Wolfeodom6990

05, the ISLSOF did not differ significantly at any particular age group but only overall mean of all the three age groups (n=15) presented the difference significantly. The MICW showed significant difference (p less then 0.05) at two age groups; young and the middle-age. The LICL and ITLW values are highly significant (p less then 0.01) and the HBC value was also significant (p less then 0.05) all at the middle age. No significant difference was recorded between the two sexes in the aged Kuri cattle; indicating that the female tends to progressively increase in size beyond 5 years old thereby making these values insignificant from the male counterpart at old age. In conclusion, the middle-age Kuri cattle have the most sexually dimorphic osteometric landmarks in the skull with the male having higher values than the female. This data will be useful for anatomical, developmental, anthropological forensic and clinical studies, and form basis for comparison with other breeds of cattle.The excessive consumption of high cholesterol diet has been associated with an increased incidence of obesity. This is because obesity induced pathologies with high mortality, such as complications of dyslipidaemia, diabetes mellitus, arthritis, hypertension, myocardial infarction, and hepatocellular carcinoma. Although the associated, disease are enhanced by formation of oxidative stress, lipid peroxidation and hypercholesterolaemia. Magnesium chloride is found to be beneficial in a wide range of diseases. Magnesium is one of the most neglected mineral in human body. It is crucial for a healthy and lasting life. Magnesium is responsible for the activation of more than 300 enzymes in the body. The present study intends to determine the protective effect of magnesium chloride on liver enzyme and biomarker of oxidative stress in high fat diet fed rats. Twenty (20) adult Male Wistar rats weighing (100 - 150) grams randomly divided into three treatments and one control groups of five rats each (n = 5). Group I NoT and GPx level of the high fat diet fed groups, co-administered with   250 and 500 MgCl2, when compared with the high fat diet fed group only. Also, the lipid peroxidation shows significant (p less then 0.05) decrease in the groups administered the two doses of Magnesium chloride (250 and 500 mg/kg) respectively as compared to control. In relation to the liver enzyme, the showed that there were significant (p less then 0.05) changes in value of AST, ALT and ALP in the group co-administered with the two doses of the Magnesium chloride compared to the control. The result showed that high-fat diet induces ROS, dyslipidaemia and release of biological metabolite, as evidenced by the rise in oxidative stress and activities of liver enzymes. MgCl2 administration also protected the body against rise in the metabolites despite consumption of high-fat diet by the Wistar Rats.Epidural anesthesia is routinely used in ruminants for obstetric manipulations and caudal surgical procedures owing to complications associated with general anaesthesia in this species. Castration is a common farm practice for derived production benefits. The responses of a castrate to anaesthesia may differ from that of an intact animal because of possible anaesthetic-hormonal interplay. This study compared the anaesthetic indices, haemato- biochemical parameters (PCV, Hb, WBC, PLT, Na+, K+, Cl-, urea, creatinine, Cu2+) between castrated and intact goats subjected to epidural anaesthesia with tramadol-lidocaine mixture. Experimental animals were six West African Dwarf (WAD) goats (3 intact and 3 castrated bucks). The drugs were administered into the lumbosacral epidural space. Heart rate, respiratory rate and rectal temperature at 15minutes interval for 90minutes and anaesthetic indices were taken. Blood was obtained for haematology and serum chemistry before drug administration and hourly thereafter for threated measures. There was reduction in pre-treatment values of some of the haematological, biochemical and hormonal values especially urea in the non- castrate (pre-treatment value-of 22±4.16 and 3-hour post treatment value of 13.3±0.33). The combination of tramadol-lignocaine epidurally is safe in castrate animals as well as in intact animals especially West African dwarf goats as there were no deleterious effects. However, further studies could combine adrenaline for prolonged recumbency when required.Infertility is generally regarded as a major clinical problem, and it adversely affects people both psychologically and medically. In this study, the changes in gonadal oxidative stress markers and reproductive function of BALB/c mice were investigated. Forty-eight (48) BALB/c mice acquired for this study were randomly divided into four (4) groups of eight (8) mice each. Each group was further sub-divided into male and female groups with equal number of mice. The groups were represented as thus Group A normal mice; Group B mice infected with Plasmodium berghei; Group C Plasmodium berghei infected mice treated with Artemether/Lumefantrine; Group D Plasmodium berghei infected mice treated with Vitamin E. The experimental mice were inoculated with the Plasmodium berghei, and the parasites were confirmed in the mice four days later before the commencement of the experiments. After the experimental procedures which lasted for fourteen (14) days, the mice were sacrificed, blood samples collected for serum testostertrine and Vitamin E also decreased the oxidative stress level of the gonads and improved the histological features of the testes and ovaries of the infected mice. This study therefore showed Plasmodium berghei infection posed anti-fertility threat while treatment with Artemether/Lumefantrine and Vitamin E ameliorates the effect of the parasites.The World Health Organization (WHO) estimates that, about a quarter of the diseases facing mankind today occur due to prolonged exposure to environmental pollution, and that most of these environment-related diseases are however, not easily detected and may be acquired during childhood and manifested later in adulthood. The aim of this work was to evaluate sub-chronic effects of lead poisoning on haematological parameters and some sex hormones, as well as age-related changes on Wistar Rats. GSK2636771 purchase Thirty (30) of 3-, 5-, and 7-months old male Wistar rats, were divided into experimental (lead fed) and control (distil water) groups. Haematological parameters were determined, while blood lead concentration was determined using the method of Atomic Absorption Spectrophotometer. There was a significant (P less then 0.05) increase (46.00, 46.75, 50.75 vs 14.56, 18.00, 17.60) in blood lead concentration with insignificant (P˃ 0.05) increase in the concentration of WBC counts (12.433, 13.000, 12.250 Vs 12.400, 10.000, 11.250) between the experimental and control groups.