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A number of epidemics, including the SARS-CoV-1 epidemic of 2002-2004, have been known to exhibit superspreading, in which a small fraction of infected individuals is responsible for the majority of new infections. The existence of superspreading implies a fat-tailed distribution of infectiousness (new secondary infections caused per day) among different individuals. Here, we present a simple method to estimate the variation in infectiousness by examining the variation in early-time growth rates of new cases among different subpopulations. We use this method to estimate the mean and variance in the infectiousness, β, for SARS-CoV-2 transmission during the early stages of the pandemic within the United States. We find that σβ/μβ ≳ 3.2, where μβ is the mean infectiousness and σβ its standard deviation, which implies pervasive superspreading. This result allows us to estimate that in the early stages of the pandemic in the USA, over 81% of new cases were a result of the top 10% of most infectious individuals.Understanding segregation plays a significant role in determining the development pathways of a country as it can help governmental and other concerned agencies to prepare better-targeted policies for the needed groups. However, inferring segregation through alternative data, apart from governmental surveys remains limited due to the non-availability of representative datasets. In this work, we utilize Call Data Records (CDR) provided by one of Estonia's major telecom operators to research the complexities of social interaction and human behavior in order to explain gender segregation. We analyze the CDR with two objectives. First, we study gender segregation by exploring the social network interactions of the CDR. We find that the males are tightly linked which allows information to spread faster among males compared to females. Second, we perform the micro-analysis using various users' characteristics such as age, language, and location. Our findings show that the prime working-age population (i.e., (24,54] years) is more segregated than others. We also find that the Estonian-speaking population (both males and females) are more likely to interact with other Estonian-speaking individuals of the same gender. Further to ensure the quality of this dataset, we compare the CDR data features with publicly available Estonian census datasets. We observe that the CDR dataset is indeed a good representative of the Estonian population, which indicates that the findings of this study reasonably reflect the reality of gender segregation in the Estonian Landscape.We executed two live animal ranking experiments, own-flock and group-animal ranking, to identify the breeding objectives of Arab and Oromo goat keepers in northwestern Ethiopia as a preliminary step towards designing sustainable breeding programs for two goat populations. In the own-flock ranking experiment, a total of 147 households, out of which 46 were Arab and 101 were Oromo goat keepers that live in semi-arid and sub-humid agroecologies respectively, were visited at their homesteads and were asked to choose their first best, second best, third best and the most inferior does from their own flock. The reasons of ranking and life history of the does (age, previous production and reproduction information) were inquired and recorded; live body weight and some linear body measurements were taken. In the group-animal ranking experiment, 12 breeding does and 12 breeding bucks from Arab goats and the same number of animals from Oromo goats were randomly selected. Life history of selected does and bucks (age, bircolor, body size and body conformation. Simultaneous use of both own-flock and group-animal ranking experiments is advisable to identify breeding objective traits in production systems where record keeping is absent.

Many men living with HIV want to have children. Opportunities to reduce periconception HIV transmission include antiretroviral therapy as prevention, pre-exposure prophylaxis, limiting condomless sex to peak fertility, and sperm processing. Whether men have knowledge of or want to adopt these strategies remains unknown.

We conducted focus group discussions (FGDs) with men accessing HIV care in South Africa in 2014 to inform a safer conception intervention for men. Eligible men were 25-45 years old, living with HIV, not yet accessing treatment, and wanting to have a child with an HIV-negative or unknown serostatus female partner (referred to as the "desired pregnancy partner"). FGDs explored motivations for having a healthy baby, feasibility of a clinic-based safer conception intervention, and acceptability of safer conception strategies. Data were analyzed using thematic analysis.

Twelve participants from three FGDs had a median age of 37 (range 23-45) years, reported a median of 2 (range 1-4) sexual pa partners.

Men living with HIV expressed interest in safer conception and willingness to attend clinic programs. Selleck CQ211 Imprecise prevention counseling messages make it difficult for men to conceptualize risk reduction. Effective safer conception programs should embrace clear language, e.g. undetectable = untransmittable (U = U), and support multiple approaches to serostatus disclosure to pregnancy partners.

Related evidences of metabolically unhealthy profile of adults with normal weight are not well characterized in the Chinese population. This is because they cannot be effectively identified by regular measurements (such as body mass index [BMI]). To overcome this gap in literature, this study aimed at investigating the association between body composition and metabolically unhealthy profile in Chinese adults with normal weight.

A total of 5427 individuals with normal-weight were recruited from 15820 people living in Ningxia Hui Autonomous Region in Northwest China. Normal-weight was defined as a BMI of 18.5-23.9 kg/m2. Metabolically unhealthy profile was assessed by the National Cholesterol Education Program Adult Treatment Panel III (ATP III). Metabolically unhealthy normal-weight (MUHNW) profile was defined in individuals who had normal weight and at least two cardiometabolic risk factors. Generalized linear model was used to investigate the association between body composition measured by bioelectrical impedance and metabolically unhealthy profile in adults with normal-weight.

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