/UWS.

The evaluation of SEP amplitudes can help to refine prognoses for patients with VS/UWS.

The presence of a cochlear implant is being considered an absolute contraindication for experiments and/or treatments. We aimed to verify TMS (Transcranial Magnetic Stimulation) compatibility of a new generation of cochlear implants.

In a series of experiments, we test if MED-EL cochlear implants -compatible with stable fields of magnetic resonance imaging scanning- are fully resistant even to rapidly varying magnetic fields as those generated by single pulses and low and high-frequency trains of repetitive TMS (rTMS) applied with a figure of eight coil and different magnetic stimulators.

With a TMS intensity equal or below 2.2 Tesla (T) the cochlear implant and all its electronic components remain fully functional, even when the combination of frequency, intensity and number of pulses exceeds the currently available safety guidelines. Induced forces on the implant are negligible. With higher magnetic fields (i.e., 3.2T), one device was corrupted.

Results exclude the risk of electronic damaging, demagnetizing or displacements of the studied cochlear implants when exposed to magnetic fields of up to 2.2T delivered through a focal coil.

They open the way to use focal rTMS protocols with the aim of promoting neural plasticity in auditory networks, possibly helping the post-implant recovery of speech perception performance.

They open the way to use focal rTMS protocols with the aim of promoting neural plasticity in auditory networks, possibly helping the post-implant recovery of speech perception performance.

Recently, it was shown that Group B Streptococcus (GBS) COH1 strain, which has granadaene-an endogenous chromophore known to absorb blue light-is not susceptible to 450nm pulsed blue light (PBL) inactivation unless the bacterium is co-cultured with exogenous porphyrin.

To confirm or refute the finding, we studied the effect of blue light on NCTC, another strain of GBS with more granadaene than COH1, to determine if the abundance of granadaene-and by implication more absorption of blue light-fosters GBS susceptibility to PBL.

We irradiated cultures of the bacterium with or without protoporphyrin, coproporphyrin, flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD), nicotinamide adenine dinucleotide (NAD) or NADH. After 24-h incubation, bacterial colonies were enumerated, log

CFU/mL computed, and descriptive and inferential data analyzed and compared.

(1) The rich amount of granadaene in NCTC did not enhance its susceptibility to antimicrobial pulsed blue light (PBL). (2) Adding exogenous porphyrin fostered NCTC susceptibility to irradiation, resulting in 100% bacterial suppression.

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