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In the propensity-score matched cohort, the postoperative 30-day mortality rate was 0.75% (n = 85) in the regional anesthesia group (Odds Ratio, 0.567; 95% CI, 0.434 to 0.741; P = 0.00003) compared with 1.31% (n = 149) in the general anesthesia group. Regional anesthesia was also associated with a reduced rate of ICU admission compared with that of patients who received general anesthesia (0.44% vs. 2.68%; OR, 0.161; 95% CI, 0.119 to 0.217, P  less then  0.00001). There was a nonsignificant relationship between the anesthetic technique and postoperative blood transfusion (P = 0.082). CONCLUSIONS The results of this observational, propensity score-matched cohort study suggest a significant association between regional anesthesia and low thirty-day mortality and a worse postoperative prognosis in patients who underwent noncardiac- and nonneurosurgery, which provides information for anesthetic technique decision making in the clinical setting. PURPOSE With increasing healthcare costs and the emergence of new technologies in vascular surgery, economic evaluations play a critical role in informing decision-making that optimizes patient outcomes while minimizing per-capita costs. The objective of this systematic review was to describe all English published economic evaluations in vascular surgery and to identify any significant gaps in the literature. METHODS We conducted a comprehensive English literature review of EMBASE, MEDLINE, The Cochrane Library, Ovid Health Star, and Business Source Complete from inception until December 1, 2018. Two independent reviewers screened articles for eligibility using pre-determined inclusion criteria and subsequently extracted data. Articles were included if they compared two or more vascular surgery interventions using either a partial economic evaluation (cost analysis) or full economic evaluation (cost-utility, cost-benefit, and/or cost-effectiveness analysis). Data extracted included publishing journal, date ofal in pursuing interventions that simultaneously optimize cost and patient outcomes. The literature is lacking in full economic evaluations - a trend persistent in other surgical specialties - and there is a need for full economic evaluations to be conducted in the field of vascular surgery. Crown All rights reserved.INTRODUCTION We report a rare case of delayed, symptomatic thoracic endograft thrombosis after the initial TEVAR for blunt thoracic aortic injury (BTAI) which was successfully retreated with a redo TEVAR, followed by open conversion due to recurrent partial occlusion of the distal edge of the endografts. METHODS Two years ago, a 22-year-old man had undergone an emergency TEVAR for BTAI. A Zenith Cook 22 x 100 mm (Cook Incorporated, Bloomington, IN) endograft was used. Six months later he underwent an emergency endovascular relining of the endograft using the same type of device. The multi-organ perfusion was completely restored except for the spinal cord injury. After eight months a recurrent partial occlusion of the distal edge of the second graft was documented. The thoracic aorta was replaced with a 22-mm silver coated graft (Maquet Spain, S.L.U.). TPCA-1 in vitro Histology exam showed a neointimal formation, thickening and fibrosis of the inner 1/3 of the media with loss of smooth muscle cells and increase of the elastic fibers. CONCLUSION The need of secondary interventions or open conversion due to potential complications after TEVAR for traumatic aortic injury is an additional consideration when weighing the risks and benefits of endovascular repair and subsequent surveillance strategies. AIMS To explore the effects of statin therapy with the abdominal aortic aneurysm (AAA) growth rate and mortality. METHODS Databases of PubMed, Embase, Ovid, Wanfang and China National Knowledge Infrastructure (CNKI) database were investigated for eligible literatures from their establishments to May, 2019. Included studies were selected according to precise eligibility criteria. Statistical analysis were performed by RevMan 5.3 software. RESULTS Fourteen studies with a total of 38749 patients of whom 15993 underwent statins treatment and 22756 underwent placebo or conventional therapy were eligible for meta-analysis. The pooled results indicated that the statin use was related to a significantly lower AAA growth rate (Mean Difference=-1.5 mm/y; 95% CI=-1.99 to -1.02; p less then 0.00001). In addition, statins can significantly reduce the short-term mortality (in-hospital or 30-day) (Odds Ratio =0.63; 95% CI=0.56-0.7; p less then 0.00001) and long-term mortality (1 year after surgery) after AAA repair (Odds Ratio =0.67; 95% CI=0.61-0.74; p less then 0.00001). CONCLUSIONS This meta-analysis revealed statin therapy can reduce the risks of AAA growth rates and mortality. However, due to its significant heterogeneity in the included studies, the consequence should be understand with caution. INTRODUCTION The impact of a coordinated, multispecialty limb salvage program combined with aggressive multi-tibial revascularization upon limb salvage rates, survival, and cost of care has not previously been elucidated. The purpose of this paper is to present a clinical management algorithm developed over a four-year period that can significantly improve amputation-free survival in critical limb ischemia (CLI) patients. METHODS This study is a prospective, single center analysis to evaluate the clinical, quality of care, and financial outcomes in CLI patients who undergo aggressive revascularization and wound care. Patient demographics, comorbidities, and procedure details measured with outcomes tabulated at the index procedure and at successive three-month intervals out to one year. RESULTS A total of 186 patients who underwent endovascular interventions for Rutherford 4+ CLI were followed for a one-year period between 2016 and 2019. The average ABI improved from 0.49 +/- 0.21 prior to treatment to 0.74 +/- 0.23 at one year (P less then 0.001). The immediate technical success rate was 95.7%, defined as the number of patients with inline flow from the aorta to the foot. 33.4% of patients required a minor amputation and 7.3% of patients required a major amputation by one year. Crude all-cause mortality at one year was 17.7%. The total direct cost of care was $31,797 at one year, but significantly lower for the atherectomy with DES group ($24,442, P less then 0.001). 5.7% of patients eventually required open surgical bypass. CONCLUSIONS Inline revascularization paired with a coordinated limb salvage program can significantly improve outcomes in CLI patients. Appropriate endovascular management of CLI patients can lead to durable results with a high amputation-free survival.