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BACKGROUND Peer support is recognized globally as an essential recovery service for people with mental health conditions. With the influx of digital mental health services changing the way mental health care is delivered, peer supporters are increasingly using technology to deliver peer support. In light of these technological advances, there is a need to review and synthesize the emergent evidence for peer-supported digital health interventions for adults with mental health conditions. OBJECTIVE The aim of this study was to identify and review the evidence of digital peer support interventions for people with a lived experience of a serious mental illness. METHODS This systematic review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) procedures. The PubMed, Embase, Web of Science, Cochrane Central, CINAHL, and PsycINFO databases were searched for peer-reviewed articles published between 1946 and December 2018 that examined digital peer support interventions forogies. CONCLUSIONS Digital peer support interventions appear to be feasible and acceptable, with strong potential for clinical effectiveness. However, the field is in the early stages of development and requires well-powered efficacy and clinical effectiveness trials. TRIAL REGISTRATION PROSPERO CRD42020139037; https//www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID= 139037. ©Karen L Fortuna, John A Naslund, Jessica M LaCroix, Cynthia L Bianco, Jessica M Brooks, Yaara Zisman-Ilani, Anjana Muralidharan, Patricia Deegan. Originally published in JMIR Mental Health (http//mental.jmir.org), 03.04.2020.Because of high rates of 2019 novel coronavirus disease in Wuhan, China, Wuhan Blood Center began screening for severe acute respiratory syndrome coronavirus 2 RNA on January 25, 2020. We screened donations in real-time and retrospectively and found plasma samples positive for viral RNA from 4 asymptomatic donors.This article describes an indirect composite restoration technique for diastema closure and tooth lengthening with a noninvasive approach using regularly available materials such as silicone, composite resin, and an adhesive system. The procedure resulted in occlusal and functional improvement, with diastema closure, protrusive guide adjustment, and an increase in central incisor length. The procedure provided an adequate proportion of the central incisors with an esthetically natural appearance. It also resulted in simple, fast, and accurate manufacturing with a noninvasive esthetic indirect rehabilitation compared with more invasive preparation of ceramic veneers.OBJECTIVE To evaluate the effect of deep margin elevation on structural and marginal integrity of ceramic inlays. METHODS AND MATERIALS Forty extracted human third molars were collected and randomly separated into four groups (n=10/group). In group 1 (enamel margin group), the gingival margin was placed 1 mm supragingival to the cemento-enamel junction (CEJ). In group 2 (cementum margin group), the gingival margin was placed 2 mm below the CEJ. https://www.selleckchem.com/products/RO4929097.html In group 3 (glass ionomer [GI] margin group), the gingival margin was placed 2 mm below the CEJ, and then the margin elevated with GI to the CEJ. In group 4 (resin-modified glass ionomer [RMGI] margin group), the gingival margin was placed 2 mm below the CEJ, and then the margin elevated with RMGI to the CEJ. Standardized ceramic class II inlays were fabricated with computer-aided design/computer-aided manufacturing and bonded to all teeth, and ceramic proximal box heights were measured. All teeth were subjected to 10,000 cycles of thermocycling (5°C/55°C) and then underwent 1,200,000 cycles of vertical chewing simulation at 50 N of force. Ceramic restorations and marginal integrity were assessed with a Hirox digital microscope. The Fisher exact test (two-tailed) with adjusted p-values (α=0.05) and logistic regression were used for statistical analysis. RESULTS The cementum margin group had a significantly higher ceramic fracture rate (90%) compared to other groups (10% in enamel margin and GI margin groups, p=0.007; 0% in RMGI group, p less then 0.001). Logistic regression showed that with increased ceramic proximal box heights, the probability of ceramic fracture increased dramatically. CONCLUSION Deep marginal elevation resulted in decreased ceramic fracture when preparation margins were located below the CEJ. There was no difference found between margin elevation with GI or RMGI. Increased heights of ceramic proximal box may lead to an increased probability of ceramic fracture.OBJECTIVES To evaluate the effect of tack cure on polymerization shrinkage (PS) of resin-based luting cements. METHODS AND MATERIALS One composite resin cement, Duo-Link (Duolink); two self-adhesive resin cements, RelyX U200 (U200) and G-CEM LinkAce (GCem); and one resin-modified glass ionomer cement, RelyX Luting Plus (Luting+), were used for measuring PS in light-cure (LC group), self-cure (SC group), and two tack-cure modes that were light cured (TC-LC group) or self-cured (TC-SC group) after tack cure. PS was measured by a modified bonded disc method for 1600 seconds and analyzed with two-way analysis of variance and Tukey honestly significant difference test. To investigate the effect of tack cure on light cure or self-cure, data were analyzed with an independent-samples t-test with tack cure as a variable. The significance level was 5%. RESULTS Regarding cure mode, Duolink showed a significantly lower PS in the TC-SC group compared with the other groups. Luting+ showed a significantly lower PS in the TC-SC group than in the SC group. U200 showed a significantly lower PS in the self-cure groups compared with that in the light-cure groups. The PS of GCem was not affected by cure mode. Regarding cements, Luting+ showed the highest PS, followed by GCem, Duolink, and U200 (p less then 0.05). Self-cure of Duolink and Luting+ was negatively affected by tack cure, while light cure was not affected. U200 and GCem were not affected by tack cure either in the self-cure or light-cure groups. CONCLUSION For the tested cements, tack cure decreased the PS of Duolink and Luting+ when they were self-cured after tack cure. When the cements were light cured after tack cure, PS was not affected by tack cure in any cement.

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