Myersparker9852

6 min, group 2 = 34 ± 14.8 min, P = 0.4) was not statistical significant between groups. The incidence of post-operative complications were similar in both groups (P = 0.95). Conclusion Manual small incision cataract surgery with trabeculectomy is noninferior in PXG patients with comparable surgical outcomes, when compared with phacoemulsification with trabeculectomy.Purpose To study and document electron microscopic features in explanted hydrophobic microvacuoles affected acrylic intraocular lenses (IOL) which were in vivo for an average duration of 11 years. Methods Scanning electron microscopic (SEM; Hitachi S 3000 N EXAX Genesis VP SEM) study of five explanted hydrophobic acrylic IOL which had clinically evident microvacuoles prior to explantation, was done. The IOLs were in vivo for a prolonged period and needed explantation for various indications. Only those hydrophobic acrylic IOLs which fulfilled the inclusion criteria were included. The findings were compared with control specimens. Results The IOLs were in vivo for an average duration of 11.6 ± 4.21 years. The cause of explantation of IOL was subluxation in four cases and low visual acuity in one case. Bulk degradation and microvacuoles on cut sections throughout the IOL optics and undulating surface patterns over both the surfaces of the IOL has been documented in all the specimens. No such findings were noted in the control specimens where the surface and texture were homogenous. Conclusion SEM findings of the structural changes in explanted IOL documented in the study demonstrate that hydrophobic acrylic IOL is degradable in vivo. Microvacuoles are a clinical manifestation of the structural changes that occur at a microscopic and molecular level. These changes are not seen in IOLs which have not undergone intraocular implantation. To our knowledge, a similar study of this kind has not been done.Purpose To evaluate the clinical outcome following intraoperative transzonular intravitreal injection of triamcinolone acetonide and moxifloxacin in patients undergoing phacoemulsification cataract extraction with intraocular lens (IOL) implantation. Methods In this prospective, non-randomized, clinical, interventional study, a total of 200 eyes were enrolled. Patients who voluntarily gave their consent after being informed about dropless cataract surgery along with its pros and cons were included. Those who had glaucoma or were known steroid responders as well as those who were lost to follow-up were excluded. 0.1 ml each of moxifloxacin (500 mg) and triamcinolone acetonide (4 mg) were injected transzonularly following IOL implantation in phacoemulsification cataract surgery with the help of 27G curved cannula. Slit-lamp examination was done to detect cells, visual acuity was noted, and intraocular pressure was measured postoperatively on day 1, 7, 30, 60, and 90. Results Uncorrected visual acuity (UCVA) greater than 6/9 was achieved in 96% of patients at the end of 3 months. The mean IOP was found to be normal in all the cases at every visit. Twenty patients complained of floaters on postoperative day 1 (D1), which decreased to zero after 60 days (D60). None of the patients needed any eye drop during the entire postoperative period. Conclusion The study demonstrates that this procedure is advantageous and safe.Purpose To analyze the reliability of the refractive results prediction obtained in intraocular lens (IOL) calculation using bicylindric power calculation method, with the use of steep and flat keratometry readings compared with the classical mean keratometry calculation method. selleck kinase inhibitor Methods Fifty-seven eyes of 57 subjects who underwent cataract surgery were included in this prospective study. Optical biometry was performed with IOLMaster 700 and IOL power calculation was performed using both keratometry readings and the surgically induced astigmatism. Four weeks after surgery, subjective refraction was done. Finally, results obtained with both IOL calculation methods were compared. Results Mean spherical equivalent using bicylindric IOL power calculation method was -0.082 ± 0.296D, and achieved mean spherical equivalent using classical IOL power method with Haigis formula was -0.088 ± 0.405D. Achieved mean spherical equivalent obtained in subjective refraction after surgery was -0.101 ± 0.265D. Linear correlation between bicylindric method spherical equivalent calculation and achieved spherical equivalent was statistically significant (r = 0.761, P less then 0.001), also correlation between Haigis spherical equivalent calculation and achieved spherical equivalent was statistically significant (r = 0.339, P = 0.010). Emmetropia was achieved in 49 of 57 (85.86%) subjects and bicylindric method calculated that 49 of 57 (85.86%) of subjects would get emmetropia (P = 1.000). Classical IOL power calculation estimated that 38/57 subjects would get emmetropia (66.67%) (P = 0.026). Conclusion The IOL power calculation including both keratometry readings and surgically induced astigmatism seems to be more accurate and provides more precision in refractive prediction than classical calculation method.Purpose Zernike polynomials for describing ocular higher order aberrations are affected by pupil aperture. The current study aimed to validate Mahajan's formula for scaling Zernike polynomials by pupil size. Methods Higher order aberrations for 3 intraocular lens models (AcrySof IQ IOL SN60WF, Technis ZA9003, Adapt Advanced Optics) were measured using the Zywave aberrometer and a purpose-built physical model eye. Zernike coefficients were mathematically scaled from a 5 mm to a 3 mm pupil diameter (53 mm), from a 5 mm to a 2 mm pupil diameter (52 mm), and from a 3 mm to a 2 mm pupil diameter (32 mm). Agreement between the scaled coefficients and the measured coefficients at the same pupil aperture was assessed using the Bland-Altman method in R statistical software. Results No statistically significant mean difference (MD) occurred between the scaled and measured Zernike coefficients for 21 of 23 analyses after Holm-Bonferroni correction (P > 0.05). Mean differences between the scaled and measured Zernike coefficients were clinically insignificant for all aberrations up to the fourth order, and within 0.