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Obesity, as an epidemic disease, is distributed among all age groups, including children, adolescents, adults, and the elderly. The goal of this study was to investigate the knowledge, attitude, and practice (KAP) concerning obesity among university students.

In total, 1,317 questionnaires were filled out by 1,317 (466 male and 851 female) randomly selected students aged range from 16 to 24. All participants agreed to provide personal information in this study. A self-designed questionnaire was applied to collect demographic characteristics and assess the KAP of obesity. Gender, height, weight, grade, sleep and income were included in the population questionnaire. Descriptive statistics was used to analyze the respondent rate of KAP among students.

In the survey, 64.9% of respondents believed that obesity was a disease. Only a few people cared about their body shape. Most of the participants in the study had practices that were detrimental to their health, including irregular dieting (52.9%), surfing the internet, and playing games (58.5%) in their spare time.

This study identified that lacking knowledge of obesity was common among college students. Most respondents had a positive attitude about preventing obesity by focusing on dieting and exercise. Thus, education related to obesity should be strengthening among university students to translate attitude into practice.

This study identified that lacking knowledge of obesity was common among college students. Most respondents had a positive attitude about preventing obesity by focusing on dieting and exercise. Thus, education related to obesity should be strengthening among university students to translate attitude into practice.

Non-valvular atrial fibrillation (NVAF) is a common type of AF, and patients with NVAF have a higher risk of ischemic stroke than non-AF patients. This study aims to investigate the goal attainment of international normalized ratio (INR) in patients with NVAF after anticoagulation therapy, and to analyze the risk factors that affect the goal attainment of INR.

NVAF patients who were admitted to our hospital from December 2019 to December 2020 and received anticoagulation therapy were selected as the research subjects. The INR goal attainment of patients was assessed, the risk factors affecting INR goal attainment were analyzed, and a ROC curve was drawn to evaluate the predictive value of risk factors for INR goal attainment in NVAF patients.

After anticoagulation treatment, the INR of 42 cases reached the target (INR value ≥0.2, the goal attainment group), and the INR of 74 cases did not reach the target (INR value <2.0, the non-goal attainment group). The age, mean platelet volume (MPV), platelet d the goal attainment of INR after anticoagulant therapy in NVAF patients. For patients with risk factors, clinicians can formulate a reasonable individualized anticoagulant drug regimen based on the above-mentioned index levels.

Cardiovascular diseases have become a prominent threat to public health and quality of life. In recent years, some studies have reported that ivabradine can improve the cardiac function and prognosis of patients with acute myocardial infarction (AMI).

We searched China National Knowledge Infrastructure (CNKI), Wanfang database, Chinese Biomedical Literature (CBM), Chongqing Weipu Chinese Sci-tech Journal Database (VIP), PubMed, Cochrane Library, and EMBASE for randomized controlled trials (RCTs) of ivabradine in the treatment of AMI from January 1980 until December 2020. Each RCT was systematically reviewed.

A total of 7 RCTs with 658 patients were included. Compared with the control group, the heart rate [mean deviation (MD) =-9.20, 95% confidence interval (CI) -13.03 to -5.38, P<0.00001] and brain natriuretic peptide (BNP) (MD =-112.73, 95% CI -186.12 to -39.35, P=0.003) of patients who received ivabradine combined with conventional standard treatment were significantly lower and left ventricular ejection fraction (LVEF) (MD =3.17, 95% CI 2.12 to 4.23, P<0.00001) was significantly better. The difference in adverse events was not statistically significant [odds ratio (OR) =2.45, 95% CI 0.92 to 6.55, P=0.07].

Ivabradine combined with β-blockers can reduce the resting heart rate and improve heart function in patients with AMI while not increasing adverse events. However, due to limitations in the number and quality of studies included, our conclusions need to be further confirmed by analyzing more studies.

Ivabradine combined with β-blockers can reduce the resting heart rate and improve heart function in patients with AMI while not increasing adverse events. However, due to limitations in the number and quality of studies included, our conclusions need to be further confirmed by analyzing more studies.

Allergic rhinitis is a chronic inflammatory disease with a high incidence, affecting the quality of life of patients. The aim of the present study was to explore the expression and clinical significance of vascular endothelial cell adhesion molecule-1 (VCAM-1), interleukin (IL)-6, and IL-17A in patients with allergic rhinitis.

A total of 180 patients with allergic rhinitis, who were admitted to our hospital from March 2017 to March 2020, were enrolled as the observation group. Patients were further divided into 3 subgroups according to the degree of severity of allergic rhinitis as follows the mild group (n=66), the moderate group (n=60), and the severe group (n=54). During the same period, 188 people without allergic rhinitis, who underwent physical examination in our hospital, were enrolled as the control group. VCAM-1, IL-6, and IL-17A levels were compared between these groups, and the correlation between the 3 levels and allergic rhinitis was analyzed.

VCAM-1, IL-6, and IL-17A levels in the observatroles in allergic rhinitis, and the concentration will increase with disease progression. Clinical testing of VCAM-1, IL-6, IL-17A should be increased to improve the diagnostic rate for early allergic rhinitis and to prevent disease progression.

To explore the effect of the in situ simulation teaching method in the emergency training of trainee nurses.

A total of 108 trainee nurses from the First Affiliated Hospital of Hainan Medical College were selected, and in situ simulation teaching was employed in emergency training. Following the in situ simulation teaching training, a questionnaire was issued to evaluate CIPP (context evaluation, input evaluation, process evaluation, product evaluation) simulation teaching, clinical thinking ability, nursing team cooperation, and student satisfaction. These data were then collected and statistical analysis was conducted.

The response rate of this teaching questionnaire was 100%. After using in situ simulation teaching to instruct trainee nurses in emergencies, the satisfaction rate of the trainee nurses was 94.9%, and the satisfaction rate of the instructor with the trainee nurses was 92.2%. AEBSF mouse After in-situ simulation teaching, the clinical thinking ability (critical thinking ability, systematic thinking ability, evidence-based thinking ability), teamwork ability (trust, team orientation, support, shared mental model and team leadership), the theoretical and clinical practice ability had been improved.

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