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Qualitative and quantitative data highlight the positive effect that LRLD can have on pediatric patients as they transition from childhood to adolescence to young adulthood.

As pediatric transplant centers in the United States soon mark 30years of performing live-liver donation, recipients are becoming adults and understanding more clearly that the long-term effects of such donations will lead to improvements in future care.

As pediatric transplant centers in the United States soon mark 30 years of performing live-liver donation, recipients are becoming adults and understanding more clearly that the long-term effects of such donations will lead to improvements in future care.

Improvements in chronic disease management has led to increasing numbers of youth transitioning to adult healthcare. Poor transition can lead to high risks of morbidity and mortality. Understanding adolescents and young adults (AYA) perspectives on transition is essential to developing effective transition preparation. The aim of this metasynthesis was to synthesize qualitative studies assessing the experiences and expectations of transition to adult healthcare settings in AYAs with chronic diseases to update work completed in a prior metasynthesis by Fegran, Hall, Uhrenfeldt, Aagaard, and Ludvigsen (2014).

A search of PubMed, Medline, PsycINFO, and CINAHL was conducted to gather articles published after February 2011 through June 2019.

Of 889 articles screened, a total of 33 articles were included in the final analysis.

Seven main themes were found developing transition readiness, conceiving expectations based upon pediatric healthcare, transitioning leads to an evolving parent role, transitioning leads to an evolving youth role, identifying barriers, lacking transition readiness, and recommendations for improvements.

Findings of this metasynthesis reaffirmed previous findings. AYAs continue to report deficiencies in meeting the Got Transition® Six Core Elements. The findings highlighted the need to create AYA-centered transition preparation which incorporate support for parents.

Improvements in transition preparation interventions need to address deficiencies in meeting the Got Transition® Six Core Elements. More research is needed to identify and address barriers implementing the transition process.

Improvements in transition preparation interventions need to address deficiencies in meeting the Got Transition® Six Core Elements. More research is needed to identify and address barriers implementing the transition process.Analysis of longitudinal within-person networks over the course of therapy allows an identification of possible targets of treatment. This study examined within-person networks of clinical features in social anxiety disorder (SAD) patients during cognitive (CT) and interpersonal (IPT) therapy. Patients (n = 80) were randomized to either CT or IPT in a 10 week residential program. They completed a measure of clinical features two times a week. The 60 (75 %) patients who had completed at least 18 measurements were included in the analyses. The multilevel vector autoregressive (mlVAR) model was used to analyze the data, producing a temporal, contemporaneous, and between-person network. In the temporal network and as expected, more homework compliance in a half-week predicted less social anxiety and less social avoidance the subsequent half-week. Also better social function predicted less social avoidance, whereas more social anxiety predicted more self-focus. Unexpectedly, less social avoidance predicted more self-focus and less self-focus predicted less social function and social joy. In the contemporaneous network, self-focus, anxiety and avoidance displayed a conditional independence structure. The estimated temporal network suggests that homework compliance and social function are promising targets of treatment.

The influence of squatting during delivery on maternal and fetal outcomes remains unclear. Edralbrutinib BTK inhibitor We performed a systematic review and meta-analysis to evaluate the benefits and risks of adopting a squatting position during the second stage of labor.

Search Strategy A systematic search in the three major electronic databases (CENTRAL, PubMed and Embase) was performed, from their respective inception dates to the 14th of December 2019, using 'squatting', and a combination of keywords to identify delivery. Eligibility criteria Randomized controlled trials comparing squatting position to any supine position during the second stage of labor.

Risk ratio for dichotomous outcomes, mean difference for continuous outcomes, with 95 % confidence intervals. Fixed-effects meta-analysis (Mantel-Haenszel method) or random-effects model (inverse variance method), for low and high heterogeneity between trials, respectively. PROSPERO Registration number CRD42018093244 RESULTS Seven randomized controlled trials (n = 1219) were it squatting, women should be able to choose the position they prefer.

To evaluate adverse neonatal and maternal outcomes among women with obesity and no additional comorbidities at 37-41 weeks.

This was a population based retrospective cohort study performed using US vital statistics data from 2014-2017. We included women with body mass index ≥ 30.0 kg/m

and a singleton, cephalic, non-anomalous pregnancy who attempted labor and delivered between 37 0/7-41 6/7 weeks. Women with chronic hypertension, gestational diabetes, or pregestational diabetes were excluded. The co-primary outcomes were composite neonatal morbidity (Apgar score < 5 at 5 min, assisted ventilation > 6 h, neonatal seizures, or neonatal death within 27 days) and composite maternal morbidity (admission to the intensive care unit, blood transfusion, uterine rupture, or unplanned hysterectomy) with completed weeks of gestation as the primary exposure variable. All outcomes were examined using multivariate Poisson regression and were reported as adjusted risk ratios (aRR) with 95 % confidence intervals (95 % CI).

There were 15.8 million live births between 2014-2017, of whom 5.1 million (32.1 %) met the inclusion criteria. Composite neonatal morbidity was significantly increased in women delivering at 37 weeks (aRR 1.84; 95 % CI 1.78-1.90), 38 weeks (aRR 1.14; 95 % CI 1.10-1.17), 40 weeks (aRR 1.19; 95 % CI 1.16-1.22), and 41 weeks (aRR 1.49; 95 % CI 1.44-1.53) compared to 39 weeks. Composite maternal morbidity was similarly increased at 37 weeks (aRR 1.26; 95 % CI 1.19-1.34), 38 weeks (aRR 1.07; 95 % CI 1.02-1.13), 40 weeks (aRR 1.16; 95 % CI 1.11-1.20), and 41 weeks (aRR 1.42; 95 % CI 1.34-1.49).

Composite neonatal and maternal morbidity among women with obesity and no additional comorbidities is increased with delivery at 37, 38, 40, or 41 weeks compared with 39 weeks.

Composite neonatal and maternal morbidity among women with obesity and no additional comorbidities is increased with delivery at 37, 38, 40, or 41 weeks compared with 39 weeks.

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