Selfherskind8790

Global climate change has the potential to disrupt agricultural systems, undermine household socioeconomic status, and shape the prevalence and distribution of diseases. Each of these changes may influence children's nutritional status, which is sensitive to food availability, access, and utilization, and which may have lasting consequences for later-life health and socioeconomic outcomes. This paper contributes to the emerging literature on climate and child health by studying the effects of temperature and precipitation exposures on children's height and weight in Indonesia. Drawing on five rounds of the Indonesian Family Life Survey (IFLS) implemented between 1993 and 2015, we estimate fixed-effects regression models of height-for-age (HFA) and weight-for-height (WFH) among samples of children ages 24-59 months and 0-23 months, respectively. We test for heterogeneity in these effects across sub-populations expected to vary in their vulnerability. Results show that delays in monsoon onset are consistently associated with worse child health outcomes. Delays in monsoon onset during the prenatal period are associated with reduced child height among children age 2-4 years. The weight of young ( less then 2 years) children is adversely affected by delays in the most recent monsoon season, and this relationship is particularly strong among residents of Java. Overall, our results underline the need for interventions that protect children's nutrition and underlying health against the effects of climate change.Fatal drug overdose represents a significant public health threat in Philadelphia, but substantial variation exists across its communities. This study uses negative binomial longitudinal regression to model ZIP code overdose fatalities over a seven-year period. Model covariates indicate that structural inequality, police arrest activity, and features of the built environment are associated with increased mortality across ZIP codes. Additionally, fatalities are spatially concentrated in select geographies of the city. These findings emphasize the pertinence of community ecological features in the production of stratified within-city health outcomes, and inform the geographic distribution of harm reduction interventions.This study reviews the evidence on the effects of nature in the study environment on well-being, academic outcomes, and outcomes related to possible explanatory pathways among students in secondary and tertiary education. The protocol was preregistered at Prospero (CRD42019126718). A systematic search of two databases yielded 3410 articles, of which 37 studies were included in the review. Most studies had a high risk of bias and there were heterogeneous outcome and exposure measures. Hence, no firm conclusions could be drawn. However, potentially promising leads were found on the associations between campus green space and improved quality of life, perceived restoration, lower outdoor temperature, and between indoor nature and improved indoor climate.During the first years of a baby's life, parents develop ways of caring that affect the child's health later in life. In this paper, we focus on eating and sleeping, as social practices that mediate between socioeconomic and cultural conditions and health outcomes, such as weight status. We argue for an analysis of what we call 'family health competence', meaning emerging know-hows and resources relevant to healthy living produced, embodied and shared by household members, to understand the development of health practices of first-time parents and their children. In an ethnographic panel study in the Netherlands, we follow households pre-birth until the first child turns age four. Our analysis suggests that across different families, competences develop enabling parents to balance a) attaching and b) detaching in particular ways. Parents learn how to observe and interpret their new-borns, bracket doubt, build trust, manage time pressures and mobilize support networks. These competences are partly class and gender-specific while there is also significant diversity within class and gender. The competence to balance attachment and detachment can be understood as the effect of contradictory social norms and institutional (labour market and care) provisions typical for late-modern welfare states.Iron plays a key role in secondary neuronal injury after intracerebral hemorrhage (ICH), and hepcidin is able to reduce brain iron in iron-overloaded rats by down-regulating iron transport proteins including ferroportin 1 and transferrin receptor 1. These led us to hypothesize that hepcidin might reduce iron-mediated neurotoxicity by inhibiting iron accumulation in ICH brain. Here, we examined effects of Ad-hepcidin (hepcidin expression adenovirus) on the nonheme iron contents, expression of hepcidin, ferritin and iron transport proteins, neuronal cell survival, water contents in the brain and/or cerebrospinal fluid (CSF), and ICH-induced apoptosis, neurological deficit by RT-PCR, Western blot analysis, NeuN Immunofluorescence, TUNEL, Fluoro-Jade B staining, behavioral performance and Morris water-maze tests in 510 rats. We demonstrated that hepcidin could significantly suppress the ICH-induced increase in iron and ferritin in brain tissues and CSF by inhibiting expression of iron transport proteins, increase neuronal survival by attenuating ICH-induced apoptosis, reactive oxygen species, neurodegeneration and brain edema, as well as effectively improve ICH-induced behavioral and cognitive deficit in rats. The findings collectively showed that hepcidin could effectively attenuate iron-mediated secondary neuronal injury after ICH in rats. This naturally existing protein can potentially be developed into a therapeutic drug for the treatment of ICH patients.

The present study evaluated the incidence of postembolization syndrome (PES) after endovascular coil embolization of the gonadal veins (EEGV) in patients with pelvic congestion syndrome and investigated the appropriate medical treatment.

EEGV was performed in 70 female patients with pelvic congestion syndrome (left-sided in 58, right-sided in 3, and bilateral in 9 patients). For embolization, 0.035-in. coils with an 8- to 12-mm diameter and 10- to 20-cm length were used. Assessments of the EEGV results and possible PES symptoms were performed on days 1, 5, 10, 20, and 30 after the procedure and included transvaginal and transabdominal duplex ultrasound scanning of the pelvic veins and at the embolization site.

PES had manifested with increased pelvic pain, tenderness along the embolized vein, and hyperthermia ≤37.5°C to 37.8°C and had developed in 14 patients (20%). CDK inhibitor For PES treatment, a nonsteroidal anti-inflammatory drug (diclofenac, 75mg daily for 3-7days; mean, 4.2± 1.1days) and a venoactive drug (micronized purified flavonoid fraction, 1000mg daily for 2months) were used.