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57%). The mean diameter of the stone was 11.47 ±3.33mm whereas most of the stones were on the right side 16 (57.15%). The mean hardness was 1155.21±265.34 Hounsfield units. Perioperative complications like failed access sheath placement in 2 (7.14%) cases, hematuria in 6 (21.43%) cases, fever in 6 (21.43%) cases, and septicemia in 4 (14.28%) cases.

We found that the success rate of retrograde intrarenal surgery for the renal stone was acceptable and similar to other published studies . Retrograde intrarenal surgery is feasible for the treatment of kidney stones with acceptable complications and success rates.

We found that the success rate of retrograde intrarenal surgery for the renal stone was acceptable and similar to other published studies . Retrograde intrarenal surgery is feasible for the treatment of kidney stones with acceptable complications and success rates.

Spectrum of kidney diseases differs significantly in developing and developed countries. However, there is no central registry regarding the nature of such diseases in Nepal and our center either. The study aims to know the clinicodemographic spectrum of kidney disease patients admitted to our hospital.

This study was a descriptive cross sectional study done in the department of Nephrology, College of Medical Sciences Teaching Hospital from May 2018 to April 219. Convenient sampling was done and all the consecutive kidney disease patients irrespective of their age, sex, and renal diagnosis were included in the study. Ethical approval was taken from the Institutional Review Committee of the college (reference number. 2016/COMSTH/IRC/049). Clinicodemographic profile of kidney diseases were studied using statistical package for the social sciences version 20 and were represented as mean, standard deviation, number, percentage and ratio.

Out of a total of 829 patients, the commonest clinical syndrome and the histological patterns were end-stage renal disease 248 (29.9%) and IgA nephropathy 18 (20.7%) respectively. The mean age was 51.4±18.6 years. The commonest reason for hospitalization was sepsis 372 (44.8%). Males were 486 (58.6%) and females were 343 (41.4%).

The commonest clinical presentation and the reason for admissions were end-stage renal disease and sepsis syndrome respectively.

The commonest clinical presentation and the reason for admissions were end-stage renal disease and sepsis syndrome respectively.

The sedentary lifestyle of women and change in their food habits has a significant role in developing diabetes in pregnancies. This leads to an increased chance of fetal cardiac abnormality born by a mother with gestational diabetes and pre-existing diabetes. The objective of the study is to find out the prevalence of abnormal fetal echocardiography in gestational and pre-existing diabetic pregnant women at a tertiary care hospital.

A descriptive cross-sectional study was conducted among 104 diabetic pregnant women in a tertiary care hospital from April 15, 2017, to April 14, 2018. Ethical approval was obtained from the institutional review committee. The convenient sampling method was used. The patients who were diagnosed as gestational diabetes and diabetic before pregnancy were included in the study. Fetal echocardiography was mainly done at a gestational age of 22-32 weeks depending upon the time of diagnosis of gestational diabetes and for pre-diabetic women, fetal echocardiography was done at 24-26 weeks of gestation. Statistical analysis was done using the Statistical Package of the Social Sciences version 20.

Among 104 patients, 16 (15.38%) patients had abnormal fetal echocardiography. Eighty-three (79.81%) were gestational diabetics, 21 (20.19%) were pre-existing diabetic women. Among 83 gestational diabetes, 7 (8.4%) had abnormal echo finding and among 21 pre-existing diabetics, 9 (42.8%) had abnormal echo finding.

There was an increased chance of fetal cardiac malformation in gestational diabetic and pre-existing diabetics diabetic especially in an uncontrolled glycemic state. And, if they were diagnosed prenatally, clinical outcomes for both mother and fetus would have been better.

There was an increased chance of fetal cardiac malformation in gestational diabetic and pre-existing diabetics diabetic especially in an uncontrolled glycemic state. And, if they were diagnosed prenatally, clinical outcomes for both mother and fetus would have been better.

Cervical cancer is one of the most common cancer among the female population in Nepal. The incidence and mortality rate due to cervical cancer is higher in developing countries like Nepal due to a lack of proper screening and early diagnosis. This study aims to find out the prevalence of cervical cancer among cervical biopsies in a tertiary care center.

A descriptive cross-sectional study was conducted among the hospital records of cervical biopsies from the department of pathology of Shree Birendra Hospital from 1st May 2018 to 30th April 2019. Ethical approval was taken from the Institutional Review Committee in February 2020. This study was conducted among 146 cervical biopsies by using convenience sampling method. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Data were analyzed using excel 2016 software.

The prevalence of cervical cancer among 146 cases included in our study is found to be 6 (4.11%) at 95% Confidence Interval (0.90-7.32). Among those cases of cervical cancer, 4 (66.67%) were squamous cell carcinoma, 1 (16.67%) was adenocarcinoma, and 1 (16.67%) was of other type. Maximum cases of cervical cancer were prevalent among higher age groups.

Cervical cancer-related morbidity and mortality are different in different parts of the world. It's burden is primarily seen in developing countries where there is a lack of effective screening programs.

Cervical cancer-related morbidity and mortality are different in different parts of the world. It's burden is primarily seen in developing countries where there is a lack of effective screening programs.

The management of glaucoma following cataract surgery (GFCS) in children is challenging. This study looks at the results of two-site trabeculotomy in paediatric aphakic/pseudophakic glaucoma, 1-year post operatively.

This prospective, institutional study was performed on 33 eyes with GFCS in patients aged ≤14 years. Patients underwent two-site trabeculotomy using the rigid-probe trabeculotome, through a superonasal and an inferotemporal scleral flap. Tetrazolium Red concentration Intraocular pressure (IOP), medications, complications and success rates at 1 year were reported. Success was defined as IOP < 23 mmHg or 30% IOP reduction, on the same or fewer number of medications at 1 year, without the need for another glaucoma procedure.

Trabeculotomy was performed on average 3.5 years after the cataract surgery. Patients were aged 5.73 ± 1.79 years. We excluded four eyes in which >180° incision could not be achieved. A 360° incision was achieved in 14 eyes (48%). There was a significant reduction in IOP and medications at 1, 3, 6 and 12 months (p < 0.

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